• Genome sequencing reveals molecular subgroups in oral epithelial dysplasia 

      Márquez, Agustín; Mujica, Isidora; Jordán, Natalia; Báez, Pablo; Tarquinio, Sandra; Nunes, Jean; Adorno, Daniela; Martínez, Benjamín [Univ Mayor, Fac Dent, Santiago, Chile]; Morales-Pisón, Sebastián [Univ Mayor, Precis Oncol Ctr, Santiago, Chile]; Fernández-Remires, Ricardo [Univ Mayor, Fac Med & Heatlh Sci, Santiago, Chile] (SOCIEDADE BRASILEIRA DE PESQUISA ODONTOLOGICA, 2023-07-16)
      This study aimed to analyze the molecular characteristics of oral epithelial dysplasia (OED), highlighting the pathways and variants of genes that are frequently mutated in oral squamous cell carcinoma (OSCC) and other ...
    • Whole-exome sequencing of oral epithelial dysplasia samples reveals an association with new genes 

      Adorno-Farias, Daniela; Nunes dos Santos, Jean; González-Arriagada, Wilfredo; Tarquinio, Sandra; Santibáñez Palominos, Rodrigo Alberto [Univ Mayor UMAYOR, Ctr Genom & Bioinformat, Sch Sci, Network Biol Lab, Santiago, Chile]; Martin Martin, Alberto Jesús; Fernández-Ramires, Ricardo (SOCIEDADE BRASILEIRA DE PESQUISA ODONTOLOGICA, 2023-03-23)
      The genetic basis of oral epithelial (OED) is unknown, and there is no reliable method for evaluating the risk of malignant transformation. Somatic mutations are responsible for the transformation of dysplastic mucosa to ...


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