Browsing Centro de Biología Integrativa (CBI) by Author "Farias, Paula; Cardenas, Cesar [Univ Mayor, Ctr Integrat Biol, Chile]"

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CD73 Ectonucleotidase Restrains CD8+T Cell Metabolic Fitness and Anti-tumoral Activity 1 of 1 CD73 Ectonucleotidase Restrains CD8+T Cell Metabolic Fitness and Anti-tumoral Activity

Briceño, Pedro; Rivas-Yañez, Elizabeth; Rosemblatt, Mariana V.; Parra-Tello, Brian; Vargas, Leonardo; Lladser, Alvaro; Salazar-Onfray, Flavio; Elorza, Alvaro A.; Rosemblatt, Mario; Bono, Maria Rosa; Sauma, Daniela; Farias, Paula; Cardenas, Cesar [Univ Mayor, Ctr Integrat Biol, Chile] (FRONTIERS MEDIA SA, 2021-02-18)

CD39 and CD73 are ectoenzymes that dephosphorylate ATP into its metabolites; ADP, AMP, and adenosine, and thus are considered instrumental in the development of immunosuppressive microenvironments. We have previously shown ...