Now showing items 21-40 of 1301

    • A Simulation Study Using Terrestrial LiDAR Point Cloud Data to Quantify Spectral Variability of a Broad-Leaved Forest Canopy 

      Cifuentes, Renato [Univ Mayor, Fac Ciencias, Hemera Ctr Observac Tierra, Santiago 8340589, Chile]; Van der Zande, Dimitry (MDPI, 2018)
      In this analysis, a method for construction of forest canopy three-dimensional (3D) models from terrestrial LiDAR was used for assessing the influence of structural changes on reflectance for an even-aged forest in Belgium. ...
    • A standardized objective structured clinical examination to assess clinical competencies in medical students 

      Hurtado, Amelia [Univ Mayor, Santiago, Chile]; Giaconi, Elisa [Univ Mayor, Santiago, Chile]; Behrens, Claudia; Morales, Veronica; Parra, Paula; Fernández, Rosario (SOC MEDICA SANTIAGO, 2018)
      Background: Outcomes-based education is a trend in medical education and its assessment is one of the main challenges. The Objective Structured Clinical Examination (OSCE) is one of the tools used to assess clinical ...
    • A Tomato Tocopherol-Binding Protein Sheds Light on Intracellular alpha-Tocopherol Metabolism in Plants 

      del Pozo, Talia [Univ Mayor, Fac Ciencias, Ctr Conservac & Propagac Vegetal CEPROVEG, Santiago, Chile]; Bermudez, Luisa; Lira, Bruno Silvestre; de Godoy, Fabiana; Boos, Irene; Romano, Cecilia; Previtali, Viola; Almeida, Juliana; Brehelin, Claire; Asis, Ramon; Quadrana, Leandro; Demarco, Diego; Alseekh, Saleh; Salinas Gamboa, Rigel; Pérez-Flores, Laura; Guadalupe Dominguez, Pia; Rothan, Christophe; Fernie, Alisdair Robert; González, Mauricio; Stocker, Achim; Hemmerle, Andreas; Clausen, Mads Hartving; Carrari, Fernando; Rossi, Magdalena (OXFORD UNIV PRESS, 2018)
      Tocopherols are non-polar compounds synthesized in the plastids, which function as major antioxidants of the plant cells and are essential in the human diet. Both the intermediates and final products of the tocopherol ...
    • A typology of prescription drug monitoring programs: a latent transition analysis of the evolution of programs from 1999 to 2016 

      Castillo-Carniglia, Alvaro [Univ Mayor, Fac Humanidades, Soc & Hlth Res Ctr, Santiago, Chile]; Smith, Nathan; Martins, Silvia S.; Kim, June; Rivera-Aguirre, Ariadne; Fink, David S.; Henry, Stephen G.; Mooney, Stephen J.; Marshall, Brandon D. L.; Davis, Corey; Cerda, Magdalena (WILEY, 2019)
      Background and aims Prescription drug monitoring programs (PDMP), defined as state-level databases used in the United States that collect prescribing information when controlled substances are dispensed, have varied ...
    • Aberrant localization of ezrin correlates with salivary acini disorganization in Sjogren's Syndrome 

      Aguilera, Sergio [Chile. Universidad Mayor]; Olea, Nancy [Estados Unidos. NIH National Institute of Dental & Craniofacial Research]; González, Maria-Julieta [Universidad de Chile] (CIENCIAS, 2010)
      OBJECTIVES: To analyse whether the alterations in the structure and organization of microvilli in salivary acinar cells from SS patients are linked to changes in the expression and/or cellular localization of ezrin. METHODS: ...
    • Aberrant localization of fusion receptors involved in regulated exocytosis in salivary glands of Sjogren's syndrome patients is linked to ectopic mucin secretion. 

      Barrera, María José [Universidad de Chile]; Sánchez, Marianela [Universidad de Chile]; Aguilera, Sergio [Chile. Clínica INDISA]; Alliende, Cecilia [Universidad de Chile]; Bahamondes, Verónica [Universidad de Chile]; Molina, Claudio [Chile. Universidad Mayor]; Leyton, Cecilia [Universidad de Chile]; Quest, Andrew F.G. [Universidad de Chile]; Urzúa, Ulises [Universidad de Chile]; Castro, Isabel [Universidad de Chile]; González, Sergio [Chile. Universidad Mayor]; Sung, Hsiao Hsin [Universidad de Chile]; Albornoz, Amelina [Universidad de Chile]; Hermoso, Marcela [Universidad de Chile]; González, María-Julieta [Universidad de Chile] (Facultad de Ciencias, 2012)
      Sjögren's syndrome (SS) is a chronic inflammatory autoimmune disease that mainly affects tear and salivary glands, whereby SS-patients frequently complain of eye and mouth dryness. Salivary acinar cells of SS-patients ...
    • ABL1 kinase inhibitors for the treatment of Niemann-Pick disease type A 

      Cortez, Cristián [Univ Mayor, Santiago, Chile]; Zanlungo, Silvana; Marin, Tamara; De la Fuente, Catalina; Acuna, Mariana; Campos, Fabian; Castro, Juan; Leal, Nancy; Marugan, Juan; Dulcey, Andres; Gorshkov, Kirill; Zheng, Wei; Carmo-Fonseca, Maria; Alvarez, Alejandra R. (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2020)
      Sin resumen
    • Ablation of brainstem C1 neurons improves cardiac function in volume overload heart failure 

      Andrade, David C. [Univ Mayor, Ctr Invest Fisiol Ejercicio, Santiago, Chile]; Toledo, Camilo; Díaz, Hugo S.; Lucero, Claudia; Arce-Alvarez, Alexis; Oliveira, Luiz M.; Takakura, Ana C.; Moreira, Thiago S.; Schultz, Harold D.; Marcus, Noah J.; Alcayaga, Julio; Del Rio, Rodrigo (PORTLAND PRESS LTD, 2019)
      Activation of the sympathetic nervous system is a hallmark of heart failure (HF) and is positively correlated with disease progression. Catecholaminergic (C1) neurons located in the rostral ventrolateral medulla (RVLM) are ...
    • Aboveground biomass estimation in intervened and non-intervened Nothofagus pumilio forests using remotely sensed data 

      Pena, Marco [Chile. Universidad Mayor]; Schmidt, Andreas [Alemania. University of Munster]; Schmidt, Harald [Universidad de Chile]; Schulte, Andreas [Alemania. University of Munster] (CIENCIAS, 2012)
      Forest inventory data can be used along with remotely sensed data to estimate biomass and carbon stocks over large and inaccessible forested areas. In this study, the relationship between satellite-derived multispectral ...
    • Abrogation of Stem Loop Binding Protein (Slbp) function leads to a failure of cells to transition from proliferation to differentiation, retinal coloboma and midline axon guidance deficits 

      Valdivia, Leonardo E. [Univ Mayor, Fac Ciencias, Ctr Integrat Biol, Santiago, Chile]; Turner, Katherine J.; Hoyle, Jacqueline; Cerveny, Kara L.; Hart, Wendy; Mangoli, Maryam; Geisler, Robert; Rees, Michele; Houart, Corinne; Poole, Richard J.; Wilson, Stephen W.; Gestri, Gaia (PUBLIC LIBRARY SCIENCE, 2019)
      Through forward genetic screening for mutations affecting visual system development, we identified prominent coloboma and cell-autonomous retinal neuron differentiation, lamination and retinal axon projection defects in ...
    • Acceso, tiempo y propósito de uso de tecnologías digitales en estudiantes de pedagogía chilenos 

      Cerda C., Saiz J.L., Villegas L.; León, Miriam [Escuela de Psicología, Facultad de Ciencias, Universidad Mayor. Chile] (Facultad de Filosofía y Humanidades, Universidad Austral de Chile, 2018)
      Esta investigación tuvo por objetivo describir el acceso, tiempo y propósito de uso (académico, recreativo y social) de tecnologías digitales en estudiantes de pedagogía chilenos. Se examinó, además, si ser usuario académico ...
    • Acido úrico ¿un nuevo factor contribuyente al desarrollo de obesidad? 

      Valenzuela M., Alex [Chile. Universidad Mayor. Escuela de Nutrición y Dietética] (Facultad de Ciencias, 2016)
      El exceso de ácido úrico es reconocido como un factor de riesgo para diversas enfermedades metabólicas, incluyendo: gota, urolitiasis, diabetes tipo 2, hipertensión arterial, síndrome metabólico y enfermedad cardiovascular. ...
    • Activating PTEN Tumor Suppressor Expression with the CRISPR/dCas9 System 

      Garcia-Bloj, Benjamín [Univ Mayor, Sch Med, Fac Sci]; Moses, Colette; Nugent, Fiona; Waryah, Charlene Babra; Harvey, Alan R.; Blancafort, Pilar (CELL PRESS, 2019)
      PTEN expression is lost in many cancers, and even small changes in PTEN activity affect susceptibility and prognosis in a range of highly aggressive malignancies, such as melanoma and triple-negative breast cancer (TNBC). ...
    • Actividad antifúngica de melanina en cepas clínicas de Candida spp. 

      Fuentes, Marisol [Chile. Universidad Mayor. Escuela de Tecnología Médica]; Tapia, Cecilia V. [Chile. Universidad Mayor. Escuela de Tecnología Médica]; Alburquenque, Claudio [Chile. Universidad Mayor. Escuela de Tecnología Médica]; Falconer, Mary A. [Chile. Universidad Mayor. Escuela de Tecnología Médica]; Amaro, José [Chile. Universidad Mayor. Escuela de Tecnología Médica]; Gordillo, Diego [Chile. Universidad Mayor. Escuela de Tecnología Médica]; Hernández, Romané [Chile. Universidad Mayor. Escuela de Tecnología Médica] (Facultad de Ciencias, 2014)
      Introducción: Los melanocitos son células presentes en piel y en mucosas que sintetizan melanina, además de citoquinas. Es sabido que melanina presenta actividad antimicrobiana y que los melanocitos se melanizan al ser ...
    • Actividad antifúngica y perfil de seguridad del producto natural derivado del aceite de maravilla ozonizado (AMO3) en dermatofitos 

      Anticevic C., Sonia [Universidad de Chile]; Rodríguez B., Héctor [Universidad de Chile]; Silva V., Víctor [Chile. Universidad Mayor. Facultad de Medicina] (CIENCIAS, 2011)
      Se evaluó la seguridad y actividad antifúngica del aceite de maravilla ozonizado (AMO3) frente a dermatofitos. AMO3 se generó a través de un proceso original que implica modificación del aceite previa ozonización por ...
    • Actualizaciones sobre "Irisina": la nueva mioquina 

      Trujillo G., Luz María [Chile. Universidad Diego Portales. Facultad de Medicina]; von Oetinger G., Astrid [Chile. Universidad Andrés Bello. Facultad de Ciencias de la Rehabilitación]; García L., Daniela [Chile. Universidad Mayor] (Facultad de Ciencias, 2016)
      En la búsqueda continua de los investigadores por combatir de manera más efectiva la obesidad, se descubre una mioquina llamada Irisina. La Irisina es secretada principalmente por el músculo esquelético en respuesta al ...
    • Adaptation to milking agropastoralism in Chilean goat herders and nutritional benefit of lactase persistence 

      Montalva, Nicolás [Univ Mayor, Soc & Hlth Res Ctr, Santiago, Chile]; Adhikari, Kaustubh; Liebert, Anke; Mendoza-Revilla, Javier; Flores, Sergio V.; Mace, Ruth; Swallow, Dallas M. (WILEY, 2019)
      The genetic trait of lactase persistence (LP) evolved as an adaptation to milking pastoralism in the Old World and is a well-known example of positive natural selection in humans. However, the specific mechanisms conferring ...
    • Adherence to physical activity recommendations across age categories: Findings from the 2009-2010 Chilean National Health Survey 

      Celis-Morales, Carlos [Univ Mayor, CIFE, Santiago, Chile]; Garrido-Méndez, Alex; Concha-Cisrnas, Yeny; Rocha, Fanny Petermann; Díaz-Martínez, Ximena; María Leiva, Ana; Troncoso, Claudia; Adela Martínez, Maria; Salas-Bravo, Arlos; Alvarez, Cristián; Ramírez-Campillo, Rodrigo; Cristi-Montero, Carlos; Rodríguez, Fernando; Iturra-González, Lose A. (SOC CHILENA NUTRICION, BROMATOLOGIA & TOXICOLOGIA, 2019)
      Although physical activity (PA) is a protective factor against non-communicable diseases, there is an important proportion of the population who do not meet PA guidelines. Our aim was to investigate how adherence to PA ...
    • Adherencia al tratamiento en adolescentes diabéticos tipo 1 chilenos: una aproximación psicológica 

      Ortiz, Eugenia [Pontificia Universidad Católica de Chile] (CIENCIAS, 2005)
      Background: Treatment compliance among patients with type 1 diabetes mellitus, is low in 50% of diabetic teenagers, becoming a social and medical problem. Aim: To determine psycho-social factors associated to treatment ...
    • Adiposity, healthy lifestyle and physical activity levels in housewives and women with paid employment in Chile 

      Celis-Morales, Carlos [Univ Mayor, CIFE, Santiago, Chile]; Concha-Cisternas, Yeny; Petermann-Rocha, Fanny; Vásquez-Gómez, Jaime A.; Matus-Castillo, Carlos; María Leiva, Ana; Adela Martínez, Maria; Garrido-Méndez, Alex; Díaz-Martínez, Ximena; Molina-Sotomayor, Edgardo; Pavez-Adasme, Gustavo; Carrasco Beltran, Hernaldo; Silva-Urra, Jaime; Rosa Beltran, Ana (SOC CHILENA NUTRICION, BROMATOLOGIA & TOXICOLOGIA, 2019)
      Lifestyle behaviours among women who take care of their home duties (housewives) and women who are currently working in paid employment is unknown in the Chilean population. The aim of this study was, therefore, to ...