Now showing items 532-551 of 1301

    • Gadolinium Chloride Rescues Niemann-Pick Type C Liver Damage 

      Cortez, Cristián [Univ Mayor, Fac Sci, Ctr Genom & Bioinformat, Santiago 8580745, Chile]; Klein, Andrés D.; Esteban Oyarzún, Juan; Zanlungo, Silvana (MDPI, 2018)
      Niemann-Pick type C (NPC) disease is a rare neurovisceral cholesterol storage disorder that arises from loss of function mutations in the NPC1 or NPC2 genes. Soon after birth, some patients present with an aggressive ...
    • Galactic or extragalactic chemical tagging for NGC3201? Discovery of an anomalous CN-CH relation 

      Araya, I. [Univ Mayor, Fac Ciencias, Nucleo Matemat Fis & Estadist, Santiago, Chile]; Dias, B.; Nogueira-Cavalcante, J. P.; Saker, L.; Shokry, A. (EDP SCIENCES S A, 2018)
      Context. The origin of the globular cluster (GC) NGC 3201 is under debate. Its retrograde orbit points to an extragalactic origin, but no further chemical evidence supports this idea. Light-element chemical abundances are ...
    • Gelatinolytic activity in gingival crevicular fluid from teeth with periapical lesions 

      Pabst, Carolina [Chile. Universidad Mayor]; Martínez, Benjamín [Chile. Universidad Mayor]; Hernández, Marcela [Universidad de Chile] (CIENCIAS, 2008)
      Objective. Many matrix metalloproteinases ( MMPs) have been associated with periodontal tissue destruction during chronic and apical periodontitis. The aim of this study was to determine gelatinolytic activity in gingival ...
    • Gender differences in legal outcomes of filicide in Austria and Finland 

      Fernández Arias, P. [Univ Mayor, Soc & Hlth Res Ctr, Santiago, Chile]; Amon, S.; Putkonen, H.; Weizmann-Henelius, G.; Klier, C. M. (SPRINGER WIEN, 2019)
      Female offenders of filicide have been found to receive more lenient legal handling than male offenders. We aimed to discover these possible gender differences in the legal outcome of filicide cases. This was a binational ...
    • Gene expression and chromosomal location for susceptibility to Sjogren's syndrome 

      Anaya, Juan-Manuel [Colombia.Universidad del Rosario]; Aguilera, Sergio [Chile. Universidad Andrés Bello]; Úrzua, Ulises [Universidad de Chile]; Munroe, David [Estados Unidos. National Institutes of Health NIH]; Molina, Claudio [Chile. Universidad Mayor] (CIENCIAS, 2009)
      Primary Sjögren's syndrome (SS) is a chronic inflammatory autoimmune disease affecting mainly the exocrine glands. Its physio-pathology is poorly understood and most of the knowledge has been related to the inflammatory ...
    • Gene Families, Epistasis and the Amino Acid Preferences of Protein Homologs 

      Ferrada, Evandro [Univ Mayor, Fac Sci, Ctr Genom & Bioinformat] (SAGE PUBLICATIONS LTD, 2019)
      In order to preserve structure and function, proteins tend to preferentially conserve amino acids at particular sites along the sequence. Because mutations can affect structure and function, the question arises whether the ...
    • Generation of a protocol for the synthesis of chitosan nanoparticles loaded with florfenicol through the ionic gelation method 

      Parodi, Jorge [Univ Mayor, Fac Ciencias Vicerrectoria Invest & Postgrad, Lab Biol Celular & Mol Aplicada, Temuco, Chile]; Carmona, Erico R.; Plaza, Tania; Recio-Sánchez, Gonzalo (UNIV NACIONAL MAYOR SAN MARCOS, 2018)
      The formation of nanoparticles of chitosan by the ionic gelation method has a high potential for loading, transport and controlled release of molecules. It is a simple method and the nanoparticles have good absorption, ...
    • Genome sequence of Vibrio VPAP30, isolated from an episode of massive mortality of reared larvae of scallop Argopecten purpuratus 

      Rojas R., Miranda C.D., Asenjo F.; Romero, Jaime [Centro de Genómica y Bioinformatica, Facultad de Ciencias, Universidad Mayor, Chile]; Valderrama, Katherinne [Microbial Pathogenesis & Vaccinol Res Grp, ‎Facultad de Ciencias, Universidad Mayor, Chile]; Segovia, Cristopher [Microbial Pathogenesis & Vaccinol Res Grp, ‎Facultad de Ciencias, Universidad Mayor, Chile]; Ugalde, Juan A. [Centro de Genómica y Bioinformatica, Facultad de Ciencias, Universidad Mayor, Chile]; Santander, Javier [Microbial Pathogenesis & Vaccinol Res Grp, ‎Facultad de Ciencias, Universidad Mayor, Chile] (American Society for Microbiology, 2015)
      We report here the 5.167-Mbp draft genome sequence of Vibrio VPAP30, isolated from an Argopecten purpuratus larval culture. Vibrio VPAP30 is the etiological agent of a vibriosis outbreak causing a complete collapse of a ...
    • Genome sequencing and analysis of the first complete genome of Lactobacillus kunkeei strain MP2, an Apis mellifera gut isolate 

      Olmos, Alejandro [Chile. Universidad Mayor. Centro de Genómica y Bioinformática]; Henríquez-Piskulich, Patricia [Chile. Universidad Mayor]; Polanco, Víctor [Chile. Universidad Mayor. Centro de Genómica y Bioinformática]; Aldea, Patricia [Chile. Universidad Mayor]; Trombert, Annette N. [Chile. Universidad Mayor. Centro de Genómica y Bioinformática] (CIENCIAS, 2016)
      BACKGROUND: The honey bee (Apis mellifera) is the most important pollinator in agriculture worldwide. However, the number of honey bees has fallen significantly since 2006, becoming a huge ecological problem nowadays. The ...
    • Genome-wide circulating microRNA expression profiling reveals potential biomarkers for amyotrophic lateral sclerosis 

      Manuel Matamala, José [Univ Mayor, Ctr Genom & Bioinformat, Fac Sci, Santiago, Chile]; Arias-Carrasco, Raúl [Univ Mayor, Ctr Genom & Bioinformat, Fac Sci, Santiago, Chile]; Sánchez, Carolina [Univ Mayor, Ctr Genom & Bioinformat, Fac Sci, Santiago, Chile]; Uhrig, Markus [Univ Mayor, Ctr Genom & Bioinformat, Fac Sci, Santiago, Chile]; Maracaja-Coutinho, Vinicius [Univ Mayor, Ctr Genom & Bioinformat, Fac Sci, Santiago, Chile]; Manque, Patricio [Univ Mayor, Ctr Genom & Bioinformat, Fac Sci, Santiago, Chile]; Bargsted, Leslie; Matus, Soledad; Abarzúa, Sebastián; van Zundert, Brigitte; Verdugo, Renato (ELSEVIER SCIENCE INC, 2018)
      The occurrence of mutations of TDP-43, FUS, and C9ORF72 in amyotrophic lateral sclerosis (ALS) suggests pathogenic alterations to RNA metabolism and specifically to microRNA (miRNA) biology. Moreover, several ALS-related ...
    • Genomic positional conservation identifies topological anchor point RNAs linked to developmental loci 

      Arias-Carrasco, Raúl [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Santiago, Chile]; Maracaja-Coutinho, Vinicius [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Santiago, Chile]; Amaral, Paulo P.; Leonardi, Tommaso; Han, Namshik; Vire, Emmanuelle; Gascoigne, Dennis K.; Buscher, Magdalena; Pandolfini, Luca; Zhang, Anda; Pluchino, Stefano; Nakaya, Helder, I; Hemberg, Martin; Shiekhattar, Ramin; Enright, Anton J.; Kouzarides, Tony (BMC, 2018)
      Background: The mammalian genome is transcribed into large numbers of long noncoding RNAs (lncRNAs), but the definition of functional lncRNA groups has proven difficult, partly due to their low sequence conservation and ...
    • Genotyping and Persistence of Candida albicans from Pregnant Women with Vulvovaginal Candidiasis 

      Tapia C.V., Hermosilla G., Fortes P., Bucarey S., Salinas H., Rodas P.I., Díaz M.C., Magne F.; Alburquenque, Claudio [Escuela de Tecnología Médica, Universidad Mayor, Chile] (Springer Netherlands, 2017)
      Objective To study Candida albicans genotypes using RAPD and their susceptibility to fluconazole in healthy pregnant women and in vulvovaginal candidiasis (VVC) patients after topical treatment with clotrimazole. Methods ...
    • Geoglam best available crop-specific global maps: Strengths and limitations 

      Barker B., Becker-Reshef I.; Oliva, Patricia [Hemera Centro de Observación de la Tierra, Facultad de Ciencias, Universidad Mayor, Chile] (IEEE, 2018)
      An accurate global map of current cropland is needed to tackle the agricultural challenges of the next decades. Several remote sensing products have provided with global cropland maps. To create the GEOGLAM best available ...
    • Giant mandibular bone defect: Report of a case 

      Sindermann, D. B [Chile. Universidad Mayor]; Rondanelli, B. M. [Chile. Universidad Mayor] (CIENCIAS, 2006)
      In 1942 Edward Stafne1 described a series of 35 cases of asymptomatic radiolucent bone cavities next to the mandibular angle. The cavities seemed to be spheric.PERIHUEICO or elliptic monolocular radiolucencies, well defined, ...
    • Ginecomastia y pseudoginecomastia: Tratamiento 

      Cabello P, Rodrigo [Pontificia Universidad Católica de Chile]; Israel, Guillermo, V. [Pontificia Universidad Católica de Chile]; Calderón M, Daniel [Chile. Universidad Mayor] (CIENCIAS, 2009)
      La Ginecomastia, mamas femeninas, es la anomalía más frecuente en el sexo masculino. La pseudoginecomastia es un cuadro que a menudo se confunde con la ginecomastia y consiste en el aumento de tejido graso en la región ...
    • Gingival metastasis from a testicular choriocarcinoma: An unusual case report and review of the literature. 

      Aguilar, Leonardo [Universidad de Chile]; Pastrian, Juan [Universidad de Chile]; Mebus, Cristina [Universidad de Chile]; Martínez, Benjamín [Chile. Universidad Mayor] (CIENCIAS, 2013)
      Los tumores metastásicos a la cavidad bucal son lesiones extremadamente raras que representan el 1% de todas las neoplasias malignas bucales y maxilofaciales. La mayoría de los casos reportados afectan más a los huesos ...
    • Global ecological predictors of the soil priming effect 

      Abades, Sebastián [Univ Mayor, GEMA Ctr Genom Ecol & Environm]; Bowker, Matthew A. [Univ Mayor, GEMA Ctr Genom Ecol & Environm]; Bastida, Felipe; Bastidal, Felipe; Garcia, Carlos; Fierer, Noah; Eldridge, David J.; Alfaro, Fernando D.; Berhe, Asmeret Asefaw; Cutler, Nick A.; Gallardo, Antonio; Garcia-Velazquez, Laura; Hart, Stephen C.; Hayese, Patrick E.; Hernández, Teresa; Hseu, Zeng-Yei; Jehmlich, Nico; Kirchmair, Martin; Lambers, Hans; Neuhauser, Sigrid; Pena-Ramírez, Víctor M.; Pérez, Cecilia A.; Reed, Sasha C.; Santos, Fernanda; Siebe, Christina; Sullivan, Benjamin W.; Trivedi, Pankaj; Vera, Alfonso; Williams, Mark A.; Moreno, JoséLuis; Delgado-Baquerizo, Manuel (NATURE PUBLISHING GROUP, 2019)
      Identifying the global drivers of soil priming is essential to understanding C cycling in terrestrial ecosystems. We conducted a survey of soils across 86 globally-distributed locations, spanning a wide range of climates, ...
    • Global phylogeography and ancient evolution of the widespread human gut virus crAssphage 

      Trefault, Nicole [Univ Mayor, GEMA Ctr Genom Ecol & Environm, Huechuraba, Chile]; Edwards, Robert A.; Vega, Alejandro A.; Norman, Holly M.; Ohaeri, Maria; Levi, Kyle; Dinsdale, Elizabeth A.; Cinek, Ondrej; Aziz, Ramy K.; McNair, Katelyn; Barr, Jeremy J.; Bibby, Kyle; Brouns, Stan J. J.; Cazares, Adrian; de Jonge, Patrick A.; Desnues, Christelle; Díaz Muñoz, Samuel L.; Fineran, Peter C.; Kurilshikov, Alexander; Lavigne, Rob; Mazankova, Karla; McCarthy, David T.; Nobrega, Franklin L.; Reyes Muñoz, Alejandro; Tapia, German; Trefault, Nicole; Tyakht, Alexander, V; Vinuesa, Pablo; Wagemans, Jeroen; Zhernakova, Alexandra; Aarestrup, Frank M.; Ahmadov, Gunduz; Alassaf, Abeer; Anton, Josefa; Asangba, Abigail; Billings, Emma K.; Cantu, Vito Adrian; Carlton, Jane M.; Cazares, Daniel; Cho, Gyu-Sung; Condeff, Tess; Cortés, Pilar; Cranfield, Mike; Cuevas, Daniel A.; De la Iglesia, Rodrigo; Decewicz, Przemyslaw; Doane, Michael P.; Dominy, Nathaniel J.; Dziewit, Lukasz; Elwasila, Bashir Mukhtar; Murat Eren, A.; Franz, Charles; Fu, Jingyuan; Garcia-Aljaro, Cristina; Ghedin, Elodie; Gulino, Kristen M.; Haggerty, John M.; Head, Steven R.; Hendriksen, Rene S.; Hill, Colin; Hyoty, Heikki; Ilina, Elena N.; Irwin, Mitchell T.; Jeffries, Thomas C.; Jofre, Juan; Junge, Randall E.; Kelley, Scott T.; Mirzaei, Mohammadali Khan; Kowalewski, Martin; Kumaresan, Deepak; Leigh, Steven R.; Lipson, David; Lisitsyna, Eugenia S.; Llagostera, Montserrat; Maritz, Julia M.; Marr, Linsey C.; McCann, Angela; Molshanski-Mor, Shahar; Monteiro, Silvia; Moreira-Grez, Benjamin; Morris, Megan; Mugisha, Lawrence; Muniesa, Maite; Neve, Horst; Nam-phuong Nguyen; Nigro, Olivia D.; Nilsson, Anders S.; O'Connell, Taylor; Odeh, Rasha; Oliver, Andrew; Piuri, Mariana; Prussin, Aaron J., II; Qimron, Udi; Quan, Zhe-Xue; Rainetova, Petra; Ramírez-Rojas, Adan; Raya, Raul; Reasor, Kim; Rice, Gillian A. O.; Rossi, Alessandro; Santos, Ricardo; Shimashita, John; Stachler, Elyse N.; Stene, Lars C.; Strain, Ronan; Stumpf, Rebecca; Torres, Pedro J.; Twaddle, Alan; Ibekwe, MaryAnn Ugochi; Villagra, Nicolás; Wandro, Stephen; White, Bryan; Whiteley, Andy; Whiteson, Katrine L.; Wijmenga, Cisca; Zambrano, María M.; Zschach, Henrike; Dutilh, Bas E. (NATURE PUBLISHING GROUP, 2019)
      Microbiomes are vast communities of microorganisms and viruses that populate all natural ecosystems. Viruses have been considered to be the most variable component of microbiomes, as supported by virome surveys and examples ...
    • Gluconeogenic Enzymes in beta-Cells: Pharmacological Targets for Improving Insulin Secretion 

      Gatica, Rodrigo [Univ Mayor, Fac Ciencias, Escuela Vet]; Westermeier, Francisco; Holyoak, Todd; Asenjo, Joel L.; Nualart, Francisco; Burbulis, Ian; Bertinat, Romina (ELSEVIER SCIENCE LONDON, 2019)
      Pancreatic beta-cells express the gluconeogenic enzymes glucose 6-phosphatase (G6Pase), fructose 1,6-bisphosphatase (FBP), and phosphoenolpyruvate (PEP) carboxykinase (PCK), which modulate glucose-stimulated insulin secretion ...
    • Gradient sperm selection for reproductive techniques in cattle: Is Isolate a suitable replacement for Percoll? 

      Sepúlveda, B. [Univ Mayor, Fac Med, Sch Obstet & Childcare, Temuco, Chile]; Arias, M. E.; Aguila, L.; Zambrano, F.; Sánchez, R.; Felmer, R. (WILEY, 2018)
      In assisted reproductive techniques, it is essential to perform a sperm selection to obtain spermatozoa with high motility and membrane integrity for in vitro fertilisation (IVF) and high-DNA integrity for intracytoplasmic ...