• A case report of a primary synovial chondromatosis of temporomandibular joint, producing medial displacement of the articular disc. 

      Droguett, C. [Chile. Universidad Mayor]; Fumeaux, JE [Chile. Universidad Mayor]; Skármeta, Nicolás Patricio [Chile. Universidad Mayor] (Facultad de Ciencias, 2014)
      Synovial chondromatosis in the temporomandibular joint (TMJ) is a rare benign cartilaginous metaplasia characterized by the formation of loose bodies within the synovial joint space. This condition presents a specific triad ...
    • ALS-linked protein disulfide isomerase variants cause motor dysfunction 

      Colombo, Alicia [Universidad de Chile]; Saaranen, Mirva J. [Finlandia. University of Oulu. Biocenter Oulu and Faculty of Biochemistry and Molecular Medicine]; Pérez, Viviana [Chile. Universidad de Concepción]; Ojeda, Jorge [Chile. Universidad de Concepción]; Bustos, Fernando J. [Chile. Universidad Andrés Bello] (CIENCIAS, 2016)
      Disturbance of endoplasmic reticulum (ER) proteostasis is a common feature of amyotrophic lateral sclerosis (ALS). Protein disulfide isomerases (PDIs) are ER foldases identified as possible ALS biomarkers, as well as ...
    • Alterations in type i hemidesmosome components suggestive of epigenetic control in the salivary glands of patients with Sjogren's syndrome 

      González, Sergio Miguel [Chile. Universidad Mayor. Facultad de Odontología]; Aguilera, Sergio [s.af]; Alliende, Cecilia [s.af]; Urzúa, Ulises [Universidad de Chile. Facultad de Medicina]; Quest, Andrew FG [Universidad de Chile. Facultad de Medicina]; Herrera, Luisa [s.af]; Hermoso, Marcela A. [Universidad de Chile. Facultad de Medicina]; Brito, Mónica [Chile. Universidad Mayor. Escuela de Tecnología Médica]; Leyton, Cecilia [s.af]; González, María Julieta [s.af]; Pérez, Paola Jacqueline [National Institutes of Health]; Ewert, Patricia; Molina, Claudio [Chile. Universidad San Sebastián]; Romo, Rafael [s.af] (Facultad de Ciencias, 2011)
      Objective. Acinar cells in the salivary glands of patients with Sjo¨gren’s syndrome (SS) display severe alterations in anchorage to the basal lamina. Bioinformatics analysis of the BP230 gene sequence has revealed the ...
    • BarR, an Lrp-type transcription factor in sulfolobus acidocaldarius, regulates an aminotransferase gene in a β-alanine responsive manner. 

      Liu, Han [Vrije Universiteit Brussel. Research Group of Microbiology, Department of Bio-engineering Sciences]; Peeters, Eveline [Chile. Universidad Mayor. Centro de Genómica y Bioinformática]; Charlier, Daniel [Vrije Universiteit Brussel. Research Group of Microbiology, Department of Bio-engineering Sciences]; Albers, Sonja‐Verena [Max Planck Institute for Terrestrial Microbiology]; Bernander,Rolf [Stockholm University]; Ann‐Christin, Lindås [Stockholm University]; van Wolferen, Marleen [Max Planck Institute for Terrestrial Microbiology]; Maes, Dominique [Vrije Universiteit Brussel. Research Group of Microbiology, Department of Bio-engineering Sciences]; Orell, Alvaro [Max Planck Institute for Terrestrial Microbiology] (Facultad de Ciencias, 2014)
      In archaea, nothing is known about the β-alanine degradation pathway or its regulation. In this work, we identify and characterize BarR, a novel Lrp-like transcription factor and the first one that has a non-proteinogenic ...
    • “Candidatus Neoehrlichia chilensis” sp. nov.: Molecular detection and characterization of a novel Anaplasmataceae in wild rodents from Valdivia, southern Chile 

      Muller, A. [Chile. Universidad Austral de Chile. Facultad de Ciencias Veterinarias]; Otth, C. [Chile. Universidad Austral de Chile. Facultad de Medicina]; Sepúlveda, P. [Chile. Universidad Austral de Chile. Facultad de Ciencias Veterinarias]; Monti, G. [Chile. Universidad Austral de Chile. Facultad de Ciencias Veterinarias]; Bittencourt, P. [Chile. Universidad Mayor. Escuela de Medicina Veterinaria]; Nachum Biala, Y. [Israel. The Hebrew University of Jerusalem. Koret School of Veterinary Medicine]; Gutiérrez, R. [Israel. The Hebrew University of Jerusalem. Koret School of Veterinary Medicine]; Harrus, S. [Israel. The Hebrew University of Jerusalem. Koret School of Veterinary Medicine] (Chile. Universidad Mayor, 2018-04)
      This study aimed to screen wild rodents from southern Chile, for the presence of Anaplasmatacea. Spleen samples from 33 wild rodents trapped in Valdivia Province were screened by conventional PCR (cPCR), targeting the ...
    • Changes in Rab3D Expression and Distribution in the Acini of Sjogren's Syndrome Patients Are Associated With Loss of Cell Polarity and Secretory Dysfunction 

      Albornoz, Amelina [Universidad de Chile]; Aguilera, Sergio [Chile. Clínica INDISA]; Alliende, Cecilia [Universidad de Chile]; Molina,Claudio [Chile. Universidad Mayor]; Castro, Isabel [Universidad de Chile]; Urzua,Ulises [Universidad de Chile] (CIENCIAS, 2011)
      OBJECTIVE: Oral and ocular dryness are frequent and serious symptoms of Sjögren's syndrome (SS) that reflect problems in secretion due to glandular dysfunction. Exocytosis, an important process in the secretory pathway, ...
    • Electromyographic adjustments during continuous and intermittent incremental fatiguing cycling 

      Martinez-Valdes, E. [University of Potsdam]; Guzman-Venegas, R.A. [Chile. Universidad de Los Andes. Escuela de Kinesiología]; Silvestre, R.A. [Chile. Universidad Mayor. Escuela de Kinesiología]; Macdonald, J.H. [Bangor University. School of Sport, Health and Exercise Sciences]; Falla, D. [Alemania. University Medical Center, Göttingen]; Araneda, O.F. [Chile. Universidad de Los Andes. Escuela de Kinesiología]; Haichelis, D. [Chile. Universidad Santo Tomás. Instituto de Ciencias del Ejercicio] (Facultad de Ciencias, 2015)
      We studied the sensitivity of electromyographic (EMG) variables to load and muscle fatigue during continuous and intermittent incremental cycling. Fifteen men attended three laboratory sessions. Visit 1: lactate threshold, ...
    • Insect abundance and damage on the deciduous Nothofagus macrocarpa increase with altitude at a site in the Mediterranean climate zone of Chile 

      Claros, Sandra [Chile. Universidad Mayor] (CIENCIAS, 2015)
      An understanding of the spatial and temporal patterns of insect abundance and plant damage across altitudinal gradients and the mechanisms driving them is limited. Importantly, little is known in this area in relation to ...
    • Longitudinal analysis of metalloproteinases, tissue inhibitors of metalloproteinases and clinical parameters in gingival crevicular fluid from periodontitis-affects patients 

      Valenzuela, M. A [Universidad de Chile]; Melej, C. [Chile. Universidad de Antofagasta]; Zaldivar, M. [Universidad de Chile]; Puente, J. [Universidad de Chile]; Martinez, Benjamín [Chile. Universidad Mayor] (CIENCIAS, 2005)
      BACKGROUND: The aim of this work was to improve the assessment of the periodontal disease status through measurements of extracellular matrix metalloproteinases (MMPs) and their tissular inhibitors (TIMPs) in the gingival ...
    • MMP-13 and TIMP-1 determinations in progressive chronic periodontitis 

      Martínez,Benjamin [Chile. Universidad Mayor] (CIENCIAS, 2007)
      Matrix metalloproteinase (MMP)-13 is a collagenase involved in extracellular matrix degradation either by its direct degradative effects or by processing bioactive substrates. The aim of this study was to determine the ...
    • MUC1/SEC and MUC1/Y overexpression is associated with inflammation in Sjogren's syndrome 

      Castro, I [Universidad de Chile]; González, S. [Chile. Universidad Mayor]; Aguilera, S. [Chile. Clínica INDISA]; Molina, C. [Chile. Universidad Mayor] (CIENCIAS, 2015)
      Objectives: To evaluate the expression and localization of MUC1/SEC and MUC1/Y isoforms in labial salivary glands (LSG) from Sjögren's syndrome patients (SS patients), as well as their in vitro expression induced by ...
    • Multiple macrodontic multituberculism 

      Martínez R., Benjamín [Chile. Universidad Mayor. Escuela de Odontología]; Fariña S., Rodrigo [Chile. Universidad Mayor. Escuela de Odontología]; Gorlin, Robert J. [University of Minnesota. School of Dentistry] (CIENCIAS, 2003)
      Ekman-Westborg and Julin [1974: Oral Surg 38:217-222], described multiple macrodontia and multituberculism affecting the teeth without other anomalies (E-WJ). We describe a Chilean case in a 12-year-old with the typical ...
    • Oral manifestations and their treatment in Sjogren's syndrome 

      Sung, H [Universidad de Chile]; Sepúlveda, D. [Universidad de Chile]; González, M. J. [Universidad de Chile]; Molina, C. [Chile. Universidad Mayor] (CIENCIAS, 2014)
      Sjögren's syndrome (SS) is a complex, chronic, systemic, autoimmune disease that mainly affects the exocrine glands, especially the salivary and lacrimal glands, leading to dryness of the oral and ocular mucosae. Several ...
    • Origin of axonal proteins: Is the axon-schwann cell unit a functional syncytium? 

      Alvarez, Jaime [Chile. Universidad Mayor. Facultad de Ciencias]; Court, Felipe A. [Chile. Universidad Mayor. Facultad de Ciencias] (CIENCIAS, 2016)
      The structural homeostasis is challenging for neurons, whose axons extend up to meters in large animals, and the axoplasmic mass reaches over a thousand times that of the cell body. Thus, the protein demand may overcome ...
    • Prevalence of clinical attachment loss in adolescents in Santo Domingo, Dominican Republic 

      Carpio, Ana Maria [República Dominicana. Universidad Católica de Santo Domingo]; Bobadilla, Mónica [Dominican Republic.Catholic University, Santo Domingo]; Reyes, Raysa [República Dominicana. School Programme Colgate Palmolive]; Guzmán, Isabel [Colombia. Universidad de Medellín]; Martinez, Benjamín [Chile. Universidad Mayor]; Gamonal, Jorge [Universidad de Chile] (CIENCIAS, 2005)
      Background: Data on periodontal conditions in adolescents in the Dominican Republic are scarce. The aim of the present crosssectional study was to estimate the prevalence of periodontal attachment loss among Dominican ...
    • Routine Prophylaxes Every 3 Months Improves Chronic Periodontitis Status in Type 2 Diabetes 

      Quintero, Antonio [Chile.Universidad de los Andes]; Casanova, Patricia A [Chile. Universidad Mayor]; Martínez, Benjamín [Chile. Universidad Mayor] (CIENCIAS, 2014)
      Background: Periodontitis and type 2 diabetes mellitus (T2DM) are major health problems, especially in low‐income populations with little access to dental care. Low‐cost models for treatment of periodontal disease have not ...


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