Listar INVESTIGACIÓN por autor "Andrade, David C. [Univ Mayor, Ctr Invest Fisiol Ejercicio, Santiago, Chile]"
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Ablation of brainstem C1 neurons improves cardiac function in volume overload heart failure
Andrade, David C. [Univ Mayor, Ctr Invest Fisiol Ejercicio, Santiago, Chile]; Toledo, Camilo; Díaz, Hugo S.; Lucero, Claudia; Arce-Alvarez, Alexis; Oliveira, Luiz M.; Takakura, Ana C.; Moreira, Thiago S.; Schultz, Harold D.; Marcus, Noah J.; Alcayaga, Julio; Del Rio, Rodrigo (PORTLAND PRESS LTD, 2019)Activation of the sympathetic nervous system is a hallmark of heart failure (HF) and is positively correlated with disease progression. Catecholaminergic (C1) neurons located in the rostral ventrolateral medulla (RVLM) are ... -
Cognitive impairment in heart failure is associated with altered Wnt signaling in the hippocampus
Andrade, David C. [Univ Mayor, Ctr Invest Fisiol Ejercicio, Santiago, Chile]; Toledo, Camilo; Lucero, Claudia; Díaz, Hugo S.; Schwarz, Karla G.; Pereyra, Katherin V.; Arce-Alvarez, Alexis; López, Nicolás A.; Martínez, Milka; Inestrosa, Nibaldo C.; Del Rio, Rodrigo (IMPACT JOURNALS LLC, 2019)Age represents the highest risk factor for death due to cardiovascular disease. Heart failure (HF) is the most common cardiovascular disease in elder population and it is associated with cognitive impairment (CI), diminishing ... -
Heart rate variability alterations in infants with spontaneous hypertonia
Andrade, David C. [Univ Mayor, Ctr Invest Fisiol Ejercicio, Santiago, Chile]; Arce-Alvarez, Alexis; Melipillan, Claudia; Toledo, Camilo; Marcus, Noah J.; Del Rio, Rodrigo (NATURE PUBLISHING GROUP, 2019)BACKGROUND: Hypertonia is characterized by increased resting muscle tone. Previous studies have shown that adult patients with hypertonia displayed autonomic imbalance. However, cardiac sympathovagal control in infants ... -
Rostral ventrolateral medullary catecholaminergic neurones mediate irregular breathing pattern in volume overload heart failure rats
Andrade, David C. [Univ Mayor, Ctr Invest Fisiol Ejercicio, Santiago, Chile]; Toledo, Camilo; Díaz, Hugo S.; Pereyra, Katherin V.; Schwarz, Karla G.; Díaz-Jara, Esteban; Oliveira, Luiz M.; Takakura, Ana C.; Moreira, Thiago S.; Schultz, Harold D.; Marcus, Noah J.; Del Rio, Rodrigo (WILEY, 2019)Key points A strong association between disordered breathing patterns, elevated sympathetic activity, and enhanced central chemoreflex drive has been shown in experimental and human heart failure (HF). The aim of this study ...