Listar INVESTIGACIÓN por autor "Burbulis, Ian"
Mostrando ítems 1-2 de 2
-
Cytosolic phosphoenolpyruvate carboxykinase is expressed in alpha-cells from human and murine pancreas
Gatica, Rodrigo [Univ Mayor, Escuela Vet, Fac Ciencias, Santiago, Chile]; Westermeier, Francisco; Holyoak, Todd; Martínez, Fernando; Negron, Marianne; Yanez, Alejandro J.; Nahmias, Daniel; Nualart, Francisco; Burbulis, Ian; Bertinat, Romina (WILEY, 2020)The pancreatic islets of Langerhans, mainly formed by glucagon-producing alpha-cells and insulin-producing beta-cells, are critical for glucose homeostasis. Insulin and glucagon oppositely modulate blood glucose levels in ... -
Gluconeogenic Enzymes in beta-Cells: Pharmacological Targets for Improving Insulin Secretion
Gatica, Rodrigo [Univ Mayor, Fac Ciencias, Escuela Vet]; Westermeier, Francisco; Holyoak, Todd; Asenjo, Joel L.; Nualart, Francisco; Burbulis, Ian; Bertinat, Romina (ELSEVIER SCIENCE LONDON, 2019)Pancreatic beta-cells express the gluconeogenic enzymes glucose 6-phosphatase (G6Pase), fructose 1,6-bisphosphatase (FBP), and phosphoenolpyruvate (PEP) carboxykinase (PCK), which modulate glucose-stimulated insulin secretion ...