Listar por tema "Biochemistry & Molecular Biology; Chemistry, Multidisciplinary"
Mostrando ítems 1-3 de 3
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Detoxification Mechanism of 8,8-Dimethyl-3-[(R-phenyl)amino]-1,4,5(8H)-naphthalentrione Derivatives by Botrytis cinerea
(MDPI, 2019)The effect of 8,8-dimethyl-3-[(R-phenyl)amino]-1,4,5(8H)-naphthalentrione derivatives (compounds 1-13) on the mycelial growth of Botrytis cinerea was evaluated. The fungitoxic effect depended on the substituent and its ... -
Gadolinium Chloride Rescues Niemann-Pick Type C Liver Damage
(MDPI, 2018)Niemann-Pick type C (NPC) disease is a rare neurovisceral cholesterol storage disorder that arises from loss of function mutations in the NPC1 or NPC2 genes. Soon after birth, some patients present with an aggressive ... -
Structure-Activity Relationships Based on 3D-QSAR CoMFA/CoMSIA and Design of Aryloxypropanol-Amine Agonists with Selectivity for the Human 3-Adrenergic Receptor and Anti-Obesity and Anti-Diabetic Profiles
(MDPI, 2018)The wide tissue distribution of the adrenergic 3 receptor makes it a potential target for the treatment of multiple pathologies such as diabetes, obesity, depression, overactive bladder (OAB), and cancer. Currently, there ...