• Draft Genome Sequences of 40 Pathogenic Leptospira Strains Isolated from Cattle in Uruguay 

      Iraola, Gregorio [Univ Mayor, Ctr Integrat Biol, Santiago, Chile]; Nieves, Cecilia; Ferres, Ignacio; Díaz-Viraque, Florencia; Buschiazzo, Alejandro; Zarantonelli, Leticia (AMER SOC MICROBIOLOGY, 2019)
      Pathogenic Leptospira species represent a major concern for livestock but also for human health, as they cause zoonotic infections. Forty strains representing L. interrogans, L. borgpetersenii, and L. noguchii were isolated ...
    • Nanopore Sequencing Significantly Improves Genome Assembly of the Protozoan Parasite Trypanosoma cruzi 

      Iraola, Gregorio [Univ Mayor, Ctr Integrat Biol, Santiago, Chile]; Díaz-Viraque, Florencia; Pita, Sebastián; Greif, Gonzalo; Moreira De Souza, Rita de Cassia; Robello, Carlos (OXFORD UNIV PRESS, 2019)
      Chagas disease was described by Carlos Chagas, who first identified the parasite Trypanosoma cruzi from a 2-year-old girl called Berenice. Many T. cruzi sequencing projects based on short reads have demonstrated that genome ...
    • Schwann cell reprogramming into repair cells increases miRNA-21 expression in exosomes promoting axonal growth 

      López-Leal, Rodrigo [Univ Mayor, Fac & Sci, Ctr Integrat Biol, Chile]; Díaz-Viraque, Florencia; Catalán, Romina J. [Univ Mayor, Fac & Sci, Ctr Integrat Biol, Chile]; Saquel, Cristian [Univ Mayor, Fac & Sci, Ctr Integrat Biol, Chile]; Enright, Anton; Iraola, Gregorio [Univ Mayor, Fac & Sci, Ctr Integrat Biol, Chile]; Court, Felipe A. [Univ Mayor, Fac Sci, Ctr Integrat Biol, Chile] (Company of Biologists Ltd, 2020-06)
      Functional recovery after peripheral nerve damage is dependent on the reprogramming of differentiated Schwann cells (dSCs) into repair Schwann cells (rSCs), which promotes axonal regeneration and tissue homeostasis. ...
    • The Tritryps Comparative Repeatome: Insights on Repetitive Element Evolution in Trypanosomatid Pathogens 

      Iraola, Gregorio [Univ Mayor, Ctr Biol Integrat, Santiago, Chile]; Pita, Sebastián; Díaz-Viraque, Florencia; Robello, Carlos (SPRINGER, 2019)
      The major human pathogens Trypanosoma cruzi, Trypanosoma brucei, and Leishmania major are collectively known as the Tritryps. The initial comparative analysis of their genomes has uncovered that Tritryps share a great ...


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