| dc.contributor | MOSBY-ELSEVIER | es_CL |
| dc.contributor.author | Pabst, Carolina [Chile. Universidad Mayor] | es_CL |
| dc.contributor.author | Martínez, Benjamín [Chile. Universidad Mayor] | es_CL |
| dc.contributor.author | Hernández, Marcela [Universidad de Chile] | es_CL |
| dc.date.accessioned | 2018-09-07T14:11:38Z | |
| dc.date.available | 2018-09-07T14:11:38Z | |
| dc.date.issued | 2008 | es_CL |
| dc.identifier.citation | Belmar, M. J., Pabst, C., Martínez, B., & Hernández, M. (2008). Gelatinolytic activity in gingival crevicular fluid from teeth with periapical lesions. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 105(6), 801-806. | es_CL |
| dc.identifier.issn | ISSN 1079-2104 | es_CL |
| dc.identifier.uri | https://ac.els-cdn.com/S1079210407009146/1-s2.0-S1079210407009146-main.pdf?_tid=f9691b63-c801-4719-9c09-5ad038c94943&acdnat=1536082967_08fd5c02472e0083ba7265f1c603c315 | es_CL |
| dc.identifier.uri | https://doi.org/10.1016/j.tripleo.2007.12.002 | es_CL |
| dc.identifier.uri | http://repositorio.umayor.cl/xmlui/handle/sibum/2692 | |
| dc.description.abstract | Objective. Many matrix metalloproteinases ( MMPs) have been associated with periodontal tissue destruction during chronic and apical periodontitis. The aim of this study was to determine gelatinolytic activity in gingival crevicular fluid (GCF) from teeth with apical lesions and healthy controls. Study design. Case-control study. Materials and methods. After clinical examination, 30 GCF samples were obtained from 20 affected and 20 control teeth. Subjects with periodontal diseases were excluded. Gelatinolytic activity was determined by gelatin zymography and densitometric analysis. Results. ProMMP-9 levels were significantly increased when compared with controls and were positively correlated with MMP-9 activity in diseased GGF. Similarly, MMP-2 activity, when detected it was exclusively in diseased samples. Additional bands of estimated molecular weights of 60 and 48 kDa were observed. Conclusions. MMP-9 and -2 are highly increased in GCF from teeth with periapical lesions. These gelatinases could represent useful markers in monitoring chronic apical periodontitis in GCF. | es_CL |
| dc.description.sponsorship | Este trabajo no contó con financiamiento. | es_CL |
| dc.format.extent | ARTÍCULO ORIGINAL | es_CL |
| dc.language.iso | en | es_CL |
| dc.publisher | CIENCIAS | es_CL |
| dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Chile | es_CL |
| dc.subject | ODONTOLOGÍA | es_CL |
| dc.title | Gelatinolytic activity in gingival crevicular fluid from teeth with periapical lesions | es_CL |
| dc.type | Artículo o Paper | es_CL |
| umayor.indizador | COT | es_CL |
| umayor.politicas.sherpa/romeo | Licencia color: VERDE C/R (Se puede archivar el pre-print y el post-print o versión de editor/PDF, el autor no puede archivar la versión del editor/PDF)--Pre-print del autor: el autor puede archivar la versión pre-print (ie la versión previa a la revisión por pares) Post-print del autor: el autor puede archivar la versión post-print (ie la versión final posterior a la revisión por pares) Versión de editor/PDF: el autor no puede archivar la versión del editor/PDF. Condiciones generales: Authors pre-print on any website, including arXiv and RePEC, Author's post-print on author's personal website immediately, Author's post-print on open access repository after an embargo period of between 12 months and 48 months, Permitted deposit due to Funding Body, Institutional and Governmental policy or mandate, may be required to comply with embargo periods of 12 months to 48 months, Author's post-print may be used to update arXiv and RepEC, La versión de editor/PDF no puede utilizarse, Debe enlazar a la versión de editor con DOI, Author's post-print must be released with a Creative Commons Attribution Non-Commercial No Derivatives License// Disponible en: http://www.sherpa.ac.uk/romeo/issn/1079-2104/es/ | es_CL |
| umayor.indexado | WOS | es_CL |
| dc.identifier.doi | 10.1016/j.tripleo.2007.12.002 | es_CL] |
| umayor.indicadores.wos-(cuartil) | Q2 | es_CL |
| umayor.indicadores.scopus-(scimago-sjr) | sin información | es_CL |