Listar INVESTIGACIÓN por autor "Ferrada, Evandro [Univ Mayor, Fac Sci, Ctr Genom & Bioinformat]"
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Gene Families, Epistasis and the Amino Acid Preferences of Protein Homologs
Ferrada, Evandro [Univ Mayor, Fac Sci, Ctr Genom & Bioinformat] (SAGE PUBLICATIONS LTD, 2019)In order to preserve structure and function, proteins tend to preferentially conserve amino acids at particular sites along the sequence. Because mutations can affect structure and function, the question arises whether the ... -
The Site-Specific Amino Acid Preferences of Homologous Proteins Depend on Sequence Divergence
Ferrada, Evandro [Univ Mayor, Fac Sci, Ctr Genom & Bioinformat] (OXFORD UNIV PRESS, 2019)The propensity of protein sites to be occupied by any of the 20 amino acids is known as site-specific amino acid preferences (SSAP). Under the assumption that SSAP are conserved among homologs, they can be used to parameterize ...