Listar Artículos WOS por autor "Salvadores, Natalia [Centro de Biología Integrativa, Universidad Mayor, Chile]"
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Induction of IAPP amyloid deposition and associated diabetic abnormalities by a prion-like mechanism
Mukherjee A., Morales-Scheihing D., Moreno-Gonzalez I., Gonzalez C., Taylor-Presse K., Mendez N., Shahnawaz M., Gaber A.O., Sabek O.M., Fraga D.W., Soto C.; Salvadores, Natalia [Centro de Biología Integrativa, Universidad Mayor, Chile] (Rockefeller University Press, 2017)Although a large proportion of patients with type 2 diabetes (T2D) accumulate misfolded aggregates composed of the islet amyloid polypeptide (IAPP), its role in the disease is unknown. Here, we show that pancreatic IAPP ...