Listar INVESTIGACIÓN por autor "Cassels, Bruce K."
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Antihyperalgesic Activity of Quillaic Acid Obtained from Quillaja saponaria Mol.
Arrau, Sylvia [Univ Mayor, Fac Med Vet, Dept Nucleo Salud]; Rodríguez-Díaz, Maite; Cassels, Bruce K.; Valenzuela-Barra, Gabriela; Delporte, Carla; Barriga, Andres; Miranda, Hugo F. (BENTHAM SCIENCE PUBL LTD, 2019)Background: Quillaja saponaria Mol. bark contains a high concentration of triterpene saponins that have been used for centuries as a cleansing, anti-inflammatory and analgesic agent in Chilean folk medicine. In earlier ... -
Boldine inhibits the alveolar bone resorption during ligature-induced periodontitis by modulating the Th17/Treg imbalance
Cafferata, Emilio A.; Castro-Saavedra, Sebastián; Fuentes-Barros, Gonzalo; Melgar-Rodriguez, Samanta; Rivera, Felipe; Carvajal, Paola; Hernández, Marcela; Cortés, Bastian, I [Centro de Biología Integrativa, Facultad de Ciencias, Universidad Mayor, Chile]; Cortez, Cristian [Centro de Genómica y Bioinformática, Facultad de Ciencias, Universidad Mayor, Chile]; Cassels, Bruce K.; Vernal, Rolando (Chile. Universidad Mayor, 2020-06)Background During periodontitis, tooth-supporting alveolar bone is resorbed when there is an increased expression of the pro-osteolytic factor termed receptor activator of nuclear factor kappa B ligand (RANKL), which is ... -
Boldo, Its Secondary Metabolites and their Derivatives
Castro-Saavedra, Sebastián [Univ Mayor, Escuela Ingn Forestal, Santiago, Chile]; Fuentes-Barros, Gonzalo [Univ Mayor, Escuela Ingn Forestal, Santiago, Chile]; Cassels, Bruce K. (BENTHAM SCIENCE PUBL LTD, 2019)Boldo leaves (Boldo folium, from Peumus boldus Mol.) are very frequently used as a medicinal herb in Chile and are exported to many countries to be used in teas or as extracts included in herbal remedies, primarily as an ... -
Variation of the alkaloid content of Peumus boldus (boldo)
Fuentes-Barros, Gonzalo [Univ Mayor, Escuela Ingn Forestal, Santiago, Chile]; Castro-Saavedra, Sebastián [Univ Mayor, Escuela Ingn Forestal, Santiago, Chile]; Liberona, Leonel; Acevedo-Fuentes, Williams; Tirapegui, Cristián; Mattar, César; Cassels, Bruce K. (ELSEVIER SCIENCE BV, 2018)Eighteen alkaloids were detected in the bark, leaves, wood and roots of Peumus boldus, including traces of secoboldine, N-methylsecoboldine (boldine methine), glaucine and norreticuline, not reported previously as constituents ...