Listar INVESTIGACIÓN por autor "Coruzzi, Gloria M."
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A balancing act: how plants integrate nitrogen and water signals
Araus, Viviana; Swift, Joseph; Alvarez, Jose M. [Centro de Genómica y Bioinformática, Facultad de Ciencias, Universidad Mayor, Chile]; Henry, Amelia; Coruzzi, Gloria M. (Oxford University Press, 2020-07-25)Nitrogen (N) and water (W) are crucial inputs for plant survival as well as costly resources for agriculture. Given their importance, the molecular mechanisms that plants rely on to signal changes in either N or W status ... -
ConnecTF: A platform to integrate transcription factor-gene interactions and validate regulatory networks
Brooks, Matthew D.; Juang, Che-Lun; Katari, Manpreet Singh; Pasquino, Angelo; Shih, Hung-Jui; Huang, Ji; Shanks, Carly; Cirrone, Jacopo; Coruzzi, Gloria M.; Alvarez, Jose M. [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Santiago, Chile] (OXFORD UNIV PRESS INC, 2021-04-28)Deciphering gene regulatory networks (GRNs) is both a promise and challenge of systems biology. The promise lies in identifying key transcription factors (TFs) that enable an organism to react to changes in its environment. ... -
Nitrate in 2020: Thirty Years from Transport to Signaling Networks
Vidal, Elena A. [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Chile]; Alvarez, Jose M. [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Chile]; Araus, Viviana; Riveras, Eleodoro; Brooks, Matthew D.; Krouk, Gabriel; Ruffel, Sandrine; Lejay, Laurence; Crawford, Nigel M.; Coruzzi, Gloria M.; Gutierrez, Rodrigo A. (American Society of Plant Biologists, 2020-07)Nitrogen (N) is an essential macronutrient for plants and a major limiting factor for plant growth and crop production. Nitrate is the main source of N available to plants in agricultural soils and in many natural environments. ... -
Nutrient dose-responsive transcriptome changes driven by Michaelis Menten kinetics underlie plant growth rates
Swift, Joseph; Alvarez, Jose M. [Centro de Genómica y Bioinformática, Facultad de Ciencias, Universidad Mayor, Chile]; Araus, Viviana; Gutiérrez, Rodrigo A.; Coruzzi, Gloria M. (National Academy of Sciences, 2020-06-09)An increase in nutrient dose leads to proportional increases in crop biomass and agricultural yield. However, the molecular underpinnings of this nutrient dose-response are largely unknown. To investigate, we assayed changes ... -
Plant ecological genomics at the limits of life in the Atacama Desert
Eshel, Gil; Araus, Viviana; Undurraga, Soledad; Soto, Daniela C.; Moraga, Carol; Montecinos, Alejandro; Moyano, Tomas C.; Maldonado, Jonathan; Díaz, Francisca P.; Varala, Kranthi; Nelson, Chase W.; Contreras-López, Orlando; Pal-Gabor, Henrietta; Kraiser, Tatiana; Carrasco-Puga, Gabriela; Nilo-Poyanco, Ricardo [Univ Mayor, Fac Ciencias, Escuela Biotecnol, Chile]; Zegar, Charles M.; Orellana, Ariel; Montecino, Martin; Maass, Alejandro; Allende, Miguel L.; DeSalle, Robert; Stevenson, Dennis W.; González, Mauricio; Latorre, Claudio; Coruzzi, Gloria M.; Gutiérrez, Rodrigo A. (NATL ACAD SCIENCES, 2021-11-16)The Atacama Desert in Chile-hyperarid and with high-ultraviolet irradiance levels-is one of the harshest environments on Earth. Yet, dozens of species grow there, including Atacama-endemic plants. Herein, we establish the ... -
Time-Based Systems Biology Approaches to Capture and Model Dynamic Gene Regulatory Networks
Alvarez, Jose M.; Brooks, Matthew D.; Swift, Joseph; Coruzzi, Gloria M.; Alhafez, Iyad Alabd [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Chile] (ANNUAL REVIEWS, 2021-07-19)All aspects of transcription and its regulation involve dynamic events. However, capturing these dynamic events in gene regulatory networks (GRNs) offers both a promise and a challenge. The promise is that capturing and ... -
Transient genome-wide interactions of the master transcription factor NLP7 initiate a rapid nitrogen-response cascade
Alvarez, Jose M. [Centro de Genómica y Bioinformática, Facultad de Ciencias, Universidad Mayor, Chile]; Schinke, Anna-Lena; Brooks, Matthew D.; Pasquino, Angelo; Leonelli, Lauriebeth; Varala, Kranthi; Safi, Alaeddine; Krouk, Gabriel; Krapp, Anne; Coruzzi, Gloria M. (Nature Publishing Group, 2020-03-02)Dynamic reprogramming of gene regulatory networks (GRNs) enables organisms to rapidly respond to environmental perturbation. However, the underlying transient interactions between transcription factors (TFs) and genome-wide ...