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| dc.contributor | Elsevier | es_CL |
| dc.contributor.author | Calixto, Andrea [Chile. Universidad Mayor. Facultad de Ciencias. Centro de Genómica y Bioinformática] | es_CL |
| dc.date.accessioned | 2018-09-07T14:11:41Z | |
| dc.date.available | 2018-09-07T14:11:41Z | |
| dc.date.issued | 2015 | es_CL |
| dc.identifier.citation | Calixto, A. (2015). Life without Food and the Implications for Neurodegeneration. In: Friedmann, Theodore; Jay C. Dunlap; Stephen F. Goodwin. Advances in genetics (Vol. 92, pp. 53-74). Academic Press. | es_CL |
| dc.identifier.issn | ISSN: 0065-2660 | es_CL |
| dc.identifier.uri | https://www.sciencedirect.com/science/article/pii/S006526601500036X | es_CL |
| dc.identifier.uri | https://doi.org/10.1016/bs.adgen.2015.09.004 | es_CL |
| dc.identifier.uri | http://repositorio.umayor.cl/xmlui/handle/sibum/2721 | |
| dc.description.abstract | Food availability determines developmental rate, behavior, and survival of animals. Animals that enter diapause or hibernate in response to lack of food have a double advantage: they are able to adapt to environmental and cellular challenges and survive to these challenges for a prolonged time. The metabolic and physiological adaptations that make possible diapause and hibernation also provide a favorable cellular environment for tissue protection. This review highlights the benefits of dormancy on neuronal protection in the model organism Caenorhabditis elegans and small mammals such as squirrels. Additionally, I discuss the link between metabolic restructuring occurring in diapause and changes in gene expression with the increased capacity of diapausing animals to protect neurons from degeneration and potentially foster their regeneration. | es_CL |
| dc.description.sponsorship | Este trabajo no contó con financiamiento. | es_CL |
| dc.format.extent | CAPÍTULO DE LIBRO | es_CL |
| dc.language.iso | en | es_CL |
| dc.publisher | CIENCIAS | es_CL |
| dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Chile | es_CL |
| dc.subject | GENÉTICA | es_CL |
| dc.title | Life without Food and the Implications for Neurodegeneration | es_CL |
| dc.type | Artículo o Paper | es_CL |
| umayor.indizador | COT | es_CL |
| umayor.politicas.sherpa/romeo | Licencia color: VERDE C/R (Se puede archivar el pre-print y el post-print o versión de editor/PDF, el autor no puede archivar la versión del editor/PDF)--Authors pre-print on any website, including arXiv and RePEC Author's post-print on author's personal website immediately Author's post-print on open access repository after an embargo period of between 12 months and 48 months Permitted deposit due to Funding Body, Institutional and Governmental policy or mandate, may be required to comply with embargo periods of 12 months to 48 months Author's post-print may be used to update arXiv and RepEC La versión de editor/PDF no puede utilizarse Debe enlazar a la versión de editor con DOI Author's post-print must be released with a Creative Commons Attribution Non-Commercial No Derivatives License// Disponible en: http://www.sherpa.ac.uk/romeo/issn/0065-2660/es/ | es_CL |
| umayor.indexado | WOS | es_CL |
| umayor.indexado | SCOPUS | es_CL |
| dc.identifier.doi | 10.1016/bs.adgen.2015.09.004 | es_CL] |
| umayor.indicadores.wos-(cuartil) | Q1 | es_CL |
| umayor.indicadores.scopus-(scimago-sjr) | sin información | es_CL |
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