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    • Genome-wide circulating microRNA expression profiling reveals potential biomarkers for amyotrophic lateral sclerosis 

      Manuel Matamala, José [Univ Mayor, Ctr Genom & Bioinformat, Fac Sci, Santiago, Chile]; Arias-Carrasco, Raúl [Univ Mayor, Ctr Genom & Bioinformat, Fac Sci, Santiago, Chile]; Sánchez, Carolina [Univ Mayor, Ctr Genom & Bioinformat, Fac Sci, Santiago, Chile]; Uhrig, Markus [Univ Mayor, Ctr Genom & Bioinformat, Fac Sci, Santiago, Chile]; Maracaja-Coutinho, Vinicius [Univ Mayor, Ctr Genom & Bioinformat, Fac Sci, Santiago, Chile]; Manque, Patricio [Univ Mayor, Ctr Genom & Bioinformat, Fac Sci, Santiago, Chile]; Bargsted, Leslie; Matus, Soledad; Abarzúa, Sebastián; van Zundert, Brigitte; Verdugo, Renato (ELSEVIER SCIENCE INC, 2018)
      The occurrence of mutations of TDP-43, FUS, and C9ORF72 in amyotrophic lateral sclerosis (ALS) suggests pathogenic alterations to RNA metabolism and specifically to microRNA (miRNA) biology. Moreover, several ALS-related ...