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DEF8 and Autophagy-Associated Genes are Altered in Mild Cognitive Impairment, Probable Alzheimer’s Disease Patients and a Transgenic Model of the Disease
(IOS Press, 2021-02-19)
Background:Disturbances in the autophagy/endolysosomal systems are proposed as early signatures of Alzheimer’s disease (AD). However, few studies are available concerning autophagy gene expression in AD patients. Objective:To ...
Levels of low-molecular-weight hyaluronan in periodontitis-treated patients and its immunostimulatory effects on CD4+ T lymphocytes
(SPRINGER HEIDELBERG, 2021-02-26)
Objectives During periodontitis, chronic inflammation triggers soft tissue breakdown, and hyaluronan is degraded into fragments of low molecular weight (LMW-HA). This investigation aimed to elucidate whether LMW-HA fragments ...
TGA class II transcription factors are essential to restrict oxidative stress in response to UV-B stress in Arabidopsis
(OXFORD UNIV PRESS, 2021-02-27)
Plants possess a robust metabolic network for sensing and controlling reactive oxygen species (ROS) levels upon stress conditions. Evidence shown here supports a role for TGA class II transcription factors as critical ...
Multiplex TaqMan Real-Time PCR Assay for Sensitive Detection of Two Weevil Species (Coleoptera: Curculionidae)
(OXFORD UNIV PRESS INC, 2021-06-04)
Rapid and cost-efficient identification of Naupactus species is becoming a key process for the exportation of citrus fruit from Chile and other countries, considering the quarantine regulations for some species of the ...
SinEx DB 2.0 update 2020: database for eukaryotic single-exon coding sequences
(Oxford University Press, 2021-01-28)
Single-exon coding sequences (CDSs), also known as 'single-exon genes' (SEGs), are defined as nuclear, protein-coding genes that lack introns in their CDSs. They have been studied not only to determine their origin and ...
Metabolite Fruit Profile Is Altered in Response to Source-Sink Imbalance and Can Be Used as an Early Predictor of Fruit Quality in Nectarine
(FRONTIERS MEDIA SA, 2021-01-08)
Peaches and nectarines [Prunus persica (L.) Batsch] are among the most exported fresh fruit from Chile to the Northern Hemisphere. Fruit acceptance by final consumers is defined by quality parameters such as the size, ...
Development of a Multiplex PCR Assay for Genotyping the Fish Pathogen Piscirickettsia salmonis Through Comparative Genomics
(FRONTIERS MEDIA SA, 2021-07-11)
Piscirickettsia salmonis is a bacterial pathogen that severely impact the aquaculture in several countries as Canada, Scotland, Ireland, Norway, and Chile. It provokes Piscirickettsiosis outbreaks in the marine phase of ...
A decade later, reviewing floating marine debris in Northern Chilean Patagonia
(PERGAMON-ELSEVIER SCIENCE LTD, 2021-07-07)
Floating marine debris (FMD) were abundantly reported in the Northern Chilean Patagonia in 2009 where seabased activities (mussel and salmon aquaculture) are responsible for most of them. Identifying the sources of FMD is ...
ConnecTF: A platform to integrate transcription factor-gene interactions and validate regulatory networks
(OXFORD UNIV PRESS INC, 2021-04-28)
Deciphering gene regulatory networks (GRNs) is both a promise and challenge of systems biology. The promise lies in identifying key transcription factors (TFs) that enable an organism to react to changes in its environment. ...
Filtering of Data-Driven Gene Regulatory Networks Using Drosophila melanogaster as a Case Study
(FRONTIERS MEDIA SA, 2021-07-28)
Gene Regulatory Networks (GRNs) allow the study of regulation of gene expression of whole genomes. Among the most relevant advantages of using networks to depict this key process, there is the visual representation of large ...