• Altered potassium channel distribution and composition in myelinated axons suppresses hyperexcitability following injury 

      Richards, Natalie [Wolfson Centre for Age-Related Diseases, Kings College London, London,United Kingdom]; Schmid, Annina B. [University of Oxford, Oxford. Nuffield Department of Clinical Neurosciences]; Barroso, Alejandro [Reino Unido. Wolfson Centre for Age-Related Diseases]; Zhu, Lan [Reino Unido. Wolfson Centre for Age-Related Diseases]; Ivulic, Dinka [Pontificia Universidad Católica de Chile]; Zhu, Ning [Reino Unido. University of Oxford. Nuffield Department of Clinical Neurosciences]; Anwandter, Philipp [Pontificia Universidad Católica de Chile]; Manzoor, Bhat A. [Estados Unidos. UT Health Science Center at San Antonio] (CIENCIAS, 2016)
      Neuropathic pain following peripheral nerve injury is associated with hyperexcitability in damaged myelinated sensory axons, which begins to normalise over time. We investigated the composition and distribution of ...
    • FBN-1, a fibrillin-related protein, is required for resistance ofthe epidermis to mechanical deformation during c. Elegans embryogenesis 

      Yochem, John [University of Wyoming. Department of Molecular Biology]; Krieg, Michael [Department of Molecular and Cellular Physiology, Stanford University, Stanford, United States]; Calixto, Andrea [Chile. Universidad Mayor. Centro de Genómica y Bioinformática]; Heiman, Maxwell G. [Estados Unidos. Boston Children’s Hospital]; Kuzmanov, Aleksandra [Estados Unidos. University of Wyoming]; Meli, Vijaykumar [Estados Unidos. University of California]; Chalfie, Martin [Estados Unidos. Columbia University]; Goodman, Miriam B. [Estados Unidos. Stanford University]; Shaham, Shai [Estados Unidos. The Rockefeller University. Laboratory of Developmental Genetics]; Frand, Alison [Estados Unidos. University of California]; Fay, David S. [Estados Unidos. University of Wyoming] (CIENCIAS, 2015)
      During development, biomechanical forces contour the body and provide shape to internal organs. Using genetic and molecular approaches in combination with a FRET-based tension sensor, we characterized a pulling force exerted ...


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