• Clinical and pulmonary function analysis in long-COVID revealed that long-term pulmonary dysfunction is associated with vascular inflammation pathways and metabolic syndrome 

      Sanhueza, Sergio; Vidal, Mabel A.; Hernández, Mauricio A.; Henríquez-Beltrán, Mario E.; Cabrera, Camilo; Quiroga, Romina; Antilef, Bárbara E.; Aguilar, Kevin P.; Castillo, Daniela A.; Llerena, Faryd J.; Fraga Figueroa, Marco; Nazal, Mauricio; Castro, Eritson; Lagos, Paola; Moreno, Alexa; Lastra, Jaime J.; Gajardo, Jorge; Garcés, Pamela; Riffo, Benilde; Buchert, Jorge; Sanhueza, Rocío; Ormazábal, Valeska; Saldivia, Pablo; Vargas, Cristian; Nourdin, Guillermo; Koch, Elard; Zúñiga, Felipe A.; Lamperti, Liliana; Bustos, Paula; Guzmán-Gutiérrez, Enrique; Tapia, Claudio A.; Ferrada, Luciano; Cerda, Gustavo; Woehlbier, Ute [Center for Integrative Biology, Faculty of Sciences, Universidad Mayor, Chile]; Riquelme, Erick; Yuseff, María-Isabel; Muñoz Ramírez, Braulio A.; Lombardi, Giovanna; Gonzalo-Calvo, David de; Salomón, Carlos; Verdugo, Ricardo A.; Quiñones, Luis A.; Colombo, Alicia; Barría, María I.; Labarca, Gonzalo; Nova-Lamperti, Estefania (Frontiers Media S.A., 2023-10)
      Introduction: Long-term pulmonary dysfunction (L-TPD) is one of the most critical manifestations of long-COVID. This lung affection has been associated with disease severity during the acute phase and the presence of ...
    • Metformin protects from oxaliplatin induced peripheral neuropathy in rats 

      Martinez, N W [Center for Integrative Biology, Faculty of Sciences, Universidad Mayor, Chile]; Sánchez, A.; Diaz, P.; Broekhuizen, R.; Godoy, J.; Mondaca, S.; Catenaccio, A. [Center for Integrative Biology, Faculty of Sciences, Universidad Mayor, Chile]; Macanas, P.; Nervi, B.; Calvo, M.; Court, Felipe A. [Univ Mayor, Fac Sci, Ctr Integrat Biol, Chile] (Elsevier BV, 2020-08)
      Oxaliplatin is a commonly used drug to treat cancer, extending the rate of disease-free survival by 20% in colorectal cancer. However, oxaliplatin induces a disabling form of neuropathy resulting in more than 60% of patients ...
    • Senescent Schwann cells induced by aging and chronic denervation impair axonal regeneration following peripheral nerve injury 

      Geronimo-Olvera, Cristian [Center for Integrative Biology, Faculty of Sciences, Universidad Mayor, Chile]; Girardi, Karina [Center for Integrative Biology, Faculty of Sciences, Universidad Mayor, Chile]; Necuñir-Ibarra, David [Center for Integrative Biology, Faculty of Sciences, Universidad Mayor, Chile]; Kumar Patel, Sandip; Bons, Joanna; Wright, Megan C.; Geschwind, Daniel; Hoke, Ahmet; Gómez-Sánchez, José A.; Schilling, Birgit; Rebolledo, Daniela L. [Center for Integrative Biology, Faculty of Sciences, Universidad Mayor, Chile]; Campisi, Judith; Court, Felipe A. [Center for Integrative Biology, Faculty of Sciences, Universidad Mayor, Chile] (Wiley-Blackwell, 2023-12-07)
      Following peripheral nerve injury, successful axonal growth and functional recovery require Schwann cell (SC) reprogramming into a reparative phenotype, a process dependent upon c-Jun transcription factor activation. ...


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