Listar INVESTIGACIÓN por autor "Court, Felipe A. [Univ Mayor, Fac Sci, Ctr Integrat Biol, Santiago, Chile]"
Mostrando ítems 1-3 de 3
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Altered mitochondrial bioenergetics are responsible for the delay in Wallerian degeneration observed in neonatal mice
Court, Felipe A. [Univ Mayor, Fac Sci, Ctr Integrat Biol, Santiago, Chile]; Martínez, Nicolás W. [Univ Mayor, Fac Sci, Ctr Integrat Biol, Santiago, Chile]; Kline, Rachel A.; Dissanayake, Kosala N.; Hurtado, Maica Llavero; Ahl, Alexander; Mole, Alannah J.; Lamont, Douglas J.; Ribchester, Richard R.; Wishart, Thomas M.; Murray, Lyndsay M. (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2019)Neurodegenerative and neuromuscular disorders can manifest throughout the lifespan of an individual, from infant to elderly individuals. Axonal and synaptic degeneration are early and critical elements of nearly all human ... -
Necroptosis Inhibition Counteracts Neurodegeneration, Memory Decline, And Key Hallmarks Of Aging, Promoting Brain Rejuvenation
Arrazola, Macarena S; Lira, Matias; Quiroz, Gabriel; Iqbal, Somya; Eaton, Samantha L.; Lamont, Douglas J.; Ureta, Gonzalo; Bernales, Sebastian; Cerpa, Waldo; Wishart, Thomas M.; Véliz-Valverde, Felipe [Univ Mayor, Fac Sci, Ctr Integrat Biol, Santiago, Chile]; Huerta, Hernán [Univ Mayor, Fac Sci, Ctr Integrat Biol, Santiago, Chile]; Cardenas, J. Cesar [Univ Mayor, Fac Sci, Ctr Integrat Biol, Santiago, Chile]; Court, Felipe A. [Univ Mayor, Fac Sci, Ctr Integrat Biol, Santiago, Chile] (2023) -
Non-canonical function of IRE1 alpha determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics
César Cardenas, J. [Univ Mayor, Fac Sci, Ctr Integrat Biol, Santiago, Chile]; Court, Felipe A. [Univ Mayor, Fac Sci, Ctr Integrat Biol, Santiago, Chile]; Luke Wiseman, R. [Univ Mayor, Fac Sci, Ctr Integrat Biol, Santiago, Chile]; Bustos, Galdo [Univ Mayor, Fac Sci, Ctr Integrat Biol, Santiago, Chile]; Carreras-Sureda, Amado; Jana, Fabian; Urra, Hery; Duránd, Sylvere; Mortenson, David E.; Sagredo, Alfredo; Hazari, Younis; Ramos-Fernández, Eva; Sassano, María L.; Pihan, Philippe; van Vliet, Alexander R.; González-Quiroz, Matias; Torres, Angie K.; Tapia-Rojas, Cheril; Kerkhofs, Martijn; Vicente, Ruben; Kaufman, Randal J.; Inestrosa, Nibaldo C.; González-Billault, Christian; Agostinis, Patrizia; Bultynck, Geert; Kroemer, Guido; Hetz, Claudio (NATURE PUBLISHING GROUP, 2019)Mitochondria-associated membranes (MAMs) are central microdomains that fine-tune bioenergetics by the local transfer of calcium from the endoplasmic reticulum to the mitochondrial matrix. Here, we report an unexpected ...