Listar INVESTIGACIÓN por autor "Hernández-Guerrero, Rafael"
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Deciphering the functional diversity of DNA-binding transcription factors in Bacteria and Archaea organisms
Flores-Bautista, Emanuel; Hernández-Guerrero, Rafael; Huerta-Saquero, Alejandro; Tenorio-Salgado, Silvia; Rivera-Gómez, Nancy; Romero, Alba; Antonio Ibarra, José; Pérez-Rueda, Ernesto [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Chile] (Public Library of Science, 2020-08)DNA-binding Transcription Factors (TFs) play a central role in regulation of gene expression in prokaryotic organisms, and similarities at the sequence level have been reported. These proteins are predicted with different ... -
Evaluation of the Abundance of DNA-Binding Transcription Factors in Prokaryotes
Pérez-Rueda, Ernesto [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat]; Sánchez, Israel; Hernández-Guerrero, Rafael; Méndez-Monroy, Paul Erick; Martínez-Nunez, Mario Alberto; Ibarra, JoséAntonio (MDPI, 2020)The ability of bacteria and archaea to modulate metabolic process, defensive response, and pathogenic capabilities depend on their repertoire of genes and capacity to regulate the expression of them. Transcription factors ... -
Identification of functional signatures in the metabolism of the three cellular domains of life
Pérez-Rueda, Ernesto {Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Santiago, Chile]; Escobar-Turriza, Pedro; Hernández-Guerrero, Rafael; César Poot-Hernández, Augusto; Rodríguez-Vazquez, Katya; Ramírez-Prado, Jorge (PUBLIC LIBRARY SCIENCE, 2019)In order to identify common and specific enzymatic activities associated with the metabolism of the three cellular domains of life, the conservation and variations between the enzyme contents of Bacteria, Archaea, and ... -
The protein architecture in Bacteria and Archaea identifies a set of promiscuous and ancient domains
Hernández-Guerrero, Rafael; Galán-Vásquez, Edgardo; Pérez-Rueda, Ernesto [Centro de Genómica y Bioinformática, Facultad de Ciencias, Universidad Mayor, Chile] (Public Library of Science, 2019-12-19)In this work, we describe a systematic comparative genomic analysis of promiscuous domains in genomes of Bacteria and Archaea. A quantitative measure of domain promiscuity, the weighted domain architecture score (WDAS), ...