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    • Identification of Thiotetronic Acid Antibiotic Biosynthetic Pathways by Target-directed Genome Mining 

      Tang, Xiaoyu [Estados Unidos. University of California. Institution of Oceanography]; Li, Jie [Estados Unidos. University of California San Diego. Scripps Institution of Oceanography]; Millan-Aguinaga, Natalie [Estados Unidos. University of California San Diego. Scripps Institution of Oceanography]; Zhang, Jia Jia [Estados Unidos. University of California San Diego. Scripps Institution of Oceanography]; O'Neill, Ellis C. [Estados Unidos. University of California. Scripps Institution of Oceanography]; Ugalde, Juan A [Chile. Universidad Mayor Facultad de Ciencias]; Jensen, Paul R [Estados Unidos. University of California San Diego. Scripps Institution of Oceanography]; Mantovani, Simone M. [Estados Unidos. University of California. Scripps Institution of Oceanography]; Moore, Bradley S. [Estados Unidos. University of California San Diego. Scripps Institution of Oceanography] (CIENCIAS, 2015)
      Recent genome sequencing efforts have led to the rapid accumulation of uncharacterized or "orphaned" secondary metabolic biosynthesis gene clusters (BGCs) in public databases. This increase in DNA-sequenced big data has ...