Centro de Investigación en Genómica y Bioinformática (CGB)
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A Revised View of the LSU Gene Family: New Functions in Plant Stress Responses and Phytohormone Signaling
(MDPI, 2023-02)LSUs (RESPONSE TO LOW SULFUR) are plant-specific proteins of unknown function that were initially identified during transcriptomic studies of the sulfur deficiency response in Arabidopsis. Recent functional studies have ... -
Multi-trait and multi-environment genomic prediction for flowering traits in maize: a deep learning approach
(FRONTIERS MEDIA SA, 2023-08-01)Maize (Zea mays L.), the third most widely cultivated cereal crop in the world, plays a critical role in global food security. To improve the efficiency of selecting superior genotypes in breeding programs, researchers ... -
Editorial: Physiological, biochemical and molecular approaches in response to abiotic stresses in plants
(FRONTIERS MEDIA SA, 2023-04-21)Sin resumen. -
Phylogenomic analysis of the Porphyromonas gingivalis-Porphyromonas gulae duo: approaches to the origin of periodontitis
(FRONTIERS MEDIA SA, 2023-07-19)Porphyromonas gingivalis is an oral human pathogen associated with the onset and progression of periodontitis, a chronic immune-inflammatory disease characterized by the destruction of the teeth-supporting tissue. P. ... -
Insights into early evolutionary adaptations of the Akkermansia genus to the vertebrate gut
(FRONTIERS MEDIA SA, 2023-09-14)Akkermansia, a relevant mucin degrader from the vertebrate gut microbiota, is a member of the deeply branched Verrucomicrobiota, as well as the only known member of this phylum to be described as inhabitants of the gut. ... -
Influence of mobile genetic elements and insertion sequences in long- and short-term adaptive processes of Acidithiobacillus ferrooxidans strains
(NATURE PORTFOLIO, 2023-07-05)The recent revision of the Acidithiobacillia class using genomic taxonomy methods has shown that, in addition to the existence of previously unrecognized genera and species, some species of the class harbor levels of ... -
Whole-exome sequencing of oral epithelial dysplasia samples reveals an association with new genes
(SOCIEDADE BRASILEIRA DE PESQUISA ODONTOLOGICA, 2023-03-23)The genetic basis of oral epithelial (OED) is unknown, and there is no reliable method for evaluating the risk of malignant transformation. Somatic mutations are responsible for the transformation of dysplastic mucosa to ... -
Comparative genomics sheds light on transcription factor-mediated regulation in the extreme acidophilic Acidithiobacillia representatives
(Elsevier Masson s.r.l., 2024-01)Extreme acidophiles thrive in acidic environments, confront a multitude of challenges, and demonstrate remarkable adaptability in their metabolism to cope with the ever-changing environmental fluctuations, which encompass ... -
Anaerobic RSH-dependent tellurite reduction contributes to Escherichia coli tolerance against tellurite
(SOC BIOLGIA CHILE, 2022-03)Background Tellurium is a rare metalloid that exerts high toxicity on cells, especially on bacteria, partly due to reactive oxygen species (ROS) generation. Moreover, it has also been observed that tellurite can target ... -
Development of a Multiplex PCR Assay for Genotyping the Fish Pathogen Piscirickettsia salmonis Through Comparative Genomics
(FRONTIERS MEDIA SA, 2021-07-11)Piscirickettsia salmonis is a bacterial pathogen that severely impact the aquaculture in several countries as Canada, Scotland, Ireland, Norway, and Chile. It provokes Piscirickettsiosis outbreaks in the marine phase of ... -
TGA class II transcription factors are essential to restrict oxidative stress in response to UV-B stress in Arabidopsis
(OXFORD UNIV PRESS, 2021-02-27)Plants possess a robust metabolic network for sensing and controlling reactive oxygen species (ROS) levels upon stress conditions. Evidence shown here supports a role for TGA class II transcription factors as critical ... -
Metabolite Fruit Profile Is Altered in Response to Source-Sink Imbalance and Can Be Used as an Early Predictor of Fruit Quality in Nectarine
(FRONTIERS MEDIA SA, 2021-01-08)Peaches and nectarines [Prunus persica (L.) Batsch] are among the most exported fresh fruit from Chile to the Northern Hemisphere. Fruit acceptance by final consumers is defined by quality parameters such as the size, ... -
Filtering of Data-Driven Gene Regulatory Networks Using Drosophila melanogaster as a Case Study
(FRONTIERS MEDIA SA, 2021-07-28)Gene Regulatory Networks (GRNs) allow the study of regulation of gene expression of whole genomes. Among the most relevant advantages of using networks to depict this key process, there is the visual representation of large ... -
SinEx DB 2.0 update 2020: database for eukaryotic single-exon coding sequences
(Oxford University Press, 2021-01-28)Single-exon coding sequences (CDSs), also known as 'single-exon genes' (SEGs), are defined as nuclear, protein-coding genes that lack introns in their CDSs. They have been studied not only to determine their origin and ... -
Levels of low-molecular-weight hyaluronan in periodontitis-treated patients and its immunostimulatory effects on CD4+ T lymphocytes
(SPRINGER HEIDELBERG, 2021-02-26)Objectives During periodontitis, chronic inflammation triggers soft tissue breakdown, and hyaluronan is degraded into fragments of low molecular weight (LMW-HA). This investigation aimed to elucidate whether LMW-HA fragments ... -
ConnecTF: A platform to integrate transcription factor-gene interactions and validate regulatory networks
(OXFORD UNIV PRESS INC, 2021-04-28)Deciphering gene regulatory networks (GRNs) is both a promise and challenge of systems biology. The promise lies in identifying key transcription factors (TFs) that enable an organism to react to changes in its environment. ... -
A decade later, reviewing floating marine debris in Northern Chilean Patagonia
(PERGAMON-ELSEVIER SCIENCE LTD, 2021-07-07)Floating marine debris (FMD) were abundantly reported in the Northern Chilean Patagonia in 2009 where seabased activities (mussel and salmon aquaculture) are responsible for most of them. Identifying the sources of FMD is ... -
Multiplex TaqMan Real-Time PCR Assay for Sensitive Detection of Two Weevil Species (Coleoptera: Curculionidae)
(OXFORD UNIV PRESS INC, 2021-06-04)Rapid and cost-efficient identification of Naupactus species is becoming a key process for the exportation of citrus fruit from Chile and other countries, considering the quarantine regulations for some species of the ... -
Non-Specific Antibodies Induce Lysosomal Activation in Atlantic Salmon Macrophages Infected by Piscirickettsia salmonis
(Frontiers Media S.A., 2020-11)Piscirickettsia salmonis, an aggressive intracellular pathogen, is the etiological agent of salmonid rickettsial septicemia (SRS). This is a chronic multisystemic disease that generates high mortalities and large losses ... -
In vitropropagation ofLeptocarpha rivularis, a native medicinal plant
(Springer New York, 2020-12)Leptocarpha rivularis, commonly known as "palo negro", is a species of the Astereaceae family, endemic in the forests of Southern Chile. The extracts of this plant have medicinal properties attributable to its secondary ...