| dc.contributor | PERGAMON-ELSEVIER SCIENCE LTD. | es_CL |
| dc.contributor.author | Tevy, Maria Florencia [Chile. Universidad Mayor. Centro de Genómica y Bioinformática] | es_CL |
| dc.contributor.author | Borghesan, Michela [IRCCS Scientific Institute] | es_CL |
| dc.contributor.author | Delle Vergini, Maria Rita [IRCCS Scientific Institute] | es_CL |
| dc.contributor.author | Vinciguerra, Manlio [IRCCS Scientific Institute] | es_CL |
| dc.date.accessioned | 2018-09-07T13:04:13Z | |
| dc.date.available | 2018-09-07T13:04:13Z | |
| dc.date.issued | 2014 | es_CL |
| dc.identifier.citation | Mazzoccoli, G., Tevy, M. F., Borghesan, M., Delle Vergini, M. R., & Vinciguerra, M. (2014). Caloric restriction and aging stem cells: the stick and the carrot?. Experimental gerontology, 50, 137-148. | es_CL |
| dc.identifier.issn | ISSN 0531-5565 | es_CL |
| dc.identifier.issn | ESSN 1873-6815 | es_CL |
| dc.identifier.uri | https://ac.els-cdn.com/S0531556513003185/1-s2.0-S0531556513003185-main.pdf?_tid=2908ba21-3f3a-4c57-bad7-ba9e761e6763&acdnat=1536093778_82f8a05fcf191d5a5926c5d1b081075f | es_CL |
| dc.identifier.uri | https://doi.org/10.1016/j.exger.2013.10.014 | es_CL |
| dc.identifier.uri | http://repositorio.umayor.cl/xmlui/handle/sibum/2646 | |
| dc.description.abstract | Adult tissue stem cells have the ability to adjust to environmental changes and affect also the proliferation of neighboring cells, with important consequences on tissue maintenance and regeneration. Stem cell renewal and proliferation is strongly regulated during aging of the organism. Caloric restriction is the most powerful anti-aging strategy conserved throughout evolution in the animal kingdom. Recent studies relate the properties of caloric restriction to its ability in reprogramming stem-like cell states and in prolonging the capacity of stem cells to self-renew, proliferate, differentiate, and replace cells in several adult tissues. However this general paradigm presents with exceptions. The scope of this review is to highlight how caloric restriction impacts on diverse stem cell compartments and, by doing so, might differentially delay aging in the tissues of lower and higher organisms. | es_CL |
| dc.description.sponsorship | Este trabajo fue financiado por: "5x1000" contribuciones voluntarias; Italian Ministry of Health (grants RC1203ME46, RC1302ME31); Department of Medical Sciences, Division of Internal Medicine and Chronobiology Unit, IRCCS Scientific Institute and Regional General Hospital "Casa Sollievo della Sofferenza", Opera di Padre Pio da Pietrelcina, San Giovanni Rotondo; Grant (MFAG-AIRC 2012-13419) Italian Association for Cancer Research (AIRC). | es_CL |
| dc.format.extent | REVISIÓN | es_CL |
| dc.language.iso | en | es_CL |
| dc.publisher | CIENCIAS | es_CL |
| dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Chile | es_CL |
| dc.subject | GERIATRIA | es_CL |
| dc.title | Caloric restriction and aging stem cells: The stick and the carrot? | es_CL |
| dc.type | Artículo o Paper | es_CL |
| umayor.indizador | COT | es_CL |
| umayor.politicas.sherpa/romeo | Licencia color: VERDE C/R (Se puede archivar el pre-print y el post-print o versión de editor/PDF, el autor no puede archivar la versión del editor/PDF)--Pre-print del autor: el autor puede archivar la versión pre-print (ie la versión previa a la revisión por pares) Post-print del autor: el autor puede archivar la versión post-print (ie la versión final posterior a la revisión por pares) Versión de editor/PDF: el autor no puede archivar la versión del editor/PDF. Condiciones generales: Authors pre-print on any website, including arXiv and RePEC, Author's post-print on author's personal website immediately, Author's post-print on open access repository after an embargo period of between 12 months and 48 months, Permitted deposit due to Funding Body, Institutional and Governmental policy or mandate, may be required to comply with embargo periods of 12 months to 48 months, Author's post-print may be used to update arXiv and RepEC, La versión de editor/PDF no puede utilizarse, Debe enlazar a la versión de editor con DOI, Author's post-print must be released with a Creative Commons Attribution Non-Commercial No Derivatives License// Disponible en: http://www.sherpa.ac.uk/romeo/issn/0531-5565/es/ | es_CL |
| umayor.indexado | WOS | es_CL |
| umayor.indexado | SCOPUS | es_CL |
| dc.identifier.doi | 10.1016/j.exger.2013.10.014 | es_CL] |
| umayor.indicadores.wos-(cuartil) | Q2 | es_CL |
| umayor.indicadores.scopus-(scimago-sjr) | sin información | es_CL |