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  • Association of FANCM Mutations with Familial and Early-Onset Breast Cancer Risk in a South American Population 

    Morales-Pisón, Sebastián [Univ Mayor, Ctr Oncol Precis, Chile]; Morales-González, Sarai; Fernandez-Ramires, Ricardo [Univ Mayor, Fac Med & Ciencias Salud, Chile]; Tapia, Julio C. C.; Maldonado, Edio; Calaf, Gloria M. M.; Jara, Lilian (MDPI, 2023-02)
    Breast cancer (BC) is the most common cancer among women worldwide. BRCA1/2 are responsible for 16-20% of the risk for hereditary BC. Other susceptibility genes have been identified; Fanconi Anemia Complementation Group M ...
  • Corrigendum: Unraveling patient heterogeneity in complex diseases through individualized co-expression networks: a perspective (vol 14, 1209416, 2023) 

    Latapiat, Verónica [Univ Mayor, Programa Doctorado Genom Integrat, Vicerrectoria Invest, Chile]; Sáez, Mauricio [Univ Mayor, Fac Med & Ciencias Salud, Ctr Oncol Precis, Chile]; Pedroso, Inti [Univ Mayor, Vicerrectoria Invest, Chile]; Martin, Alberto J. M. (FRONTIERS MEDIA SA, 2023-09-21)
    Sin resumen.
  • Unraveling patient heterogeneity in complex diseases through individualized co-expression networks: a perspective 

    Latapiat, Verónica [Univ Mayor, Genom Integrat, Vicerrectoria Invest, Chile]; Pedroso, Inti [Univ Mayor, Vicerrectoria Invest, Chile]; Martin, Alberto J. M.; Sáez, Mauricio [Univ Mayor, Fac Med & Ciencias Salud, Ctr Oncol Precis, Chile] (FRONTIERS MEDIA SA, 2023-08-10)
    This perspective highlights the potential of individualized networks as a novel strategy for studying complex diseases through patient stratification, enabling advancements in precision medicine. We emphasize the impact ...
  • Aging Hallmarks and the Role of Oxidative Stress 

    Maldonado, Edio; Morales-Pison, Sebastián [Univ Mayor, Fac Med & Ciencias Salud, Ctr Oncol Precis COP, Chile]; Urbina, Fabiola; Solari, Aldo (MDPI, 2023-03)
    Aging is a complex biological process accompanied by a progressive decline in the physical function of the organism and an increased risk of age-related chronic diseases such as cardiovascular diseases, cancer, and ...
  • Genome sequencing reveals molecular subgroups in oral epithelial dysplasia 

    Márquez, Agustín; Mujica, Isidora; Jordán, Natalia; Báez, Pablo; Tarquinio, Sandra; Nunes, Jean; Adorno, Daniela; Martínez, Benjamín [Univ Mayor, Fac Dent, Santiago, Chile]; Morales-Pisón, Sebastián [Univ Mayor, Precis Oncol Ctr, Santiago, Chile]; Fernández-Remires, Ricardo [Univ Mayor, Fac Med & Heatlh Sci, Santiago, Chile] (SOCIEDADE BRASILEIRA DE PESQUISA ODONTOLOGICA, 2023-07-16)
    This study aimed to analyze the molecular characteristics of oral epithelial dysplasia (OED), highlighting the pathways and variants of genes that are frequently mutated in oral squamous cell carcinoma (OSCC) and other ...
  • Planificación sanitaria a partir de los datos ómicos: ¿es posible esta idea para Chile? 

    Ríos, Juvenal A. [Univ Mayor, Fac Ciencias, Escuela Med, Ctr Oncol Precis,Inst Med Traslac, Chile]; Marcelain, Katherine; Plaza-Parrochia, Francisca; Selman, Carolina; Bustamante, Eva; Godoy, Juan A.; Labbé, Tomas P.; García-Bloj, Benjamin (Chile. Universidad Mayor, 2021-11)
    With or without a COVID19 pandemic, cancer is and will continue to be one of the greatest health challenges on the planet. In Chile, during 2016, this disease was the second cause of death in the country and during 2019, ...
  • La inhibición de los puntos de control inmunológico, una terapia en evolución: remembranza del Premio Nobel de Medicina 2018 

    Cárdenas-Oyarzo, Areli M.; Bocchieri-Oyarce, Pamela A.; Méndez-Laport, Cristian R.; Zolezzi, Juan M.; Rios, Juvenal A. [Univ Mayor, Inst Med Traslac, Ctr Oncol Precis COP, Escuela Med,Fac Ciencias, Chile] (Chile. Universidad Mayor, 2022-01)
    Professors James P. Allison and Tasuku Honjo were awarded with the 2018 Nobel Prize in Medicine for their contributions in cancer immunotherapy. The latter is a breakthrough in cancer therapy, aimed to overcome tumor-induced ...


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