• Gadolinium Chloride Rescues Niemann-Pick Type C Liver Damage 

      Cortez, Cristián [Univ Mayor, Fac Sci, Ctr Genom & Bioinformat, Santiago 8580745, Chile]; Klein, Andrés D.; Esteban Oyarzún, Juan; Zanlungo, Silvana (MDPI, 2018)
      Niemann-Pick type C (NPC) disease is a rare neurovisceral cholesterol storage disorder that arises from loss of function mutations in the NPC1 or NPC2 genes. Soon after birth, some patients present with an aggressive ...
    • Galactic or extragalactic chemical tagging for NGC3201? Discovery of an anomalous CN-CH relation 

      Araya, I. [Univ Mayor, Fac Ciencias, Nucleo Matemat Fis & Estadist, Santiago, Chile]; Dias, B.; Nogueira-Cavalcante, J. P.; Saker, L.; Shokry, A. (EDP SCIENCES S A, 2018)
      Context. The origin of the globular cluster (GC) NGC 3201 is under debate. Its retrograde orbit points to an extragalactic origin, but no further chemical evidence supports this idea. Light-element chemical abundances are ...
    • Gaps, biases, and future directions in research on the impacts of anthropogenic land-use change on aquatic ecosystems: a topic-based bibliometric analysis 

      Fernández, Francisco J. [Univ Mayor, Sch Agron, Fac Sci, Chile]; Muñoz, Manuel; Ponce Oliva, Roberto D.; Vásquez-Lavín, Felipe; Gelcich, Stefan (SPRINGER HEIDELBERG, 2021-08)
      Anthropogenic land use change (ALUC) satisfies human needs but also impacts aquatic ecosystems. Aquatic ecosystems are intrinsically linked with terrestrial landscapes, an association that is already recognized as a key ...
    • Garantía de imparcialidad en la Comisión para el Mercado Financiero, a propósito del procedimiento administrativo sancionador consagrado en la Ley N° 21.000 

      Villablanca Cerda, Lusitania [Chile. Universidad Mayor. Escuela de Derecho] (Universidad de Talca, 2020-08)
      En este texto se analiza la Ley Nº 21.000, que creó la Comisión para el Mercado Financiero respecto uno de sus dos principales objetivos: modernizar el procedimiento sancionatorio. Más precisamente, este examen concierne ...
    • Gelatinolytic activity in gingival crevicular fluid from teeth with periapical lesions 

      Pabst, Carolina [Chile. Universidad Mayor]; Martínez, Benjamín [Chile. Universidad Mayor]; Hernández, Marcela [Universidad de Chile] (CIENCIAS, 2008)
      Objective. Many matrix metalloproteinases ( MMPs) have been associated with periodontal tissue destruction during chronic and apical periodontitis. The aim of this study was to determine gelatinolytic activity in gingival ...
    • Gender Differences between Multimorbidity and All-Cause Mortality among Older Adults 

      Roman Lay, Alejandra Andrea; Ferreira do Nascimento, Carla; Caba Burgos, Fresia; Larraín Huerta, Angélica Del Carmen; Rivera Zeballos, René Eduardo; Pantoja Silva, Verónica [Núcleo Ciencias Biológicas, Facultad de Estudios Interdisciplinarios, Universidad Mayor, Chile]; Oliveira Duarte, Yeda Aparecida de (Hindawi Publishing Corporation, 2020-02)
      Objectives: This study seeks to determine the prevalence of chronic diseases and analyze the association between multimorbidity and all-cause mortality by sex. Methods: This is a 16-year longitudinal study of follow-up. ...
    • Gender differences in legal outcomes of filicide in Austria and Finland 

      Fernández Arias, P. [Univ Mayor, Soc & Hlth Res Ctr, Santiago, Chile]; Amon, S.; Putkonen, H.; Weizmann-Henelius, G.; Klier, C. M. (SPRINGER WIEN, 2019)
      Female offenders of filicide have been found to receive more lenient legal handling than male offenders. We aimed to discover these possible gender differences in the legal outcome of filicide cases. This was a binational ...
    • Gene expression and chromosomal location for susceptibility to Sjogren's syndrome 

      Anaya, Juan-Manuel [Colombia.Universidad del Rosario]; Aguilera, Sergio [Chile. Universidad Andrés Bello]; Úrzua, Ulises [Universidad de Chile]; Munroe, David [Estados Unidos. National Institutes of Health NIH]; Molina, Claudio [Chile. Universidad Mayor] (CIENCIAS, 2009)
      Primary Sjögren's syndrome (SS) is a chronic inflammatory autoimmune disease affecting mainly the exocrine glands. Its physio-pathology is poorly understood and most of the knowledge has been related to the inflammatory ...
    • Gene Families, Epistasis and the Amino Acid Preferences of Protein Homologs 

      Ferrada, Evandro [Univ Mayor, Fac Sci, Ctr Genom & Bioinformat] (SAGE PUBLICATIONS LTD, 2019)
      In order to preserve structure and function, proteins tend to preferentially conserve amino acids at particular sites along the sequence. Because mutations can affect structure and function, the question arises whether the ...
    • Gene Regulatory Networks of Penicillium echinulatum 2HH and Penicillium oxalicum 114-2 Inferred by a Computational Biology Approach 

      Lenz, Alexandre Rafael; Galán-Vásquez, Edgardo; Balbinot, Eduardo; de Abreu, Fernanda Pessi; Souza de Oliveira, Nikael; da Rosa, Leticia Osorio; de Avila e Silva, Scheila; Camassola, Marli; Dillon, Aldo Jose Pinheiro; Pérez-Rueda, Ernesto [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Chile] (Frontiers Media S.A., 2020-10)
      Penicillium echinulatum 2HH and Penicillium oxalicum 114-2 are well-known cellulase fungal producers. However, few studies addressing global mechanisms for gene regulation of these two important organisms are available so ...
    • Generation of a protocol for the synthesis of chitosan nanoparticles loaded with florfenicol through the ionic gelation method 

      Parodi, Jorge [Univ Mayor, Fac Ciencias Vicerrectoria Invest & Postgrad, Lab Biol Celular & Mol Aplicada, Temuco, Chile]; Carmona, Erico R.; Plaza, Tania; Recio-Sánchez, Gonzalo (UNIV NACIONAL MAYOR SAN MARCOS, 2018)
      The formation of nanoparticles of chitosan by the ionic gelation method has a high potential for loading, transport and controlled release of molecules. It is a simple method and the nanoparticles have good absorption, ...
    • Generative Models Of Morphogenesis In Developmental Biology 

      Stillman, Namid R.; Mayor, Roberto [Univ Mayor, Fac Sci, Ctr Integrat Biol, Santiago, Chile] (2023)
    • Genetic Analysis As A Tool To Improve The Monitoring Of Stranded Cetaceans In Chile 

      Kraft, Sebastian; Rodríguez, Francisca; Olavarría, Carlos; Poulin, Elie; Perez-Alvarez, Maria José [Univ Mayor, Escuela Med Vet, Fac Med & Ciencias Salud, Chile] (2023)
    • GENETIC CHARACTERIZATION OF HONEY BEES (Apis mellifera) IN THE DRY COASTAL ZONE OF THE O'HIGGINS REGION, CHILE 

      Barriga, Nicolas F.; Durán, Naomi M. [Univ Mayor, Ctr Estudios Apicola CEAPIMAYOR, Fac Ciencias, Chile]; Aldea, Patricia L. [Univ Mayor, Ctr Estudios Apicola CEAPIMAYOR, Fac Ciencias, Chile] (Universidad de Concepción. Facultad de Agronomía, Facultad de Ingeniería Agrícola y Facultad de Ciencias Veterinarias, 2021-01)
      The natural diversity of the honey bee (Apis mellifera) includes five evolutionary lineages and 26 subspecies, currently described that come from Africa, Europe, and the Middle East. They were introduced by humans to almost ...
    • Genome sequence of Vibrio VPAP30, isolated from an episode of massive mortality of reared larvae of scallop Argopecten purpuratus 

      Rojas R., Miranda C.D., Asenjo F.; Romero, Jaime [Centro de Genómica y Bioinformatica, Facultad de Ciencias, Universidad Mayor, Chile]; Valderrama, Katherinne [Microbial Pathogenesis & Vaccinol Res Grp, ‎Facultad de Ciencias, Universidad Mayor, Chile]; Segovia, Cristopher [Microbial Pathogenesis & Vaccinol Res Grp, ‎Facultad de Ciencias, Universidad Mayor, Chile]; Ugalde, Juan A. [Centro de Genómica y Bioinformatica, Facultad de Ciencias, Universidad Mayor, Chile]; Santander, Javier [Microbial Pathogenesis & Vaccinol Res Grp, ‎Facultad de Ciencias, Universidad Mayor, Chile] (American Society for Microbiology, 2015)
      We report here the 5.167-Mbp draft genome sequence of Vibrio VPAP30, isolated from an Argopecten purpuratus larval culture. Vibrio VPAP30 is the etiological agent of a vibriosis outbreak causing a complete collapse of a ...
    • Genome sequencing and analysis of the first complete genome of Lactobacillus kunkeei strain MP2, an Apis mellifera gut isolate 

      Olmos, Alejandro [Chile. Universidad Mayor. Centro de Genómica y Bioinformática]; Henríquez-Piskulich, Patricia [Chile. Universidad Mayor]; Polanco, Víctor [Chile. Universidad Mayor. Centro de Genómica y Bioinformática]; Aldea, Patricia [Chile. Universidad Mayor]; Trombert, Annette N. [Chile. Universidad Mayor. Centro de Genómica y Bioinformática] (CIENCIAS, 2016)
      BACKGROUND: The honey bee (Apis mellifera) is the most important pollinator in agriculture worldwide. However, the number of honey bees has fallen significantly since 2006, becoming a huge ecological problem nowadays. The ...
    • Genome sequencing reveals molecular subgroups in oral epithelial dysplasia 

      Márquez, Agustín; Mujica, Isidora; Jordán, Natalia; Báez, Pablo; Tarquinio, Sandra; Nunes, Jean; Adorno, Daniela; Martínez, Benjamín [Univ Mayor, Fac Dent, Santiago, Chile]; Morales-Pisón, Sebastián [Univ Mayor, Precis Oncol Ctr, Santiago, Chile]; Fernández-Remires, Ricardo [Univ Mayor, Fac Med & Heatlh Sci, Santiago, Chile] (SOCIEDADE BRASILEIRA DE PESQUISA ODONTOLOGICA, 2023-07-16)
      This study aimed to analyze the molecular characteristics of oral epithelial dysplasia (OED), highlighting the pathways and variants of genes that are frequently mutated in oral squamous cell carcinoma (OSCC) and other ...
    • Genome-based classification of Acidihalobacter prosperus F5 (=DSM 105917=JCM 32255) as Acidihalobacter yilgarnensis sp. nov 

      Khaleque, Himel Nahreen; González, Carolina [Chile. Universidad Mayor. Facultad de Ciencias. Centro de Investigación de Genómica y Bioinformática]; Johnson, D Barrie; Kaksonen, Anna H.; Holmes, David S. [Chile. Universidad Mayor. Facultad de Ciencias. Centro de Investigación de Genómica y Bioinformática]; Watkin, Elizabeth L. J. (MICROBIOLOGY SOCIETY, 2020-12)
      The genus Acidihalobacter has three validated species, Acidihalobacter ferrooxydans, Acidihalobacter prosperus and Acidihalobacter aeolinanus, all of which were isolated from Vulcano island, Italy. They are obligately ...


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