New Hybrid Copper Nanoparticles/Conjugated Polyelectrolyte Composite with Antibacterial Activity
Date
2021-02Author
Jessop, Ignacio A.
Pérez, Jasmín P.
Jachura, Andrea
Núñez, Hipólito
Saldias, Cesar
Isaacs, Mauricio
Tundidor-Camba, Alain
Terraza, Claudio A.
Cárcamo-Vega, José J.
Araya-Duran, Ingrid [Univ Mayor, Fac Ciencias, Ctr Nanotecnol Aplicada, Chile]
Camarada, Maria B. [Univ Mayor, Fac Estudios Interdisciplinarios, Nucleo Quim & Bioquim, Chile]
Geographic location
Note
Tools
Abstract
In the search for new materials to fight against antibiotic-resistant bacteria, a hybrid composite from metallic copper nanoparticles (CuNPs) and a novel cationic pi-conjugated polyelectrolyte (CPE) were designed, synthesized, and characterized. The CuNPs were prepared by chemical reduction in the presence of CPE, which acts as a stabilizing agent. Spectroscopic analysis and electron microscopy showed the distinctive band of the metallic CuNP surface plasmon and their random distribution on the CPE laminar surface, respectively. Theoretical calculations on CuNP/CPE deposits suggest that the interaction between both materials occurs through polyelectrolyte side chains, with a small contribution of its backbone electron density. The CuNP/CPE composite showed antibacterial activity against Gram-positive (Staphylococcus aureus and Enterococcus faecalis) and Gram-negative (Escherichia coli and Salmonella enteritidis) bacteria, mainly attributed to the CuNPs' effect and, to a lesser extent, to the cationic CPE.
URI
https://repositorio.umayor.cl/xmlui/handle/sibum/9113https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC7865910&blobtype=pdf
https://doi.org/10.3390%2Fpolym13030401
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865910/pdf/polymers-13-00401.pdf
https://www.mdpi.com/2073-4360/13/3/401/pdf?version=1611797182
Collections
Si usted es autor(a) de este documento y NO desea que su publicación tenga acceso público en este repositorio, por favor complete el formulario aquí.