Listar INVESTIGACIÓN por autor "Murray, Nigel P."
Mostrando ítems 1-10 de 10
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Common B-cell acute lymphoblastic leukaemia in a 70-year-old woman presenting 2 years after carboplatin-taxane radiotherapy for endometrial cancer
Múñoz, Lorena [Univ Mayor, Fac Med]; Antonio López, Marco [Univ Mayor, Fac Med]; Orrego, Shenda [Univ Mayor, Fac Med]; Murray, Nigel P.; Minzer, Simona (CANCER INTELLIGENCE LTD, 2019)Therapy-related acute lymphoblastic leukaemia (t-ALL) is a poorly defined entity and is not featured in the World Health Organization classification as a distinct clinical entity from acute lymphoblastic leukaemia (ALL), ... -
Effect of FOLFOX on minimal residual disease in Stage III colon cancer and risk of relapse
Guzmán, Eghon [Univ Mayor, Fac Med]; Arzeno, Lucas [Univ Mayor, Fac Med]; Aedo, Socrates; Villalon, Ricardo; Murray, Nigel P. (CANCER INTELLIGENCE LTD, 2019)Introduction: 25% of Stage III colon cancer patients relapse within 5 years due to minimal residual disease (MRD) not eliminated by surgery and chemotherapy. We hypothesise that sub-types of MRD, defined by circulating ... -
Management of Thrombosis Risk in a Carrier of Hemophilia A with Low Factor VIII Levels with Atrial Fibrillation: A Clinical Case and Literature Review
Muñoz, Lorena [Univ Mayor, Fac Med, Med, Camino La Piramide 5750, Huechuraba 8580745, Santiago De, Chile]; Murray, Nigel P.; Minzer, Simona; Antonio López, Marco (HINDAWI LTD, 2018)Nonvalvular atrial fibrillation (AF) is a common age-related arrthymia and a leading cause of stroke in the elderly; with an aging hemophilia population, the number of patients developing AF is increasing. There are no ... -
Minimal Residual Disease Defines the Risk and Time to Biochemical Failure in Patients with Pt2 and Pt3a Prostate Cancer Treated With Radical Prostatectomy: An Observational Prospective Study
Murray, Nigel P.; Aedo, Socrates; Fuentealba, Cynthia; Reyes, Eduardo; Salazar, Anibal; Minzer, Simona; López, Marco Antonio [Univ Mayor, Fac Med, Chile]; Orrego, Shenda [Univ Mayor, Fac Med, Chile]; Guzmán, Eghon [Univ Mayor, Fac Med, Chile] (Chile. Universidad Mayor, 2020)Purpose: To compare Gleason score (GS), pathological stage, minimal residual disease (MRD) and outcome after prostatectomy radical for prostate cancer. Patients and Methods: 290/357 men with GS 6 or 7 and pT2 or pT3a disease ... -
Predictive Value of Neutrophil to Lymphocyte Ratio in the Diagnosis of Significant Prostate Cancer at Initial Biopsy: A Comparison with Free Percent Prostate Specific Antigen, Prostate Specific Antigen Density and Primary Circulating Prostate Cells
Murray, Nigel P.; Fuentealba, Cynthia; Reyes, Eduardo; López, Marco Antonio; Salazar, Anibal; Minzer, Simona; Muñoz, Lorena; Orrego, Shenda; Guzman, Eghon [Chile. Universidad Mayor] (Chile. Universidad Mayor, 2019)Introduction: An elevated serum PSA is the only biomarker routinely used in screening for prostate cancer to indicate a prostate biopsy. However, it is not specific for prostate cancer and the neutrophil/lymphocyte ratio ... -
Subtypes of minimal residual disease and outcome for stage II colon cancer treated by surgery alone
Murray, Nigel P.; Aedo, Socrates; Villalón, Ricardo; Albarran, Vidal; Orrego, Shenda [Univ Mayor, Fac Med, Chile]; Guzmán, Eghon [Univ Mayor, Fac Med, Chile] (Cancer Intellilgence, 2020-10)Introduction: Twenty-five percent of stage II colon cancer (CC) patients relapse within 5 years due to minimal residual disease (MRD) not eliminated by surgery. We hypothesise that subtypes of MRD, defined by circulating ... -
Subtypes of minimal residual disease, association with Gleason score, risk and time to biochemical failure in pT2 prostate cancer treated with radical prostatectomy
Guzmán, Eghon [Univ Mayor, Fac Med]; Orrego, Shenda [Univ Mayor, Fac Med]; Aedo, Socrates; Fuentealba, Cynthia; Reyes, Eduardo; Salazar, Anibal; Murray, Nigel P. (CANCER INTELLIGENCE LTD, 2019)Introduction: The Gleason score is a strong prognostic factor for treatment failure in pathologically organ-confined prostate cancer (pT2) treated by radical prostatectomy (RP). However, within each Gleason score, there ... -
The association of the neutrophil-lymphocyte ratio with the presence of minimal residual disease and outcome in patients with Stage II colon cancer treated with surgery alone
Murray, Nigel P.; Villalón, Ricardo; Orrego, Shenda [Univ Mayor, Fac Med, Chile]; Guzmán, Eghon [Univ Mayor, Fac Med, Chile] (Wiley-Blackwell Publishing Ltd, 2021-04)Aim Despite curative surgery, 25% of patients with Stage II colorectal cancer will relapse due to minimal residual disease (MRD). Markers of immune function, such as the neutrophil to lymphocyte ratio (NLR), may be associated ... -
The CAPRA-S score versus subtypes of minimal residual disease to predict biochemical failure after radical prostatectomy
Murray, Nigel P.; Aedo, Socrates; Fuentealba, Cynthia; Reyes, Eduardo; Salazar, Anibal; Orrego, Shenda [Univ Mayor, Fac Med, Chile]; Guzmán, Eghon [Univ Mayor, Fac Med, Chile] (Cancer Intellilgence, 2020-06)Objective: The objective of this study was to compare the CAPRA-S score (based on clinicopathological findings) and the subtypes of minimal residual disease (MRD) (based on the biological properties of cancer cells) to ... -
The expression of matrix-metalloproteinase-2 in bone marrow micro-metastasis is associated with the presence of circulating prostate cells and a worse prognosis in men treated with radical prostatectomy for prostate cancer
Murray, Nigel P.; Reyes, Eduardo; Salazar, Anibal; López, Marco Antonio [Univ Mayor, Fac Med, Santiago, Chile]; Orrego, Shenda [Univ Mayor, Fac Med, Chile]; Guzmán, Eghon [Univ Mayor, Fac Med, Chile] (Aves, 2020-05)Objective: The expression of matrix-metalloproteinase-2 (MMP-2) in the primary tumor is associated with a worse prognosis but little is known at this time regarding the expression in micro-metastasis, the association with ...