• Gene Regulatory Networks of Penicillium echinulatum 2HH and Penicillium oxalicum 114-2 Inferred by a Computational Biology Approach 

      Lenz, Alexandre Rafael; Galán-Vásquez, Edgardo; Balbinot, Eduardo; de Abreu, Fernanda Pessi; Souza de Oliveira, Nikael; da Rosa, Leticia Osorio; de Avila e Silva, Scheila; Camassola, Marli; Dillon, Aldo Jose Pinheiro; Pérez-Rueda, Ernesto [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Chile] (Frontiers Media S.A., 2020-10)
      Penicillium echinulatum 2HH and Penicillium oxalicum 114-2 are well-known cellulase fungal producers. However, few studies addressing global mechanisms for gene regulation of these two important organisms are available so ...
    • Identification of Modules With Similar Gene Regulation and Metabolic Functions Based on Co-expression Data 

      Pérez-Rueda, Ernesto [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Santiago, Chile]; Galán-Vásquez, Edgardo (FRONTIERS MEDIA SA, 2019)
      Biological systems respond to environmental perturbations and to a large diversity of compounds through gene interactions, and these genetic factors comprise complex networks. In particular, a wide variety of gene co-expression ...
    • The protein architecture in Bacteria and Archaea identifies a set of promiscuous and ancient domains 

      Hernández-Guerrero, Rafael; Galán-Vásquez, Edgardo; Pérez-Rueda, Ernesto [Centro de Genómica y Bioinformática, Facultad de Ciencias, Universidad Mayor, Chile] (Public Library of Science, 2019-12-19)
      In this work, we describe a systematic comparative genomic analysis of promiscuous domains in genomes of Bacteria and Archaea. A quantitative measure of domain promiscuity, the weighted domain architecture score (WDAS), ...


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