Listar INVESTIGACIÓN por autor "Guzmán, Eghon [Univ Mayor, Fac Med, Chile]"
Mostrando ítems 1-5 de 5
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Minimal Residual Disease Defines the Risk and Time to Biochemical Failure in Patients with Pt2 and Pt3a Prostate Cancer Treated With Radical Prostatectomy: An Observational Prospective Study
Murray, Nigel P.; Aedo, Socrates; Fuentealba, Cynthia; Reyes, Eduardo; Salazar, Anibal; Minzer, Simona; López, Marco Antonio [Univ Mayor, Fac Med, Chile]; Orrego, Shenda [Univ Mayor, Fac Med, Chile]; Guzmán, Eghon [Univ Mayor, Fac Med, Chile] (Chile. Universidad Mayor, 2020)Purpose: To compare Gleason score (GS), pathological stage, minimal residual disease (MRD) and outcome after prostatectomy radical for prostate cancer. Patients and Methods: 290/357 men with GS 6 or 7 and pT2 or pT3a disease ... -
Subtypes of minimal residual disease and outcome for stage II colon cancer treated by surgery alone
Murray, Nigel P.; Aedo, Socrates; Villalón, Ricardo; Albarran, Vidal; Orrego, Shenda [Univ Mayor, Fac Med, Chile]; Guzmán, Eghon [Univ Mayor, Fac Med, Chile] (Cancer Intellilgence, 2020-10)Introduction: Twenty-five percent of stage II colon cancer (CC) patients relapse within 5 years due to minimal residual disease (MRD) not eliminated by surgery. We hypothesise that subtypes of MRD, defined by circulating ... -
The association of the neutrophil-lymphocyte ratio with the presence of minimal residual disease and outcome in patients with Stage II colon cancer treated with surgery alone
Murray, Nigel P.; Villalón, Ricardo; Orrego, Shenda [Univ Mayor, Fac Med, Chile]; Guzmán, Eghon [Univ Mayor, Fac Med, Chile] (Wiley-Blackwell Publishing Ltd, 2021-04)Aim Despite curative surgery, 25% of patients with Stage II colorectal cancer will relapse due to minimal residual disease (MRD). Markers of immune function, such as the neutrophil to lymphocyte ratio (NLR), may be associated ... -
The CAPRA-S score versus subtypes of minimal residual disease to predict biochemical failure after radical prostatectomy
Murray, Nigel P.; Aedo, Socrates; Fuentealba, Cynthia; Reyes, Eduardo; Salazar, Anibal; Orrego, Shenda [Univ Mayor, Fac Med, Chile]; Guzmán, Eghon [Univ Mayor, Fac Med, Chile] (Cancer Intellilgence, 2020-06)Objective: The objective of this study was to compare the CAPRA-S score (based on clinicopathological findings) and the subtypes of minimal residual disease (MRD) (based on the biological properties of cancer cells) to ... -
The expression of matrix-metalloproteinase-2 in bone marrow micro-metastasis is associated with the presence of circulating prostate cells and a worse prognosis in men treated with radical prostatectomy for prostate cancer
Murray, Nigel P.; Reyes, Eduardo; Salazar, Anibal; López, Marco Antonio [Univ Mayor, Fac Med, Santiago, Chile]; Orrego, Shenda [Univ Mayor, Fac Med, Chile]; Guzmán, Eghon [Univ Mayor, Fac Med, Chile] (Aves, 2020-05)Objective: The expression of matrix-metalloproteinase-2 (MMP-2) in the primary tumor is associated with a worse prognosis but little is known at this time regarding the expression in micro-metastasis, the association with ...