Browsing Centro de Biología Integrativa (CBI) by Author "Passos-Bueno, Maria Rita"

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Neural crest E-cadherin loss drives cleft lip/palate by epigenetic modulation via pro-inflammatory gene-environment interaction

Alvizi, Lucas; Nani, Diogo; Brito, Luciano Abreu; Kobayashi, Gerson Shigeru; Passos-Bueno, Maria Rita; Mayor, Roberto [Univ Mayor, Fac Sci, Ctr Integrat Biol, Chile] (Nature Publishing Group, 2023-05-24)

Gene-environment interactions are believed to play a role in multifactorial phenotypes, although poorly described mechanistically. Cleft lip/palate (CLP), the most common craniofacial malformation, has been associated with ...