Listar INVESTIGACIÓN por autor "Massieu, Lourdes"
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Autophagy as a Homeostatic Mechanism in Response to Stress Conditions in the Central Nervous System
Geronimo-Olvera, Cristián [Univ Mayor, Fac Sci, Ctr Integrat Biol, Santiago, Chile]; Massieu, Lourdes (SPRINGER, 2019)Autophagy is considered a major bulk degradation system that helps cells to counteract different intracellular and extracellular stress signals. Several protein complexes integrate multiple signals in order to activate ... -
IRE1α RIDD activity induced under ER stress drives neuronal death by the degradation of 14-3-3 θ mRNA in cortical neurons during glucose deprivation
Gómora-García, Juan Carlos; Gerónimo-Olvera, Cristian [Univ Mayor, Fac Sci, Ctr Integrat Biol, Chile]; Pérez-Martínez, Xochitl; Massieu, Lourdes (SPRINGER NATURE, 2021-06-03)Altered protein homeostasis is associated with neurodegenerative diseases and acute brain injury induced under energy depletion conditions such as ischemia. The accumulation of damaged or unfolded proteins triggers the ...