Now showing items 1-2 of 2

    • Impaired IRE1 alpha/XBP-1 pathway associated to DNA methylation might contribute to salivary gland dysfunction in Sjogren's syndrome patients 

      González, Sergio [Univ Mayor, Fac Ciencias, Escuela Odontol, Santiago, Chile]; Molina, Claudio [Univ Mayor, Fac Ciencias, Dept Patol Oral, Escuela Odontol, Santiago, Chile]; Sepúlveda, Denisse; Barrera, María-José; Castro, Isabel; Aguilera, Sergio; Carvajal, Patricia; Lagos, Carolina; Albornoz, Nicolás; Bahamondes, Verónica; Quest, Andrew F. G.; Urzua, Ulises; Leyton, Cecilia; Hermoso, Marcela A.; González, María-Julieta (OXFORD UNIV PRESS, 2018)
      Objectives. Labial salivary glands (LSGs) of SS patients show alterations related to endoplasmic reticulum stress. Glandular dysfunction could be partly the consequence of an altered inositol-requiring enzyme 1 alpha (IRE1 ...
    • The integrated stress response is activated in the salivary glands of Sjogren's syndrome patients 

      Carvajal, Patricia; Bahamondes, Verónica; Jara, Daniela; Castro, Isabel; Matus, Soledad; Aguilera, Sergio; Molina, Claudio; González, Sergio [Univ Mayor, Escuela Odontol, Fac Med & Ciencias Salud, Chile]; Hermoso, Marcela; Barrera, María-José; González, María-Julieta (FRONTIERS MEDIA SA, 2023-03-23)
      IntroductionPrimary Sjogren's syndrome (SS) is an autoimmune exocrinopathy that affects the structure and function of salivary and lachrymal glands. Labial salivary gland (LSG) acinar cells from SS patients lose cellular ...


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