Listar Artículos WOS por autor "Hetz, Claudio"
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Correction: The necroptosis machinery mediates axonal degeneration in a model of Parkinson disease (vol 32, pg 274, 2019)
Oñate, Maritza [Ctr Integrat Biol, Fac Sci, Universidad Mayor, Chile]; Catenaccio, Alejandra [Ctr Integrat Biol, Fac Sci, Universidad Mayor, Chile]; Salvadores, Natalia [Ctr Integrat Biol, Fac Sci, Universidad Mayor, Chile]; Saquel, Cristian [Ctr Integrat Biol, Fac Sci, Universidad Mayor, Chile]; Martínez, Alexis; Moreno-González, Inés; Gamez, Nazaret; Soto, Paulina; Soto, Claudio; Hetz, Claudio; Court, Felipe A. [Ctr Integrat Biol, Fac Sci, Universidad Mayor, Chile] (Chile. Universidad Mayor, 2020-07)Correction to: Cell Death & Differentiation https://doi.org/10.1038/s41418-019-0408-4. Since online publication of this article, the authors noticed that reference details provided for references 65 and 66 were incorrect. ... -
DEF8 and Autophagy-Associated Genes are Altered in Mild Cognitive Impairment, Probable Alzheimer’s Disease Patients and a Transgenic Model of the Disease
Leyton, Esteban [Chile. Universidad Mayor. Centro de Biología Integrativa]; Matus, Diego [Chile. Universidad Mayor. Centro de Biología Integrativa]; Espinoza, Sandra [Chile. Universidad Mayor. Centro de Biología Integrativa]; Benítez, José Matías [Chile. Universidad Mayor. Centro de Biología Integrativa]; Cortés, Bastián [Chile. Universidad Mayor. Centro de Biología Integrativa]; Gómez, Wileidy [Chile. Universidad Mayor. Centro de Biología Integrativa]; Arévalo, Nohela B. [Chile. Universidad Mayor. Centro de Biología Integrativa]; Murgas, Paola [Chile. Universidad Mayor. Centro de Biología Integrativa]; Manque Ramírez, Patricio [Chile. Universidad Mayor. Centro de Genómica y Bioinformática]; Woehlbier, Ute [Chile. Universidad Mayor. Centro de Biología Integrativa]; Durán-Aniotz, Claudia; Hetz, Claudio; Behrens, María Isabel; San Martín, Carol D. [Chile. Universidad Mayor. Centro de Biología Integrativa]; Nassif, Melissa [Chile. Universidad Mayor. Centro de Biología Integrativa] (IOS Press, 2021-02-19)Background:Disturbances in the autophagy/endolysosomal systems are proposed as early signatures of Alzheimer’s disease (AD). However, few studies are available concerning autophagy gene expression in AD patients. Objective:To ... -
Endoplasmic reticulum stress leads to accumulation of wild-type SOD1 aggregates associated with sporadic amyotrophic lateral sclerosis
Woehlbier, Ute [Univ Mayor, Ctr Integrat Biol, Fac Sci, Santiago, Chile]; Medinas, Danilo B.; Rozas, Pablo; Martínez Traub, Francisca; Brown, Robert H.; Bosco, Daryl A.; Hetz, Claudio (NATL ACAD SCIENCES, 2018)Abnormal modifications to mutant superoxide dismutase 1 (SOD1) are linked to familial amyotrophic lateral sclerosis (fALS). Misfolding of wild-type SOD1 (SOD1(WT)) is also observed in postmortem tissue of a subset of ... -
ER Proteostasis Control of Neuronal Physiology and Synaptic Function
Martínez, Gabriela [Univ Mayor, Ctr Integrat Biol, Santiago, Chile]; Khatiwada, Sanjeev; Costa-Mattioli, Mauro; Hetz, Claudio (ELSEVIER SCIENCE LONDON, 2018)Neuronal proteostasis is maintained by the dynamic integration of different processes that regulate the synthesis, folding, quality control, and localization of proteins. The endoplasmic reticulum (ER) serves as a fundamental ... -
Unraveling the role of motoneuron autophagy in ALS
Nassif, Melissa [Univ Mayor, Fac Sci, CIB, Santiago, Chile]; Valenzuela, Vicente; Hetz, Claudio (TAYLOR & FRANCIS INC, 2018)In recent years, the role of autophagy in the pathogenesis of most neurodegenerative diseases has transitioned into a limbo of protective or detrimental effects. Genetic evidence indicates that mutations in autophagy-regulatory ...