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Signal peptide recognition in Trypanosoma cruzi GP82 adhesin relies on its localization at protein N-terminus
(NATURE PUBLISHING GROUP, 2019)
Trypanosoma cruzi, the causative agent of Chagas disease, has a dense coat of GPI-anchored virulence factors. T. cruzi GPI-anchored adhesin GP82 is encoded by a repertoire of transcripts containing several in-frame initiation ...
Pleione: A tool for statistical and multi-objective calibration of Rule-based models
(NATURE PUBLISHING GROUP, 2019)
Mathematical models based on Ordinary Differential Equations (ODEs) are frequently used to describe and simulate biological systems. Nevertheless, such models are often difficult to understand. Unlike ODE models, Rule-Based ...