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Elimination of primary circulating prostate cells after radical prostatectomy for prostate cancer decreases the risk of future biochemical failure
(Facultad de Ciencias, 2014)
OBJECTIVES: Primary CPCs are those detected in the blood of prostate cancer patients before radical treatment; secondary CPCs are those detected afterwards. Although primary CPCs are frequently found, it has been suggested ...
Head-to-head comparison of the Montreal nomogram with the detection of primary malignant circulating prostate cells to predict prostate cancer at initial biopsy in Chilean men with suspicion of prostate cancer
(Facultad de Ciencias, 2015)
INTRODUCTION: The limitations of total serum prostate-specific antigen (PSA) level values remain problematic. Nomograms may improve the predictive value of a positive prostate biopsy (PB) finding. We compare in a prospective ...
Circulating prostate cells found in men with benign prostate disease are P504S negative: Clinical implications
(Facultad de Ciencias, 2013)
Introduction. Developments in immunological and quantitative real-time PCR-based analysis have enabled the detection, enumeration, and characterization of circulating tumor cells (CTCs). It is assumed that the detection ...
Prostate cancer screening in the fit chilean elderly: A head to head comparison of total serum PSA versus age adjusted PSA versus primary circulating prostate cells to detect prostate cancer at initial biopsy
(Facultad de Ciencias, 2015)
BACKGROUND: Prostate cancer is predominately a disease of older men, with a median age of diagnosis of 68 years and 71% of cancer deaths occurring in those over 75 years of age. While prostate cancer screening is not ...
Primary circulating prostate cells are not detected in men with low grade small volume prostate cancer
(Facultad de Ciencias, 2014)
Objective. To determine if primary circulating prostate cells (CPCs) are found in all men with prostate cancer. Methods and Patients. A prospective study, to analyze all men with an elevated PSA between 4.0 and 10.0 ng/mL ...
Effect of androgen blockade on her-2 and matrix metalloproteinase-2 expression on bone marrow micrometastasis and stromal cells in men with prostate cancer
(Facultad de Ciencias, 2013)
INTRODUCTION: HER-2 has been associated with castrate resistant prostate cancer and matrix metalloproteinase-2 (MMP-2) in the dissemination and invasion of tumor cells as well as activating angiogenesis. We present an ...
Rendimiento diagnóstico de la detección de células prostáticas malignas en la circulación sanguínea para la detección precoz de cáncer prostático: Una comparación con la biopsia prostática
(Facultad de Ciencias, 2011)
OBJECTIVES: Serum prostate specific antigen and digital rectal examination are the tests used as screening tests to detect prostate cancer. However, only approximately 30% of men with suspicion of cancer have it confirmed ...