Show simple item record

dc.contributorSpandidos Publ.es_CL
dc.contributor.authorCalaf , G. M. [Chile. Universidad de Tarapacá]es_CL
dc.contributor.authorBadinez, Leonardo [Chile. Instituto Nacional del Cáncer]es_CL
dc.date.accessioned2018-09-07T14:11:44Z
dc.date.available2018-09-07T14:11:44Z
dc.date.issued2009es_CL
dc.identifier.citationMurray, N. P., Calaf, G. M., & Badinez, L. (2009). Presence of prostate cells in bone marrow biopsies as a sign of micrometastasis in cancer patients. Oncology reports, 21(3), 571-575.es_CL
dc.identifier.issnISSN 1021-335Xes_CL
dc.identifier.issnESSN 1791-2431es_CL
dc.identifier.urihttps://www.spandidos-publications.com/or/21/3/571/downloades_CL
dc.identifier.urihttps://doi.org/10.3892/or_00000258es_CL
dc.identifier.urihttp://repositorio.umayor.cl/xmlui/handle/sibum/2758
dc.description.abstractThe presence of prostate cancer cells in bone marrow of patients with clinically localized disease is associated with increased chance of disease recurrence. The presence of prostate specific antigen (PSA) in bone marrow aspirates has been used to indicate the presence of micrometastasis. The aim of this study was to present a prospective study of prostate cancer patients to determine the presence of cells that express PSA in aspirates taken from bone marrow and to compare with bone marrow biopsy samples. Results indicated a significant difference between the frequency of cells detected in bone marrow aspirate and biopsy samples (P<0.0002) when all patients were considered. There was no difference between the frequencies of cells detected in bone marrow aspirate and biopsy of patients analyzed before treatment. However, there was a significant (P<0.003) difference between them after treatment. There was also a significant difference in the frequency of PSA positive cells detected (P<0.005) in Stages I to IV as well as in the frequency of cells detected (P<0.0002) when analyzed according to Gleason score. The present results explain the lack of correlation between positive aspirates and prognosis in numerous clinical cases.es_CL
dc.description.sponsorshipEste trabajo no contó con financiamiento.es_CL
dc.format.extentARTÍCULO ORIGINALes_CL
dc.language.isoenes_CL
dc.publisherCIENCIASes_CL
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chilees_CL
dc.subjectONCOLOGÍAes_CL
dc.titlePresence of prostate cells in bone marrow biopsies as a sign of micrometastasis in cancer patientses_CL
dc.typeArtículo o Paperes_CL
umayor.indizadorCOTes_CL
umayor.politicas.sherpa/romeoLicencia color: BLANCO (El archivo no está formalmente admitido)--Pre-print del autor: el autor no puede archivar la versión pre-print (ie la versión previa a la revisión por pares) Post-print del autor: el autor no puede archivar la versión post-print (ie la versión final posterior a la revisión por pares) Versión de editor/PDF: grey tick el autor puede archivar la versión PDF de la editorial siempre que se cumplan las restricciones: 6 meses de embargo Condiciones generales: La versión de editor/PDF debe utilizarse, On Institutional Repository or Funder's repository, Debe ir enlazado a la versión de editor, La fuente publicada debe reconocerse con la cita completa, Publisher will automatically deposit authors post-print in PubMed Central or Europe PMC after 6 months or 12 months as required by funding agency// Disponible en: http://www.sherpa.ac.uk/romeo/issn/1021-335X/es/es_CL
umayor.indexadoWOSes_CL
dc.identifier.doi10.3892/or_00000258es_CL]
umayor.indicadores.wos-(cuartil)Q3es_CL
umayor.indicadores.scopus-(scimago-sjr)sin informaciónes_CL


Show simple item record