Browsing Centro de Biología Integrativa (CBI) by Author "Labrador, L. [Univ Mayor, Ctr Genom & Bioinformat, Fac Sci]"

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Network approach identifies Pacer as an autophagy protein involved in ALS pathogenesis

Woehlbier, U. [Univ Mayor, Ctr Genom & Bioinformat, Fac Sci, Camino Piramide]; Manque, P. A.[Univ Mayor, Ctr Genom & Bioinformat, Fac Sci]; Hernández, M. F. [Univ Mayor, Ctr Genom & Bioinformat, Fac Sci, Camino Piramide]; Bergmann, C. A. [Univ Mayor, Ctr Genom & Bioinformat, Fac Sci, Camino Piramide]; Cortez, C. [Univ Mayor, Ctr Genom & Bioinformat, Fac Sci]; Cortés, B. I. [Univ Mayor, Ctr Genom & Bioinformat, Fac Sci]; Labrador, L. [Univ Mayor, Ctr Genom & Bioinformat, Fac Sci]; Arcos, J. [Univ Mayor, Ctr Genom & Bioinformat, Fac Sci]; Vicencio, E. [Univ Mayor, Ctr Genom & Bioinformat, Fac Sci]; Nassif, M. [Univ Mayor, Ctr Genom & Bioinformat, Fac Sci] (BMC, 2019)

BackgroundAmyotrophic lateral sclerosis (ALS) is a multifactorial fatal motoneuron disease without a cure. Ten percent of ALS cases can be pointed to a clear genetic cause, while the remaining 90% is classified as sporadic. ...