• A Carbohydrate Moiety of Secreted Stage-Specific Glycoprotein 4 Participates in Host Cell Invasion by Trypanosoma cruzi Extracellular Amastigotes 

      Cordero, Esteban M. [Univ Mayor, Ctr Genom & Bioinformat, Fac Ciencias, Santiago, Chile]; Florentino, Pilar T. V.; Real, Fernando; Orikaza, Cristina M.; da Cunha, Julia P. C.; Vitorino, Francisca N. L.; Sobreira, Tiago J. P.; Mortara, Renato A. (FRONTIERS MEDIA SA, 2018)
      Trypanosoma cruzi is the etiologic agent of Chagas' disease. It is known that amastigotes derived from trypomastigotes in the extracellular milieu are infective in vitro and in vivo. Extracellular amastigotes (EAs) have a ...
    • Arbuscular mycorrhizae and absence of cluster roots in the Brazilian Proteaceae Roupala montana Aubl. 

      Miyasaka de Almeida, Andrea [Univ Mayor, Ctr Genom & Bioinformat, Fac Ciencias]; Coutinho Detmann, Kelly da Silva; Leite, Tiago de Souza; de Oliveira Neto, Ricardo Rodrigues; Delgado, Marina Neves; Alcoforado Rebello, Vitor Paiva; Azevedo, Aristea Alves; Megumi Kasuya, María Catarina; Selosse, Marc-Andre (SPRINGER, 2019)
      Plants growing on soils poor in phosphorus (P) develop P-acquisition strategies such as symbiotic associations with arbuscular mycorrhizal fungi (AMF). In very poor soils, cluster roots, a non-symbiotic alternative strategy ...
    • Distinctive Archaeal Composition of an Artisanal Crystallizer Pond and Functional Insights Into Salt-Saturated Hypersaline Environment Adaptation 

      Trefault, Nicole [Univ Mayor, GEMA Ctr Genom Ecol & Environm, Santiago, Chile]; Plominsky, Alvaro M.; Henriquez-Castillo, Carlos; Delherbe, Nathalie; Podell, Sheila; Ramírez-Flandes, Salvador; Ugalde, Juan A.; Santibañez, Juan F.; van den Engh, Ger; Hanselmann, Kurt; Ulloa, Osvaldo; De la Iglesia, Rodrigo; Allen, Eric E. (FRONTIERS MEDIA SA, 2018)
      Hypersaline environments represent some of the most challenging settings for life on Earth. Extremely halophilic microorganisms have been selected to colonize and thrive in these extreme environments by virtue of a broad ...
    • Draft Genome Sequences of 40 Pathogenic Leptospira Strains Isolated from Cattle in Uruguay 

      Iraola, Gregorio [Univ Mayor, Ctr Integrat Biol, Santiago, Chile]; Nieves, Cecilia; Ferres, Ignacio; Díaz-Viraque, Florencia; Buschiazzo, Alejandro; Zarantonelli, Leticia (AMER SOC MICROBIOLOGY, 2019)
      Pathogenic Leptospira species represent a major concern for livestock but also for human health, as they cause zoonotic infections. Forty strains representing L. interrogans, L. borgpetersenii, and L. noguchii were isolated ...
    • Effect of CO2 Concentration on Uptake and Assimilation of Inorganic Carbon in the Extreme Acidophile Acidithiobacillus ferrooxidans 

      Holmes, David S.[Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Santiago, Chile]; Esparza, Mario; Jedlicki, Eugenia; González, Carolina; Dopson, Mark (FRONTIERS MEDIA SA, 2019)
      This study was motivated by surprising gaps in the current knowledge of microbial inorganic carbon (Ci) uptake and assimilation at acidic pH values (pH < 3). Particularly striking is the limited understanding of the ...
    • Essential Oil, Extracts, and Sesquiterpenes Obtained From the Heartwood of Pilgerodendron uviferum Act as Potential Inhibitors of the Staphylococcus aureus NorA Multidrug Efflux Pump 

      Sanhueza, Loreto; Muñoz, Patricia [Univ Mayor, Fac Estudios Interdisciplinarios, Nucleo Quim & Bioquim, Santiago, Chile]; Espinoza, Javier; Urzua, Alejandro; Walter, Mariana; Fincheira, Paola; Muñoz, Patricia; Mendoza, Leonora; Wilkens, Marcela (FRONTIERS MEDIA SA, 2019)
      Staphylococcus aureus is a serious human pathogen that is highly adaptive to environmental conditions and rapidly develops antibiotic resistance. The use of efflux pumps to reduce antibiotic concentrations at the intracellular ...
    • First Release of the Bacterial Biobank of the Urban Environment (BBUE) 

      Iraola, Gregorio [Univ Mayor, Ctr Biol Integrat, Santiago, Chile]; Antelo, Veronica; Betancor, Laura; Barcala, María Victoria; Miguez, Diana; Gonnet, Gaston H. (AMER SOC MICROBIOLOGY, 2018)
      Metagenomics is providing a broad overview of bacterial functional diversity; however, culturing and biobanking are still essential for microbiology. Here, we present the Bacterial Biobank of the Urban Environment (BBUE), ...
    • Global phylogeography and ancient evolution of the widespread human gut virus crAssphage 

      Trefault, Nicole [Univ Mayor, GEMA Ctr Genom Ecol & Environm, Huechuraba, Chile]; Edwards, Robert A.; Vega, Alejandro A.; Norman, Holly M.; Ohaeri, Maria; Levi, Kyle; Dinsdale, Elizabeth A.; Cinek, Ondrej; Aziz, Ramy K.; McNair, Katelyn; Barr, Jeremy J.; Bibby, Kyle; Brouns, Stan J. J.; Cazares, Adrian; de Jonge, Patrick A.; Desnues, Christelle; Díaz Muñoz, Samuel L.; Fineran, Peter C.; Kurilshikov, Alexander; Lavigne, Rob; Mazankova, Karla; McCarthy, David T.; Nobrega, Franklin L.; Reyes Muñoz, Alejandro; Tapia, German; Trefault, Nicole; Tyakht, Alexander, V; Vinuesa, Pablo; Wagemans, Jeroen; Zhernakova, Alexandra; Aarestrup, Frank M.; Ahmadov, Gunduz; Alassaf, Abeer; Anton, Josefa; Asangba, Abigail; Billings, Emma K.; Cantu, Vito Adrian; Carlton, Jane M.; Cazares, Daniel; Cho, Gyu-Sung; Condeff, Tess; Cortés, Pilar; Cranfield, Mike; Cuevas, Daniel A.; De la Iglesia, Rodrigo; Decewicz, Przemyslaw; Doane, Michael P.; Dominy, Nathaniel J.; Dziewit, Lukasz; Elwasila, Bashir Mukhtar; Murat Eren, A.; Franz, Charles; Fu, Jingyuan; Garcia-Aljaro, Cristina; Ghedin, Elodie; Gulino, Kristen M.; Haggerty, John M.; Head, Steven R.; Hendriksen, Rene S.; Hill, Colin; Hyoty, Heikki; Ilina, Elena N.; Irwin, Mitchell T.; Jeffries, Thomas C.; Jofre, Juan; Junge, Randall E.; Kelley, Scott T.; Mirzaei, Mohammadali Khan; Kowalewski, Martin; Kumaresan, Deepak; Leigh, Steven R.; Lipson, David; Lisitsyna, Eugenia S.; Llagostera, Montserrat; Maritz, Julia M.; Marr, Linsey C.; McCann, Angela; Molshanski-Mor, Shahar; Monteiro, Silvia; Moreira-Grez, Benjamin; Morris, Megan; Mugisha, Lawrence; Muniesa, Maite; Neve, Horst; Nam-phuong Nguyen; Nigro, Olivia D.; Nilsson, Anders S.; O'Connell, Taylor; Odeh, Rasha; Oliver, Andrew; Piuri, Mariana; Prussin, Aaron J., II; Qimron, Udi; Quan, Zhe-Xue; Rainetova, Petra; Ramírez-Rojas, Adan; Raya, Raul; Reasor, Kim; Rice, Gillian A. O.; Rossi, Alessandro; Santos, Ricardo; Shimashita, John; Stachler, Elyse N.; Stene, Lars C.; Strain, Ronan; Stumpf, Rebecca; Torres, Pedro J.; Twaddle, Alan; Ibekwe, MaryAnn Ugochi; Villagra, Nicolás; Wandro, Stephen; White, Bryan; Whiteley, Andy; Whiteson, Katrine L.; Wijmenga, Cisca; Zambrano, María M.; Zschach, Henrike; Dutilh, Bas E. (NATURE PUBLISHING GROUP, 2019)
      Microbiomes are vast communities of microorganisms and viruses that populate all natural ecosystems. Viruses have been considered to be the most variable component of microbiomes, as supported by virome surveys and examples ...
    • Identification and Unusual Properties of the Master Regulator FNR in the Extreme Acidophile Acidithiobacillus ferrooxidans 

      Holmes, David S. [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Santiago, Chile]; Osorio, Hector; Mettert, Erin; Kiley, Patricia; Dopson, Mark; Jedlicki, Eugenia (FRONTIERS MEDIA SA, 2019)
      The ability to conserve energy in the presence or absence of oxygen provides a metabolic versatility that confers an advantage in natural ecosystems. The switch between alternative electron transport systems is controlled ...
    • Immunocytochemical and Ultrastructural Evidence Supporting That Andes Hantavirus (ANDV) Is Transmitted Person-to-Person Through the Respiratory and/or Salivary Pathways 

      Zaror, Luis [Univ Mayor, Escuela Tecnol Med, Temuco, Chile]; Pizarro, Enrique; Navarrete, Maritza; Méndez, Carolina; Mansilla, Carlos; Tapia, Mauricio; Carrasco, Cristián; Salazar, Paula; Murua, Roberto; Padula, Paula; Otth, Carola; Martin Rodríguez, Esteban (FRONTIERS MEDIA SA, 2020)
      In South America Andes hantavirus (ANDV) is hosted by the rodent Oligoryzomys longicaudatus (also known as pygmy rice rat). In humans, ANDV causes Hantavirus Pulmonary Syndrome (HPS), with a fatality rate of about 40%. ...
    • Inhibition-Disruption of Candida glabrata Biofilms: Symmetrical Selenoesters as Potential Anti-Biofilm Agents 

      De la Cruz-Claure, María L. [Univ Mayor, Fac Ciencias Bioquim Quim Farmaceut & Biol, Fac Odontol, Santiago, Chile]; Céspedes-Llave, Ariel A.; Ulloa, María T.; Benito-Lama, Miguel; Dominguez-Alvarez, Enrique; Bastida, Agatha (MDPI, 2019)
      Candida glabrata is one of the most prevalent pathogenic Candida species in dental plaque on tooth surfaces. Candida biofilms exhibit an enhanced resistance against most antifungal agents. Thus, the development of alternative ...
    • Metabolic potential and in situ transcriptomic profiles of previously uncharacterized key microbial groups involved in coupled carbon, nitrogen and sulfur cycling in anoxic marine zones 

      Trefault, Nicole [Univ Mayor, GEMA Ctr Genom Ecol & Environm, Santiago, Chile]; Plominsky, Alvaro M.; Podell, Sheila; Blanton, Jessica M.; De la Iglesia, Rodrigo; Allen, Eric E.; von Dassow, Peter; Ulloa, Osvaldo (WILEY, 2018)
      Anoxic marine zones (AMZs) impact biogeochemical cycles at the global scale, particularly the nitrogen cycle. Key microbial players from AMZs have been identified, but the majority remains unrecognized or uncharacterized. ...
    • Pathogenomics of Emerging Campylobacter Species 

      Iraola, Gregorio [Univ Mayor, Ctr Integrat Biol, Santiago, Chile]; Costa, Daniela (AMER SOC MICROBIOLOGY, 2019)
      Campylobacter is among the four main causes of gastroenteritis worldwide and has increased in both developed and developing countries over the last 10 years. The vast majority of reported Campylobacter infections are caused ...
    • Uncovering the Mechanisms of Halotolerance in the Extremely Acidophilic Members of the Acidihalobacter Genus Through Comparative Genome Analysis 

      Holmes, David S. [Univ Mayor, Sci Life Fdn, Ctr Bioinformat & Genome Biol, Santiago, Chile]; González, Carolina [Univ Mayor, Sci Life Fdn, Ctr Bioinformat & Genome Biol, Santiago, Chile]; Khaleque, Himel N.; Shafique, Raihan; Kaksonen, Anna H.; Watkin, Elizabeth L. J. (FRONTIERS MEDIA SA, 2019)
      There are few naturally occurring environments where both acid and salinity stress exist together, consequently, there has been little evolutionary pressure for microorganisms to develop systems that enable them to deal ...
    • Urban metagenomics uncover antibiotic resistance reservoirs in coastal beach and sewage waters 

      Iraola, Gregorio [Univ Mayor, Ctr Biol Integrat, Santiago, Chile]; Fresia, Pablo; Antelo, Veronica; Salazar, Cecilia; Gimenez, Matias; D'Alessandro, Bruno; Afshinnekoo, Ebrahim; Mason, Christopher; Gonnet, Gaston H. (BMC, 2019)
      BackgroundMicrobial communities present in environmental waters constitute a reservoir for antibiotic-resistant pathogens that impact human health. For this reason, a diverse variety of water environments are being analyzed ...


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