Mostrando ítems 3121-3140 de 7669

    • Whole Genome Sequence, Variant Discovery and Annotation in Mapuche-Huilliche Native South Americans 

      Vizoso, Paula [Univ Mayor, Fac Ciencias, Ctr Propagac Conservac Vegetal CEPROVEG, Santiago, Chile]; Vidal, Elena A. [Univ Mayor, Fac Ciencias, Ctr Geneim Bioinformat, Santiago, Chile]; Moyano, Tomás C.; Bustos, Bernabe, I; Pérez-Palma, Eduardo; Moraga, Carol; Riveras, Eleodoro; Montecinos, Alejandro; Azocar, Lorena; Soto, Daniela C.; Vidal, Mabel; Di Genoval, Alex; Puschel, Klaus; Nurnberg, Peter; Buch, Stephan; Hampe, Jochen; Allende, Miguel L.; Cambiazo, Veronica; González, Mauricio; Hodar, Christian; Montecino, Martin; Muñoz-Espinoza, Claudia; Orellana, Ariel; Reyes-Jara, Angelica; Travisanyl, Dante; Moraga, Mauricio; Eyheramendy, Susana; Maass, Alejandro; De Ferrari, Giancarlo, V; Mique, Juan Francisco; Gutiérrez, Rodrigo A. (NATURE PUBLISHING GROUP, 2019)
      Whole human genome sequencing initiatives help us understand population history and the basis of genetic diseases. Current data mostly focuses on Old World populations, and the information of the genomic structure of Native ...
    • Intermediate-Salinity Systems at High Altitudes in the Peruvian Andes Unveil a High Diversity and Abundance of Bacteria and Viruses 

      Pérez-Rueda, Ernesto [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat]; Gildardo Castelan-Sánchez, Hugo; Elorrieta, Paola; Romoacca, Pedro; Linan-Torres, Arturo; Luis Sierra, Jose; Vera, Ingrid; Alberto Batista-Garcia, Ramon; Tenorio-Salgado, Silvia; Lizama-Uc, Gabriel; Antonieta Quispe-Ricalde, Maria; Davila-Ramos, Sonia (MDPI, 2019)
      Intermediate-salinity environments are distributed around the world. Here, we present a snapshot characterization of two Peruvian thalassohaline environments at high altitude, Maras and Acos, which provide an excellent ...
    • Tracing the phylogenetic history of the Crl regulon through the Bacteria and Archaea genomes 

      Pérez-Rueda, E. [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Santiago, Chile]; Santos-Zavaleta, A.; Sánchez-Pérez, M.; Velazquez-Ramírez, D. A.; Collado-Vides, J. (BMC, 2019)
      Background: Crl, identified for curli production, is a small transcription factor that stimulates the association of the sigma(S) factor (RpoS) with the RNA polymerase core through direct and specific interactions, increasing ...
    • Effect of CO2 Concentration on Uptake and Assimilation of Inorganic Carbon in the Extreme Acidophile Acidithiobacillus ferrooxidans 

      Holmes, David S.[Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Santiago, Chile]; Esparza, Mario; Jedlicki, Eugenia; González, Carolina; Dopson, Mark (FRONTIERS MEDIA SA, 2019)
      This study was motivated by surprising gaps in the current knowledge of microbial inorganic carbon (Ci) uptake and assimilation at acidic pH values (pH < 3). Particularly striking is the limited understanding of the ...
    • ATP6V(0)d2 controls Leishmania parasitophorous vacuole biogenesis via cholesterol homeostasis 

      Cortez, Cristián [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Santiago, Chile]; Pessoa, Carina Carraro; Reis, Luiza Campos; Ramos-Sánchez, Eduardo Milton; Orikaza, Cristina Mary; de Castro Levatti, Erica Valadares; Benites Badaro, Ana Carolina; da Silva Yamamoto, Joyce Umbelino; D'Almeida, Vania; Goto, Hiro; Mortara, Renato Arruda; Real, Fernando (PUBLIC LIBRARY SCIENCE, 2019)
      V-ATPases are part of the membrane components of pathogen-containing vacuoles, although their function in intracellular infection remains elusive. In addition to organelle acidification, V-ATPases are alternatively implicated ...
    • Non-lysosomal Activation in Macrophages of Atlantic Salmon (Salmo salar) After Infection With Piscirickettsia salmonis 

      Reyes-Cerpa, Sebastián [Univ Mayor, Ctr Genom & Bioinformat, Fac Ciencias, Santiago, Chile]; Valdés, Jorge [Univ Mayor, Ctr Genom & Bioinformat, Fac Ciencias, Santiago, Chile]; Ibaceta, Valentina [Univ Mayor, Ctr Genom & Bioinformat, Fac Ciencias, Santiago, Chile]; Brianson, Bernardo [Univ Mayor, Ctr Genom & Bioinformat, Fac Ciencias, Santiago, Chile]; Espinoza, Allison [Univ Mayor, Ctr Genom & Bioinformat, Fac Ciencias, Santiago, Chile]; Ahumada, Diego E. [Univ Mayor, Ctr Genom & Bioinformat, Fac Ciencias, Santiago, Chile]; Tapia, Sebastián [Univ Mayor, Ctr Genom & Bioinformat, Fac Ciencias, Santiago, Chile]; Pérez-Stuardo, Diego [Univ Mayor, Ctr Genom & Bioinformat, Fac Ciencias, Santiago, Chile]; Morales-Reyes, Jonathan; Espinoza, Allison; Soto-Herrera, Valentina; Sandino, Ana M.; Spencer, Eugenio; Vallejos-Vidal, Eva; Reyes-López, Felipe E. (FRONTIERS MEDIA SA, 2019)
      Piscirickettsia salmonis is a facultative intracellular pathogen and etiological agent of the systemic disease salmonid rickettsial septicemia. It has been suggested that P salmonis is able to survive in host macrophages, ...
    • Uncovering the Mechanisms of Halotolerance in the Extremely Acidophilic Members of the Acidihalobacter Genus Through Comparative Genome Analysis 

      Holmes, David S. [Univ Mayor, Sci Life Fdn, Ctr Bioinformat & Genome Biol, Santiago, Chile]; González, Carolina [Univ Mayor, Sci Life Fdn, Ctr Bioinformat & Genome Biol, Santiago, Chile]; Khaleque, Himel N.; Shafique, Raihan; Kaksonen, Anna H.; Watkin, Elizabeth L. J. (FRONTIERS MEDIA SA, 2019)
      There are few naturally occurring environments where both acid and salinity stress exist together, consequently, there has been little evolutionary pressure for microorganisms to develop systems that enable them to deal ...
    • Identification of functional signatures in the metabolism of the three cellular domains of life 

      Pérez-Rueda, Ernesto {Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Santiago, Chile]; Escobar-Turriza, Pedro; Hernández-Guerrero, Rafael; César Poot-Hernández, Augusto; Rodríguez-Vazquez, Katya; Ramírez-Prado, Jorge (PUBLIC LIBRARY SCIENCE, 2019)
      In order to identify common and specific enzymatic activities associated with the metabolism of the three cellular domains of life, the conservation and variations between the enzyme contents of Bacteria, Archaea, and ...
    • Signal peptide recognition in Trypanosoma cruzi GP82 adhesin relies on its localization at protein N-terminus 

      Cortez, Cristián [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Santiago, Chile]; Cordero, Esteban M. [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Santiago, Chile]; Yoshida, Nobuko; da Silveira, JoséFranco (NATURE PUBLISHING GROUP, 2019)
      Trypanosoma cruzi, the causative agent of Chagas disease, has a dense coat of GPI-anchored virulence factors. T. cruzi GPI-anchored adhesin GP82 is encoded by a repertoire of transcripts containing several in-frame initiation ...
    • Identification and Unusual Properties of the Master Regulator FNR in the Extreme Acidophile Acidithiobacillus ferrooxidans 

      Holmes, David S. [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Santiago, Chile]; Osorio, Hector; Mettert, Erin; Kiley, Patricia; Dopson, Mark; Jedlicki, Eugenia (FRONTIERS MEDIA SA, 2019)
      The ability to conserve energy in the presence or absence of oxygen provides a metabolic versatility that confers an advantage in natural ecosystems. The switch between alternative electron transport systems is controlled ...
    • NOTCH3 Gene Mutation in a Chilean Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy Family 

      Sánchez, Carolina [Univ Mayor, Ctr Genom & Bioinformat, Santiago, Chile]; Fonseca, Beatriz [Univ Mayor, Ctr Genom & Bioinformat, Santiago, Chile]; Rivera, Alejandra [Univ Mayor, Ctr Genom & Bioinformat, Santiago, Chile]; Latapiat, Verónica [Univ Mayor, Ctr Genom & Bioinformat, Santiago, Chile]; Gallardo, Andres; Roldan, Andres; Sandoval, Patricio; Manuel Matamala, Jose (ELSEVIER, 2020)
      Introduction: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a rare hereditary stroke disorder caused by mutations in the NOTCH3 gene. We report the first Chilean ...
    • Evaluation of the Abundance of DNA-Binding Transcription Factors in Prokaryotes 

      Pérez-Rueda, Ernesto [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat]; Sánchez, Israel; Hernández-Guerrero, Rafael; Méndez-Monroy, Paul Erick; Martínez-Nunez, Mario Alberto; Ibarra, JoséAntonio (MDPI, 2020)
      The ability of bacteria and archaea to modulate metabolic process, defensive response, and pathogenic capabilities depend on their repertoire of genes and capacity to regulate the expression of them. Transcription factors ...
    • Relationship between photo-physical and electrochemical properties of D--A compounds regarding solar cell applications. 1. Substituent type effect in photovoltaic performance 

      Ramírez, A. M. R. [Univ Mayor, Fac Estudios Interdisciplinarios, Lab Electroquim, Nucleo Quim & Bioquim, Temuco, Chile]; Ortega, E.; Christian Bernede, Jean; Louarn, G.; Díaz, F. R.; Cattin, L.; Angelica del Valle, Maria (SPRINGER, 2019)
      Studying the electrochemical characteristics is an important step for determining interactions between molecules and the chemical environment. Moreover, the electrochemical evaluation of dyes is highly needed to establish ...
    • Physical-chemical properties of M@Fe3O4 core@shell nanowires (M = Cu, Co, CoO) 

      Tangarife, E. [Univ Mayor, Fac Ciencias, Ctr Nanotecnol Aplicada]; Mejia-López, J.; Mazo-Zuluaga, J. (ROYAL SOC CHEMISTRY, 2019)
      Interest in low dimensional magnetic systems has been growing due to the novel and dramatically differentiated effects of their physical properties, which give them special behaviors and uses in biomedical, environmental ...
    • Global ecological predictors of the soil priming effect 

      Abades, Sebastián [Univ Mayor, GEMA Ctr Genom Ecol & Environm]; Bowker, Matthew A. [Univ Mayor, GEMA Ctr Genom Ecol & Environm]; Bastida, Felipe; Bastidal, Felipe; Garcia, Carlos; Fierer, Noah; Eldridge, David J.; Alfaro, Fernando D.; Berhe, Asmeret Asefaw; Cutler, Nick A.; Gallardo, Antonio; Garcia-Velazquez, Laura; Hart, Stephen C.; Hayese, Patrick E.; Hernández, Teresa; Hseu, Zeng-Yei; Jehmlich, Nico; Kirchmair, Martin; Lambers, Hans; Neuhauser, Sigrid; Pena-Ramírez, Víctor M.; Pérez, Cecilia A.; Reed, Sasha C.; Santos, Fernanda; Siebe, Christina; Sullivan, Benjamin W.; Trivedi, Pankaj; Vera, Alfonso; Williams, Mark A.; Moreno, JoséLuis; Delgado-Baquerizo, Manuel (NATURE PUBLISHING GROUP, 2019)
      Identifying the global drivers of soil priming is essential to understanding C cycling in terrestrial ecosystems. We conducted a survey of soils across 86 globally-distributed locations, spanning a wide range of climates, ...
    • Bacterial community structure in a sympagic habitat expanding with global warming: brackish ice brine at 85-90 degrees N 

      Trefault, Nicole [Univ Mayor, GEMA Ctr Genom Ecol & Environm, Santiago, Chile]; Alfaro, Fernando D. [Univ Mayor, GEMA Ctr Genom Ecol & Environm, Santiago, Chile]; Fernández-Gómez, Beatriz; Diez, Beatriz; Polz, Martin F.; Ignacio Arroyo, Jose; Marchandon, German; Sanhueza, Cynthia; Farias, Laura; Marquet, Pablo A.; Molina-Montenegro, Marco A.; Sylvander, Peter; Snoeijs-Leijonmalm, Pauline (NATURE PUBLISHING GROUP, 2019)
      Larger volumes of sea ice have been thawing in the Central Arctic Ocean (CAO) during the last decades than during the past 800,000 years. Brackish brine (fed by meltwater inside the ice) is an expanding sympagic habitat ...
    • Summer phyto- and bacterioplankton communities during low and high productivity scenarios in the Western Antarctic Peninsula 

      Trefault, Nicole [Univ Mayor, Ctr Genom & Bioinformat, Fac Sci, Santiago, Chile]; Fuentes, Sebastián; Ignacio Arroyo, Jose; Rodríguez-Marconi, Susana; Masotti, Italo; Alarcón-Schumacher, Tomás; Polz, Martin F.; De la Iglesia, Rodrigo; Diez, Beatriz (SPRINGER, 2019)
      Phytoplankton blooms taking place during the warm season drive high productivity in Antarctic coastal seawaters. Important temporal and spatial variations exist in productivity patterns, indicating local constraints ...
    • Seabird and pinniped shape soil bacterial communities of their settlements in Cape Shirreff, Antarctica 

      Trefault, Nicole [Univ Mayor, Fac Sci, Ctr Gen Ecol & Environm GEMA, Santiago, Chile]; Ramírez-Fernández, Lia; Caru, Margarita; Orlando, Julieta (PUBLIC LIBRARY SCIENCE, 2019)
      Seabirds and pinnipeds play an important role in biogeochemical cycling by transferring nutrients from aquatic to terrestrial environments. Indeed, soils rich in animal depositions have generally high organic carbon, ...
    • Microplastic ingestion cause intestinal lesions in the intertidal fish Girella laevifrons 

      Galban-Malagón, C. [Univ Mayor, GEMA Ctr Genom Ecol & Environm]; Ahrendt, C.; Pérez-Venegas, D. J.; Urbina, M.; González, C.; Echeveste, P.; Aldana, M.; Pulgar, J. (PERGAMON-ELSEVIER SCIENCE LTD, 2020)
      We exposed juvenile intertidal fish to different amounts of Poly(styrene-co-divinylbenzene) microplastics in their diet. We fed ten individuals with pellets containing 0.01 g, another ten fish with pellets containing 0.1 ...
    • Two novel azaspiracids from Azadinium poporum, and a comprehensive compilation of azaspiracids produced by Amphidomataceae, (Dinophyceae) 

      Trefault, Nicole [Univ Mayor, Fac Sci, GEMA Ctr Genom Ecol & Environm]; Krock, Bernd; Tillmann, Urban; Tebben, Jan; Gu, Haifeng (ELSEVIER SCIENCE BV, 2019)
      Two novel azaspiracids (AZA) with a molecular mass of 869 Da were found in Pacific strains of Azadinium poporum and characterized by tandem mass spectrometry and high resolution mass spectrometry (HRMS). One compound, ...


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