• Aberrant MUC1 accumulation in salivary glands of Sjogren's syndrome patients is reversed by TUDCA in vitro 

      Castro, Isabel; Albornoz, Nicolás; Aguilera, Sergio; Barrera, María-José; González, Sergio [Universidad Mayor, Chile]; Nuñez, Matilde; Carvajal, Patricia; Jara, Daniela; Lagos, Carolina; Molina, Claudio; Urzua, Ulises; Hermoso, Marcela A.; González, María-Julieta (Oxford University Press, 2020-04)
      Objectives. Xerostomia in SS patients has been associated with low quality and quantity of salivary mucins, which are fundamental for the hydration and protection of the oral mucosa. The aim of this study was to evaluate ...
    • Association of high 5-hydroxymethylcytosine levels with Ten Eleven Translocation 2 overexpression and inflammation in Sjogren's syndrome patients 

      González, Sergio [Univ Mayor, Fac Ciencias, Escuela Odontol, Santiago, Chile]; Lagos, Carolina; Caryajal, Patricia; Castro, Isabel; Jara, Daniela; Aguilera, Sergio; Barrera, María-José; Quest, Andrew F. G.; Bahamondes, Veronica; Molina, Claudio; Urzua, Ulises; Hermoso, Marcela A.; Leyton, Cecilia; González, María-Julieta (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2018)
      Here, we determined the 5-hydroxymethylcytosine (5hmC), 5-methylcytosine (5mC), Ten Eleven Translocation (TETs), and DNA methyltransferases (DNMTs) levels in epithelial and inflammatory cells of labial salivary glands (LSG) ...
    • Expression of JAK Proteins and Autophagy Markers in Sjogren's Syndrome Patients 

      González, Sergio [Univ Mayor, Fac Ciencias, Escuela Odontol, Santiago, Chile]; Barrera, María-José; Aguilera, Sergio; Castro, Isabel; Carvajal, Patricia; Molina, Claudio; Urzua, Ulises; González, María-Julieta (WILEY, 2018)
    • Impaired IRE1 alpha/XBP-1 pathway associated to DNA methylation might contribute to salivary gland dysfunction in Sjogren's syndrome patients 

      González, Sergio [Univ Mayor, Fac Ciencias, Escuela Odontol, Santiago, Chile]; Molina, Claudio [Univ Mayor, Fac Ciencias, Dept Patol Oral, Escuela Odontol, Santiago, Chile]; Sepúlveda, Denisse; Barrera, María-José; Castro, Isabel; Aguilera, Sergio; Carvajal, Patricia; Lagos, Carolina; Albornoz, Nicolás; Bahamondes, Verónica; Quest, Andrew F. G.; Urzua, Ulises; Leyton, Cecilia; Hermoso, Marcela A.; González, María-Julieta (OXFORD UNIV PRESS, 2018)
      Objectives. Labial salivary glands (LSGs) of SS patients show alterations related to endoplasmic reticulum stress. Glandular dysfunction could be partly the consequence of an altered inositol-requiring enzyme 1 alpha (IRE1 ...
    • The levels, subcellular distribution and posttranslational processing of salivary mucins are affected 

      González, Sergio [Univ Mayor, Santiago, Chile]; Castro, Isabel; Brockhausen, Inka; Aguilera, Sergio; Barrera, María-José; Urzua, Ulises; Leyton, Cecilia; Julieta González, María (CLINICAL & EXPER RHEUMATOLOGY, 2018)


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