Listar INVESTIGACIÓN por autor "Court, Felipe A. [Ctr Integrat Biol, Fac Sci, Universidad Mayor, Chile]"
Mostrando ítems 1-8 de 8
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A dual role for Integrin alpha 6 beta 4 in modulating hereditary neuropathy with liability to pressure palsies
Poitelon, Yannick; Matafora, Vittoria; Silvestri, Nicholas; Zambroni, Desiree; McGarry, Claire; Serghany, Nora; Rush, Thomas; Vizzuso, Domenica; Court, Felipe A. [Ctr Integrat Biol, Fac Sci, Universidad Mayor, Chile]; Bachi, Angela; Wrabetz, Lawrence; Feltri, María Laura (WILEY, 2018-05)Peripheral myelin protein 22 (PMP22) is a component of compact myelin in the peripheral nervous system. The amount of PMP22 in myelin is tightly regulated, and PMP22 over or under-expression cause Charcot-Marie-Tooth 1A ... -
Axonal Degeneration Is Mediated by Necroptosis Activation
Arrazola, Macarena S. [Ctr Integrat Biol, Fac Sci, Universidad Mayor, Chile]; Saquel, Cristián [Ctr Integrat Biol, Fac Sci, Universidad Mayor, Chile]; Catalán, Romina J. [Ctr Integrat Biol, Fac Sci, Universidad Mayor, Chile]; Barrientos, Sebastián A.; Hernández, Diego E.; Martínez, Nicolás W.; Catenaccio, Alejandra [Ctr Integrat Biol, Fac Sci, Universidad Mayor, Chile]; Court, Felipe A. [Ctr Integrat Biol, Fac Sci, Universidad Mayor, Chile] (SOC NEUROSCIENCE, 2019-05-15)Axonal degeneration, which contributes to functional impairment in several disorders of the nervous system, is an important target for neuroprotection. Several individual factors and subcellular events have been implicated ... -
Compartmentalized necroptosis activation in excitotoxicity-induced axonal degeneration: a novel mechanism implicated in neurodegenerative disease pathology
Arrazola, Macarena S. [Ctr Integrat Biol, Fac Sci, Universidad Mayor, Chile]; Court, Felipe A. [Ctr Integrat Biol, Fac Sci, Universidad Mayor, Chile] (WOLTERS KLUWER MEDKNOW PUBLICATIONS, 2019-08)Sin resumen. -
Correction: The necroptosis machinery mediates axonal degeneration in a model of Parkinson disease (vol 32, pg 274, 2019)
Oñate, Maritza [Ctr Integrat Biol, Fac Sci, Universidad Mayor, Chile]; Catenaccio, Alejandra [Ctr Integrat Biol, Fac Sci, Universidad Mayor, Chile]; Salvadores, Natalia [Ctr Integrat Biol, Fac Sci, Universidad Mayor, Chile]; Saquel, Cristian [Ctr Integrat Biol, Fac Sci, Universidad Mayor, Chile]; Martínez, Alexis; Moreno-González, Inés; Gamez, Nazaret; Soto, Paulina; Soto, Claudio; Hetz, Claudio; Court, Felipe A. [Ctr Integrat Biol, Fac Sci, Universidad Mayor, Chile] (Chile. Universidad Mayor, 2020-07)Correction to: Cell Death & Differentiation https://doi.org/10.1038/s41418-019-0408-4. Since online publication of this article, the authors noticed that reference details provided for references 65 and 66 were incorrect. ... -
In Vitro Analysis of the Role of Schwann Cells on Axonal Degeneration and Regeneration Using Sensory Neurons from Dorsal Root Ganglia
López-Leal, Rodrigo [Ctr Integrat Biol, Fac Sci, Universidad Mayor, Chile]; Díaz, Paula [Ctr Integrat Biol, Fac Sci, Universidad Mayor, Chile]; Court, Felipe A. [Ctr Integrat Biol, Fac Sci, Universidad Mayor, Chile] (Humana Press, 2018)Sensory neurons from dorsal root ganglion efficiently regenerate after peripheral nerve injuries. These neurons are widely used as a model system to study degenerative mechanisms of the soma and axons, as well as regenerative ... -
Purification of Exosomes from Primary Schwann Cells, RNA Extraction, and Next-Generation Sequencing of Exosomal RNAs
Gregorio, Cristian de [Ctr Integrat Biol, Fac Sci, Universidad Mayor, Chile]; Díaz, Paula [Ctr Integrat Biol, Fac Sci, Universidad Mayor, Chile]; López-Leal, Rodrigo [Ctr Integrat Biol, Fac Sci, Universidad Mayor, Chile]; Manque, Patricio [Ctr Integrat Biol, Fac Sci, Universidad Mayor, Chile]; Court, Felipe A. [Ctr Integrat Biol, Fac Sci, Universidad Mayor, Chile] (Humana Press, 2018)Exosomes are small (30-150 nm) vesicles of endosomal origin secreted by most cell types. Exosomes contain proteins, lipids, and RNA species including microRNA, mRNA, rRNA, and long noncoding RNAs. The mechanisms associated ... -
Teased Fiber Preparation of Myelinated Nerve Fibers from Peripheral Nerves for Vital Dye Staining and Immunofluorescence Analysis
Catenaccio, Alejandra [Ctr Integrat Biol, Fac Sci, Universidad Mayor, Chile]; Court, Felipe A. [Ctr Integrat Biol, Fac Sci, Universidad Mayor, Chile] (Humana Press, 2018)Glial cells regulate a wide variety of neuronal functions during physiological and pathological conditions. Therefore, the study of glial cells and their association with axons is of paramount importance in order to ... -
The necroptosis machinery mediates axonal degeneration in a model of Parkinson disease
Oñate, Maritza [Ctr Integrat Biol, Fac Sci, Universidad Mayor, Chile]; Catenaccio, Alejandra [Ctr Integrat Biol, Fac Sci, Universidad Mayor, Chile]; Salvadores, Natalia [Ctr Integrat Biol, Fac Sci, Universidad Mayor, Chile]; Saquel, Cristian [Ctr Integrat Biol, Fac Sci, Universidad Mayor, Chile]; Martínez, Alexis; Moreno-González, Inés; Gamez, Nazaret; Soto, Paulina; Soto, Claudio; Hetz, Claudio; Court, Felipe A. [Ctr Integrat Biol, Fac Sci, Universidad Mayor, Chile] (NATURE PUBLISHING GROUP, 2020-04)Parkinson's disease (PD) is the second most common neurodegenerative condition, characterized by motor impairment due to the progressive degeneration of dopaminergic neurons in the substantia nigra and depletion of dopamine ...