Listar INVESTIGACIÓN por autor "Lagos, Carolina"
Mostrando ítems 1-4 de 4
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Aberrant MUC1 accumulation in salivary glands of Sjogren's syndrome patients is reversed by TUDCA in vitro
Castro, Isabel; Albornoz, Nicolás; Aguilera, Sergio; Barrera, María-José; González, Sergio [Universidad Mayor, Chile]; Nuñez, Matilde; Carvajal, Patricia; Jara, Daniela; Lagos, Carolina; Molina, Claudio; Urzua, Ulises; Hermoso, Marcela A.; González, María-Julieta (Oxford University Press, 2020-04)Objectives. Xerostomia in SS patients has been associated with low quality and quantity of salivary mucins, which are fundamental for the hydration and protection of the oral mucosa. The aim of this study was to evaluate ... -
Association of high 5-hydroxymethylcytosine levels with Ten Eleven Translocation 2 overexpression and inflammation in Sjogren's syndrome patients
González, Sergio [Univ Mayor, Fac Ciencias, Escuela Odontol, Santiago, Chile]; Lagos, Carolina; Caryajal, Patricia; Castro, Isabel; Jara, Daniela; Aguilera, Sergio; Barrera, María-José; Quest, Andrew F. G.; Bahamondes, Veronica; Molina, Claudio; Urzua, Ulises; Hermoso, Marcela A.; Leyton, Cecilia; González, María-Julieta (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2018)Here, we determined the 5-hydroxymethylcytosine (5hmC), 5-methylcytosine (5mC), Ten Eleven Translocation (TETs), and DNA methyltransferases (DNMTs) levels in epithelial and inflammatory cells of labial salivary glands (LSG) ... -
Impaired IRE1 alpha/XBP-1 pathway associated to DNA methylation might contribute to salivary gland dysfunction in Sjogren's syndrome patients
González, Sergio [Univ Mayor, Fac Ciencias, Escuela Odontol, Santiago, Chile]; Molina, Claudio [Univ Mayor, Fac Ciencias, Dept Patol Oral, Escuela Odontol, Santiago, Chile]; Sepúlveda, Denisse; Barrera, María-José; Castro, Isabel; Aguilera, Sergio; Carvajal, Patricia; Lagos, Carolina; Albornoz, Nicolás; Bahamondes, Verónica; Quest, Andrew F. G.; Urzua, Ulises; Leyton, Cecilia; Hermoso, Marcela A.; González, María-Julieta (OXFORD UNIV PRESS, 2018)Objectives. Labial salivary glands (LSGs) of SS patients show alterations related to endoplasmic reticulum stress. Glandular dysfunction could be partly the consequence of an altered inositol-requiring enzyme 1 alpha (IRE1 ... -
Promoter dna methylation and HSA-MIR-424-5P regulate ATF6 alpha expression in salivary glands of patients with Sjogren's syndrome
González, Sergio [Univ Mayor, Escuela Odontol, Santiago, Chile]; Carvajal, Patricia; Aguilera, Sergio; Barrera, Maria-Jose; Lagos, Carolina; Castro, Isabel; Jara, Daniela; Molina, Claudio; González, Maria-Julieta (BMJ PUBLISHING GROUP, 2019)Sin resumen