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Bacterially produced metabolites protect C. elegans neurons from degeneration
(Public Library of Science, 2020-03)
Caenorhabditis elegans and its cognate bacterial diet comprise a reliable, widespread model to study diet and microbiota effects on host physiology. Nonetheless, how diet influences the rate at which neurons die remains ...
Cancer cells with defective oxidative phosphorylation require endoplasmic reticulum-to-mitochondria Ca2+ transfer for survival
(American Association for the Advancement of Science, 2020-07)
Spontaneous Ca2+ signaling from the InsP(3)R intracellular Ca2+ release channel to mitochondria is essential for optimal oxidative phosphorylation (OXPHOS) and ATP production. In cells with defective OXPHOS, reductive ...
Integrating conflict, lobbying, and compliance to predict the sustainability of natural resource use
(The Resilience Alliance, 2020-06)
Predictive models are sorely needed to guide the management of harvested natural resources worldwide, yet existing frameworks fail to integrate the dynamic and interacting governance processes driving unsustainable use. ...
Menopausia y factores de riesgo cardiovascular en mujeres chilenas
(Sociedad Medica de Santiago, 2020-02)
Background: Menopause exposes women to an increased cardiovascular risk. Aim: To determine the association between menopause and cardiovascular risk factors in Chilean adult women using data from the National Health Survey ...
Biomarkers Profile of People With Sarcopenia: A Cross-sectional Analysis From UK Biobank
(Elsevier Inc., 2020-12)
Objective: This study aimed to characterize the biomarker profile of sarcopenic vs nonsarcopenic men and women, using the current European Working Group on Sarcopenia in Older People (EWGSOP2) definition in the UK Biobank ...
Cancer cases and deaths attributable to lifestyle risk factors in Chile
(Univ Mayor, Ctr Invest Fisiol Ejercicio CIFE, Chile, 2020-07)
Background To identify modifiable risk factors that contribute to cancer holds important public health relevance for setting up prevention strategies. Therefore, the aim of this study was to estimate the proportion of ...
Biometric Analysis of Healthy Coronary Arteries in a Chilean Population: An Angiographic Study
(Universidad de la Frontera, 2020-12)
Thorough knowledge and understanding of coronary arteries and their anatomy is essential when performing cardiac surgery such as a coronary bypass. Coronary angiography is a minimally invasive method used to evaluate the ...
Association Between Walking Pace and Stroke Incidence Findings From the UK Biobank Prospective Cohort Study
(Lippincott Williams and Wilkins Ltd., 2020-05)
Background and Purpose- Stroke incidence in younger and middle-aged people is growing. Despite this, its associations in this subset of the stroke population are unknown, and prevention strategies are not tailored to meet ...
Deciphering the functional diversity of DNA-binding transcription factors in Bacteria and Archaea organisms
(Public Library of Science, 2020-08)
DNA-binding Transcription Factors (TFs) play a central role in regulation of gene expression in prokaryotic organisms, and similarities at the sequence level have been reported. These proteins are predicted with different ...
Connectivity of bacterial assemblages along the Loa River in the Atacama Desert, Chile
(PeerJ Inc., 2020-10)
The Loa River is the only perennial artery that crosses the Atacama Desert in northern Chile. It plays an important role in the ecological and economic development of the most water-stressed region, revealing the impact ...