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dc.contributor.authorIraola, Gregorio [Univ Mayor, Ctr Integrat Biol]es_CL
dc.contributor.authorFerres, Ignacioes_CL
dc.contributor.authorFresia, Pabloes_CL
dc.date.accessioned2020-04-12T14:11:55Z
dc.date.accessioned2020-04-14T15:37:46Z
dc.date.available2020-04-12T14:11:55Z
dc.date.available2020-04-14T15:37:46Z
dc.date.issued2020es_CL
dc.identifier.citationFerrés, I., Fresia, P., & Iraola, G. (2020). simurg: simulate bacterial pangenomes in R. Bioinformatics, 36(4), 1273-1274.es_CL
dc.identifier.issn1367-4803es_CL
dc.identifier.issn1460-2059es_CL
dc.identifier.urihttps://doi.org/10.1093/bioinformatics/btz735es_CL
dc.identifier.urihttp://repositorio.umayor.cl/xmlui/handle/sibum/6469
dc.description.abstractMotivation: The pangenome concept describes genetic variability as the union of genes shared in a set of genomes and constitutes the current paradigm for comparative analysis of bacterial populations. However, there is a lack of tools to simulate pangenome variability and structure using defined evolutionary models. Results: We developed simurg, an R package that allows to simulate bacterial pangenomes using different combinations of evolutionary constraints such as gene gain, gene loss and mutation rates. Our tool allows the straightforward and reproducible simulation of bacterial pangenomes using real sequence data, providing a valuable tool for benchmarking of pangenome software or comparing evolutionary hypotheses.es_CL
dc.description.sponsorshipAgencia Nacional de Investigacion e Innovacion (ANII) [POS_NAC_2018_1_151494]es_CL
dc.description.sponsorshipThis work was partially funded by the Agencia Nacional de Investigacion e Innovacion (ANII) [POS_NAC_2018_1_151494 to I.F.].es_CL
dc.language.isoenes_CL
dc.publisherOXFORD UNIV PRESSes_CL
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
dc.sourceBioinformatics, FEB, 2020. 36(4): p. 1273-1274
dc.subjectBiochemical Research Methods; Biotechnology & Applied Microbiology; Computer Science, Interdisciplinary Applications; Mathematical & Computational Biology; Statistics & Probabilityes_CL
dc.titleSimurg: simulate bacterial pangenomes in Res_CL
dc.typeArtículoes_CL
umayor.facultadCIENCIAS
umayor.politicas.sherpa/romeoRoMEO green journal (Se puede archivar el pre-print y el post-print o versión de editor/PDF). Disponible en: http://sherpa.ac.uk/romeo/index.phpes_CL
umayor.indexadoWOS:000518528800043es_CL
umayor.indexadoPMID: 31584605es_CL
dc.identifier.doiDOI: 10.1093/bioinformatics/btz735es_CL]
umayor.indicadores.wos-(cuartil)Q1es_CL
umayor.indicadores.scopus-(scimago-sjr)SCIMAGO/ INDICE H: 335 Hes_CL


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