• Genomic positional conservation identifies topological anchor point RNAs linked to developmental loci 

      Arias-Carrasco, Raúl [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Santiago, Chile]; Maracaja-Coutinho, Vinicius [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Santiago, Chile]; Amaral, Paulo P.; Leonardi, Tommaso; Han, Namshik; Vire, Emmanuelle; Gascoigne, Dennis K.; Buscher, Magdalena; Pandolfini, Luca; Zhang, Anda; Pluchino, Stefano; Nakaya, Helder, I; Hemberg, Martin; Shiekhattar, Ramin; Enright, Anton J.; Kouzarides, Tony (BMC, 2018)
      Background: The mammalian genome is transcribed into large numbers of long noncoding RNAs (lncRNAs), but the definition of functional lncRNA groups has proven difficult, partly due to their low sequence conservation and ...
    • Tracing the phylogenetic history of the Crl regulon through the Bacteria and Archaea genomes 

      Pérez-Rueda, E. [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Santiago, Chile]; Santos-Zavaleta, A.; Sánchez-Pérez, M.; Velazquez-Ramírez, D. A.; Collado-Vides, J. (BMC, 2019)
      Background: Crl, identified for curli production, is a small transcription factor that stimulates the association of the sigma(S) factor (RpoS) with the RNA polymerase core through direct and specific interactions, increasing ...
    • Transcriptional profiling of embryos lacking the lipoprotein receptor SR-B1 reveals a regulatory circuit governing a neurodevelopmental or metabolic decision during neural tube closure 

      Murgas, Leandro [Univ Mayor, Network Biol Lab, Ctr Genom & Bioinformat, Fac Sci, Santiago, Chile]; Contreras, Sebastián [Univ Mayor, Network Biol Lab, Ctr Genom & Bioinformat, Fac Sci, Santiago, Chile]; Martin, Alberto J. M. [Univ Mayor, Network Biol Lab, Ctr Genom & Bioinformat, Fac Sci, Santiago, Chile]; Santander, Nicolás; Lizama, Carlos; Molina, Paz; Quiroz, Alonso; Rivera, Katherine; Salas-Pérez, Francisca; Godoy, Alejandro; Rigotti, Attilio; Busso, Dolores (BMC, 2018)
      Background: The high-density lipoprotein receptor SR-B1 mediates cellular uptake of several lipid species, including cholesterol and vitamin E. During early mouse development, SR-B1 is located in the maternal-fetal interface, ...


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