Listar INVESTIGACIÓN por autor "Hetz, Claudio [Universidad de Chile]"
Mostrando ítems 1-3 de 3
-
Commentary: XBP-1 Is a Cell-Nonautonomous Regulator of Stress Resistance and Longevity
Duran-Aniotz, Claudia [Universidad de Chile]; Cabral-Miranda, Felipe [Universidad de Chile]; Hetz, Claudio [Universidad de Chile] (CIENCIAS, 2016)The life expectancy in the world's population is increasing, highlighting the need of better understanding of the cellular and molecular pathways that drive the aging process. Because aging is the major risk factor to ... -
Identification of rare protein disulfide isomerase gene variants in amyotrophic lateral sclerosis patients.
Gonzalez-Perez, Paloma [University of Massachusetts]; Woehlbier, Ute [Chile. Universidad Mayor]; Chian, Ru-Ju [Universidad de Chile]; Sapp, Peter [University of Massachusetts]; Rouleau, Guy A. [Montreal Neurological Institute and Hospital]; Leblond, Claire S. [Montreal Neurological Institute and Hospital]; Daoud, Hussein [Montreal Neurological Institute and Hospital]; Dion, Patrick A. [Montreal Neurological Institute and Hospital]; Landers, John E. [University of Massachusetts]; Hetz, Claudio [Universidad de Chile]; Brown, Robert H. [Universidad de Chile] (Facultad de Ciencias, 2015)Disruption of endoplasmic reticulum (ER) proteostasis is a salient feature of amyotrophic lateral sclerosis (ALS). Upregulation of ER foldases of the protein disulfide isomerase (PDI) family has been reported in ALS mouse ... -
Injury to the nervous system: A look into the ER
Oñate, Maritza [Chile. Universidad Mayor]; Hetz, Claudio [Universidad de Chile]; Court, Felipe A [Chile. Universidad Mayor] (CIENCIAS, 2016)Injury to the central or peripheral nervous systems leads to the loss of cognitive and/or sensorimotor capabilities that still lack an effective treatment. Although injury to the nervous system involves multiple and complex ...