Listar Artículos WOS por autor "Salech, Felipe"
Mostrando ítems 1-3 de 3
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Inverse Relationship Between Alzheimer's Disease and Cancer: How Immune Checkpoints Might Explain the Mechanisms Underlying Age-Related Diseases
SanMartin, Carol D. [Univ Mayor, Fac Ciencias, Ctr Integrat Biol, Santiago, Chile]; Rogers, Nicole K.; Romero, César; Ponce, Daniela P.; Salech, Felipe; López, Mercedes N.; Gleisner, Alejandra; Tempio, Fabian; Behrens, María I. (IOS PRESS, 2020)Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in the adult population. There is evidence of an inverse epidemiological relationship between AD and cancer, another prevalent age-related disease. ... -
Nicotinamide, a Poly [ADP-Ribose] Polymerase 1 (PARP-1) Inhibitor, as an Adjunctive Therapy for the Treatment of Alzheimer's Disease
Salech, Felipe; Ponce, Daniela P.; Paula-Lima, Andrea C.; SanMartin, Carol D. [Univ Mayor, Fac Ciencias, Ctr Integrat Biol, Chile]; Behrens, Maria I. (Frontiers Media S.A., 2020-08)Nicotinamide (vitamin B3) is a key component in the cellular production of Nicotinamide Adenine Dinucleotide (NAD) and has long been associated with neuronal development, survival and death. Numerous data suggest that ... -
Vitamin D Increases A beta 140 Plasma Levels and Protects Lymphocytes from Oxidative Death in Mild Cognitive Impairment Patients
SanMartin, Carol D. [Univ Mayor, Ctr Integrat Biol, Santiago, Chile]; Henríquez, Mauricio; Chacón, Carlos; Ponce, Daniela P.; Salech, Felipe; Rogers, Nicole K.; Behrens, María I. (BENTHAM SCIENCE PUBL LTD, 2018)Background: Mild cognitive impairment (MCI) has an increased rate of progression to dementia. Alterations of some metabolic factors, such as deficiency of vitamin D, are a risk factor for cognitive deterioration. Vitamin ...