| dc.contributor.author | Fuentes-Barros, Gonzalo [Univ Mayor, Escuela Ingn Forestal, Santiago, Chile] | es_CL |
| dc.contributor.author | Castro-Saavedra, Sebastián [Univ Mayor, Escuela Ingn Forestal, Santiago, Chile] | es_CL |
| dc.contributor.author | Liberona, Leonel | es_CL |
| dc.contributor.author | Acevedo-Fuentes, Williams | es_CL |
| dc.contributor.author | Tirapegui, Cristián | es_CL |
| dc.contributor.author | Mattar, César | es_CL |
| dc.contributor.author | Cassels, Bruce K. | es_CL |
| dc.date.accessioned | 2020-04-08T14:11:55Z | |
| dc.date.accessioned | 2020-04-13T18:12:38Z | |
| dc.date.available | 2020-04-08T14:11:55Z | |
| dc.date.available | 2020-04-13T18:12:38Z | |
| dc.date.issued | 2018 | es_CL |
| dc.identifier.citation | Fuentes-Barros, G., Castro-Saavedra, S., Liberona, L., Acevedo-Fuentes, W., Tirapegui, C., Mattar, C., & Cassels, B. K. (2018). Variation of the alkaloid content of Peumus boldus (boldo). Fitoterapia, 127, 179-185. | es_CL |
| dc.identifier.issn | 0367-326X | es_CL |
| dc.identifier.issn | 1873-6971 | es_CL |
| dc.identifier.uri | https://doi.org/10.1016/j.fitote.2018.02.020 | es_CL |
| dc.identifier.uri | http://repositorio.umayor.cl/xmlui/handle/sibum/6133 | |
| dc.description.abstract | Eighteen alkaloids were detected in the bark, leaves, wood and roots of Peumus boldus, including traces of secoboldine, N-methylsecoboldine (boldine methine), glaucine and norreticuline, not reported previously as constituents of this species. Using appropriate standards, we quantified thirteen of them by UHPLC-MS/MS. Boldine was dominant in the bark, and laurolitsine in wood and roots. The alkaloid composition of the leaves, determined for 130 individually identified trees, classified by age and sex, was highly variable, where N-methyllaurotetanine, laurotetanine, coclaurine and in some cases isocorydine predominated, but not boldine. | es_CL |
| dc.description.sponsorship | Fondo de Investigacion del Bosque Nativo (CONAF) [055/2013] | es_CL |
| dc.description.sponsorship | Thanks are due to the Fondo de Investigacion del Bosque Nativo (CONAF) for grant No 055/2013, and Dr. Estefania Hugo for the synthesis of norreticuline, and Dr. Edwin G. Pérez of the Facultad de Quimica de la Pontificia Universidad Catolica de Chile for a gift of N-methyllaurotetanine. | es_CL |
| dc.language.iso | en | es_CL |
| dc.publisher | ELSEVIER SCIENCE BV | es_CL |
| dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Chile | |
| dc.source | Fitoterapia, JUN 2018. 127: p. 179-185 | |
| dc.subject | Chemistry, Medicinal; Pharmacology & Pharmacy | es_CL |
| dc.title | Variation of the alkaloid content of Peumus boldus (boldo) | es_CL |
| dc.type | Artículo | es_CL |
| umayor.facultad | CIENCIAS | es_CL |
| umayor.politicas.sherpa/romeo | RoMEO green journal (Se puede archivar el pre-print y el post-print o versión de editor/PDF). Disponible en: http://sherpa.ac.uk/romeo/index.php | es_CL |
| umayor.indexado | WOS:000437551000027 | es_CL |
| umayor.indexado | PMID: 29454020 | es_CL |
| dc.identifier.doi | DOI: 10.1016/j.fitote.2018.02.020 | es_CL] |
| umayor.indicadores.wos-(cuartil) | Q3 | es_CL |
| umayor.indicadores.scopus-(scimago-sjr) | SCIMAGO/ INDICE H: 90 H | es_CL |