• IRE1 alpha governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A 

      Vidal, Rene L. [Univ Mayor, Ctr Integrat Biol, Fac Sci, Santiago, Chile]; Rivera, Claudia A. [Univ Mayor, Ctr Integrat Biol, Fac Sci, Santiago, Chile]; Court, Felipe A. [Univ Mayor, Ctr Integrat Biol, Fac Sci, Santiago, Chile]; Urra, Hery; Henriquez, Daniel R.; Canovas, José; Villarroel-Campos, David; Carreras-Sureda, Amado; Pulgar, Eduardo; Molina, Emiliano; Hazari, Younis M.; Limia, Celia M.; Alvarez-Rojas, Sebastián; Figueroa, Ricardo; Rodríguez, Diego A.; Couve, Andrés; Qi, Ling; Chevet, Eric; Akai, Ryoko; Iwawaki, Takao; Concha, Miguel L.; Glavic, Alvaro; González-Billault, Christian; Hetz, Claudio (NATURE PUBLISHING GROUP, 2018)
      Maintenance of endoplasmic reticulum (ER) proteostasis is controlled by a signalling network known as the unfolded protein response (UPR). Here, we identified filamin A as a major binding partner of the ER stress transducer ...
    • Outside in: Unraveling the Role of Neuroinflammation in the Progression of Parkinson's Disease 

      Troncoso-Escudero, Paulina [Univ Mayor, Ctr Integrat Biol, Fac Sci, Santiago, Chile]; Parra, Alejandra [Univ Mayor, Ctr Integrat Biol, Fac Sci, Santiago, Chile]; Nassif, Melissa [Univ Mayor, Ctr Integrat Biol, Fac Sci, Santiago, Chile]; Vidal, Rene L. [Univ Mayor, Ctr Integrat Biol, Fac Sci, Santiago, Chile] (FRONTIERS MEDIA SA, 2018)
      Neuroinflammation is one of the most important processes involved in the pathogenesis of Parkinson's disease (PD). The current concept of neuroinflammation comprises an inflammation process, which occurs in the central ...


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