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dc.contributor.authorCastillo-Carniglia, Alvaro [Univ Mayor, Fac Humanidades, Soc & Hlth Res Ctr]es_CL
dc.contributor.authorPonicki, William R.es_CL
dc.contributor.authorGaidus, Andrewes_CL
dc.contributor.authorGruenewald, Paul J.es_CL
dc.contributor.authorMarshall, Brandon D. L.es_CL
dc.contributor.authorFink, David S.es_CL
dc.contributor.authorMartins, Silvia S.es_CL
dc.contributor.authorRivera-Aguirre, Ariadnees_CL
dc.contributor.authorWintemute, Garen J.es_CL
dc.contributor.authorCerda, Magdalenaes_CL
dc.date.accessioned2020-04-12T14:11:55Z
dc.date.accessioned2020-04-14T15:37:42Z
dc.date.available2020-04-12T14:11:55Z
dc.date.available2020-04-14T15:37:42Z
dc.date.issued2019es_CL
dc.identifier.citationCastillo-Carniglia, A., Ponicki, W. R., Gaidus, A., Gruenewald, P. J., Marshall, B. D., Fink, D. S., ... & Cerdá, M. (2019). Prescription drug monitoring programs and opioid overdoses: exploring sources of heterogeneity. Epidemiology, 30(2), 212-220.es_CL
dc.identifier.issn1044-3983es_CL
dc.identifier.issn1531-5487es_CL
dc.identifier.urihttps://cdn.journals.lww.com/epidem/Abstract/2019/03000/Prescription_Drug_Monitoring_Programs_and_Opioid.9.aspxes_CL
dc.identifier.urihttp://repositorio.umayor.cl/xmlui/handle/sibum/6431
dc.description.abstractBackground: Prescription drug monitoring program are designed to reduce harms from prescription opioids; however, little is known about what populations benefit the most from these programs. We investigated how the relation between implementation of online prescription drug monitoring programs and rates of hospitalizations related to prescription opioids and heroin overdose changed over time, and varied across county levels of poverty and unemployment, and levels of medical access to opioids. Methods: Ecologic county-level, spatiotemporal study, including 990 counties within 16 states, in 2001-2014. We modeled overdose counts using Bayesian hierarchical Poisson models. We defined medical access to opioids as the county-level rate of hospital discharges for noncancer pain conditions. Results: In 2010-2014, online prescription drug monitoring programs were associated with lower rates of prescription opioid-related hospitalizations (rate ratio 2014 = 0.74; 95% credible interval = 0.69, 0.80). The association between online prescription drug monitoring programs and heroin-related hospitalization was also negative but tended to increase in later years. Counties with lower rates of noncancer pain conditions experienced a lower decrease in prescription opioid overdose and a faster increase in heroin overdoses. No differences were observed across different county levels of poverty and unemployment. Conclusions: Areas with lower levels of noncancer pain conditions experienced the smallest decrease in prescription opioid overdose and the faster increase in heroin overdose following implementation of online prescription drug monitoring programs. Our results are consistent with the hypothesis that prescription drug monitoring programs are most effective in areas where people are likely to access opioids through medical providers.es_CL
dc.description.sponsorshipUS National Institute on Drug AbuseUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) - USANIH National Institute on Drug Abuse (NIDA) [R01DA039962, T32DA031099]; Becas Chile as part of the National Commission for Scientific and Technological Research (CONICYT); Robertson Fellowship in Violence Prevention Researches_CL
dc.description.sponsorshipSupported by grants from the US National Institute on Drug Abuse (R01DA039962, primary investigator, Dr. Cerda; T32DA031099, Fink). A.C.-C. was supported by Becas Chile as part of the National Commission for Scientific and Technological Research (CONICYT) and a Robertson Fellowship in Violence Prevention Research.es_CL
dc.language.isoenes_CL
dc.publisherLIPPINCOTT WILLIAMS & WILKINSes_CL
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
dc.sourceEpidemiology, MAR, 2019. 30(2): p. 212-220
dc.subjectPublic, Environmental & Occupational Healthes_CL
dc.titlePrescription Drug Monitoring Programs and Opioid Overdoses Exploring Sources of Heterogeneityes_CL
dc.typeArtículoes_CL
umayor.facultadCIENCIAS
umayor.politicas.sherpa/romeoGreen Acceptedes_CL
umayor.indexadoWOS:000458417200015es_CL
umayor.indexadoPMID: 30721165es_CL
dc.identifier.doiDOI: 10.1097/EDE.0000000000000950es_CL]
umayor.indicadores.wos-(cuartil)Q1es_CL
umayor.indicadores.scopus-(scimago-sjr)SCIMAGO/ INDICE H: 155 Hes_CL


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